Systemic G-CSF attenuates cerebral inflammation and hypomyelination but does not reduce seizure burden in preterm sheep exposed to global hypoxia-ischemia

Experimental Neurology

Volumn 250, Issue , 2013, Pages 293-303

  Jellema, Reint K ^a,b   Lima Passos, Valéria ^a   Ophelders, Daan R M G ^a,b   Wolfs, Tim G A M ^a,b   Zwanenburg, Alex ^a,b   De Munter, Stephanie ^a,b   Nikiforou, Maria ^a,b   Collins, Jennifer J P ^a,b   Kuypers, Elke ^a,b   Bos, Gerard M J ^b   Steinbusch, Harry W ^a   Vanderlocht, Joris ^a,b   Andriessen, Peter ^c   Germeraad, Wilfred T V ^a,b   Kramer, Boris W ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c MÁXIMA MEDICAL CENTER   (Netherlands)

Author keywords

G CSF; Hypoxic ischemic encephalopathy; Neuroprotection; Preterm; Sheep model; Stem cells; White matter injury

Indexed keywords

CD34 ANTIGEN; MYELIN BASIC PROTEIN; MYELOPEROXIDASE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL OCCLUSION; BRAIN; BRAIN HYPOXIA; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN SLICE; CELL INVASION; CELL PROLIFERATION; DRUG MECHANISM; ELECTROENCEPHALOGRAM; ELECTROGRAPHY; FETUS; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HYPOXIC ISCHEMIC ENCEPHALOPATHY; INFLAMMATION; MICROGLIA; MYELINATION; NEUROPROTECTION; NEUTROPHIL; NONHUMAN; PREMATURITY; PRIORITY JOURNAL; SEIZURE; SHEEP; STEM CELL MOBILIZATION; UMBILICAL CORD; WHITE MATTER INJURY;

G-CSF; HYPOXIC-ISCHEMIC ENCEPHALOPATHY; NEUROPROTECTION; PRETERM; SHEEP MODEL; STEM CELLS; WHITE MATTER INJURY;

ANIMALS; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; ELECTROENCEPHALOGRAPHY; ENCEPHALITIS; FETAL HYPOXIA; FETUS; FLOW CYTOMETRY; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOHISTOCHEMISTRY; NERVE FIBERS, MYELINATED; NEUROPROTECTIVE AGENTS; SEIZURES; SHEEP;

EID: 84886391856     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.09.026     Document Type: Article

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