메뉴 건너뛰기




Volumn 52, Issue SUPPL1, 2013, Pages 139-147

Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: Risk and prognosis prediction

Author keywords

Case control; Genetic susceptibility; Molecular epidemiology; Single nucleotide polymorphism

Indexed keywords

PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3; PHOSPHOLIPASE; UNCLASSIFIED DRUG;

EID: 84886308722     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22057     Document Type: Article
Times cited : (63)

References (38)
  • 1
    • 63049133092 scopus 로고    scopus 로고
    • Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005
    • Altekruse SF, McGlynn KA, Reichman ME. Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005. J Clin Oncol 2009; 27:1485-1491.
    • (2009) J Clin Oncol , vol.27 , pp. 1485-1491
    • Altekruse, S.F.1    McGlynn, K.A.2    Reichman, M.E.3
  • 2
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
    • Browning JD, Szczepaniak LS, Dobbins R, et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity. Hepatology 2004; 40:1387-1395.
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 3
    • 0032146915 scopus 로고    scopus 로고
    • Host- and disease-specific factors affecting steatosis in chronic hepatitis C
    • Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Host- and disease-specific factors affecting steatosis in chronic hepatitis C. J Hepatol 1998; 29:198-206.
    • (1998) J Hepatol , vol.29 , pp. 198-206
    • Czaja, A.J.1    Carpenter, H.A.2    Santrach, P.J.3    Moore, S.B.4
  • 4
    • 11144307888 scopus 로고    scopus 로고
    • Narrative review: Hepatobiliary disease in type 2 diabetes mellitus
    • Tolman KG, Fonseca V, Tan MH, Dalpiaz A. Narrative review: Hepatobiliary disease in type 2 diabetes mellitus. Ann Intern Med 2004; 141:946-956.
    • (2004) Ann Intern Med , vol.141 , pp. 946-956
    • Tolman, K.G.1    Fonseca, V.2    Tan, M.H.3    Dalpiaz, A.4
  • 5
    • 6844258880 scopus 로고    scopus 로고
    • Drinking habits as cofactors of risk for alcohol induced liver damage. The Dionysos Study Group
    • Bellentani S, Saccoccio G, Costa G, et al. Drinking habits as cofactors of risk for alcohol induced liver damage. The Dionysos Study Group. Gut 1997; 41:845-850.
    • (1997) Gut , vol.41 , pp. 845-850
    • Bellentani, S.1    Saccoccio, G.2    Costa, G.3
  • 6
    • 79959517565 scopus 로고    scopus 로고
    • Human fatty liver disease: Old questions and new insights
    • Cohen JC, Horton JD, Hobbs HH. Human fatty liver disease: Old questions and new insights. Science 2011; 332:1519-1523.
    • (2011) Science , vol.332 , pp. 1519-1523
    • Cohen, J.C.1    Horton, J.D.2    Hobbs, H.H.3
  • 7
    • 70349770695 scopus 로고    scopus 로고
    • Epidemiology and natural history of non-alcoholic steatohepatitis
    • Argo CK, Caldwell SH. Epidemiology and natural history of non-alcoholic steatohepatitis. Clin Liver Dis 2009; 13:511-531.
    • (2009) Clin Liver Dis , vol.13 , pp. 511-531
    • Argo, C.K.1    Caldwell, S.H.2
  • 8
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection
    • Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection. Hepatology 2010; 51:1820-1832.
    • (2010) Hepatology , vol.51 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 9
    • 79953126783 scopus 로고    scopus 로고
    • Low concentrations of serum n-3 polyunsaturated fatty acids in non-alcoholic fatty liver disease patients with liver injury
    • Kishino T, Ohnishi H, Ohtsuka K, et al. Low concentrations of serum n-3 polyunsaturated fatty acids in non-alcoholic fatty liver disease patients with liver injury. Clin Chem Lab Med 2011; 49:159-162.
    • (2011) Clin Chem Lab Med , vol.49 , pp. 159-162
    • Kishino, T.1    Ohnishi, H.2    Ohtsuka, K.3
  • 10
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004; 114:147-152.
    • (2004) J Clin Invest , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 11
    • 56749096610 scopus 로고    scopus 로고
    • Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
    • Romeo S, Kozlitina J, Xing C, et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 2008; 40:1461-1465.
    • (2008) Nat Genet , vol.40 , pp. 1461-1465
    • Romeo, S.1    Kozlitina, J.2    Xing, C.3
  • 12
    • 53049090077 scopus 로고    scopus 로고
    • Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes
    • Yuan X, Waterworth D, Perry JR, et al. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet 2008; 83:520-528.
    • (2008) Am J Hum Genet , vol.83 , pp. 520-528
    • Yuan, X.1    Waterworth, D.2    Perry, J.R.3
  • 13
    • 77950607738 scopus 로고    scopus 로고
    • Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
    • Valenti L, Al-Serri A, Daly AK, et al. Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 2010; 51:1209-1217.
    • (2010) Hepatology , vol.51 , pp. 1209-1217
    • Valenti, L.1    Al-Serri, A.2    Daly, A.K.3
  • 14
    • 79952222716 scopus 로고    scopus 로고
    • Patatin-like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C
    • Valenti L, Rumi M, Galmozzi E, et al. Patatin-like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C. Hepatology 2011; 53:791-799.
    • (2011) Hepatology , vol.53 , pp. 791-799
    • Valenti, L.1    Rumi, M.2    Galmozzi, E.3
  • 15
    • 77956636268 scopus 로고    scopus 로고
    • The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
    • Rotman Y, Koh C, Zmuda JM, Kleiner DE, Liang TJ. The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology 2010; 52:894-903.
    • (2010) Hepatology , vol.52 , pp. 894-903
    • Rotman, Y.1    Koh, C.2    Zmuda, J.M.3    Kleiner, D.E.4    Liang, T.J.5
  • 16
    • 69249111667 scopus 로고    scopus 로고
    • A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity
    • Sookoian S, Castano GO, Burgueno AL, Gianotti TF, Rosselli MS, Pirola CJ. A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity. J Lipid Res 2009; 50:2111-2116.
    • (2009) J Lipid Res , vol.50 , pp. 2111-2116
    • Sookoian, S.1    Castano, G.O.2    Burgueno, A.L.3    Gianotti, T.F.4    Rosselli, M.S.5    Pirola, C.J.6
  • 17
    • 0036829556 scopus 로고    scopus 로고
    • Risk factors for hepatocellular carcinoma: Synergism of alcohol with viral hepatitis and diabetes mellitus
    • Hassan MM, Hwang LY, Hatten CJ, et al. Risk factors for hepatocellular carcinoma: Synergism of alcohol with viral hepatitis and diabetes mellitus. Hepatology 2002; 36:1206-1213.
    • (2002) Hepatology , vol.36 , pp. 1206-1213
    • Hassan, M.M.1    Hwang, L.Y.2    Hatten, C.J.3
  • 18
    • 51949118352 scopus 로고    scopus 로고
    • Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: Case-control study
    • Hassan MM, Spitz MR, Thomas MB, et al. Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: Case-control study. Int J Cancer 2008; 123:1883-1891.
    • (2008) Int J Cancer , vol.123 , pp. 1883-1891
    • Hassan, M.M.1    Spitz, M.R.2    Thomas, M.B.3
  • 19
    • 58149277470 scopus 로고    scopus 로고
    • The association of family history of liver cancer with hepatocellular carcinoma: A case-control study in the United States
    • Hassan MM, Spitz MR, Thomas MB, et al. The association of family history of liver cancer with hepatocellular carcinoma: A case-control study in the United States. J Hepatol 2009; 50:334-341.
    • (2009) J Hepatol , vol.50 , pp. 334-341
    • Hassan, M.M.1    Spitz, M.R.2    Thomas, M.B.3
  • 20
    • 66149088423 scopus 로고    scopus 로고
    • Association between hypothyroidism and hepatocellular carcinoma: A case-control study in the United States
    • Hassan MM, Kaseb A, Li D, et al. Association between hypothyroidism and hepatocellular carcinoma: A case-control study in the United States. Hepatology 2009; 49:1563-1570.
    • (2009) Hepatology , vol.49 , pp. 1563-1570
    • Hassan, M.M.1    Kaseb, A.2    Li, D.3
  • 21
    • 77951006620 scopus 로고    scopus 로고
    • Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma
    • Hassan MM, Curley SA, Li D, et al. Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma. Cancer 2010; 116:1938-1946.
    • (2010) Cancer , vol.116 , pp. 1938-1946
    • Hassan, M.M.1    Curley, S.A.2    Li, D.3
  • 22
    • 67349174005 scopus 로고    scopus 로고
    • A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans
    • Kotronen A, Johansson LE, Johansson LM, et al. A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans. Diabetologia 2009; 52:1056-1060.
    • (2009) Diabetologia , vol.52 , pp. 1056-1060
    • Kotronen, A.1    Johansson, L.E.2    Johansson, L.M.3
  • 23
    • 78650336759 scopus 로고    scopus 로고
    • Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease
    • Hotta K, Yoneda M, Hyogo H, et al. Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease. BMC Med Genet 2010; 11:172.
    • (2010) BMC Med Genet , vol.11 , pp. 172
    • Hotta, K.1    Yoneda, M.2    Hyogo, H.3
  • 24
    • 79961186012 scopus 로고    scopus 로고
    • PNPLA3 rs738409C/G polymorphism in cirrhosis: Relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence
    • Falleti E, Fabris C, Cmet S, et al. PNPLA3 rs738409C/G polymorphism in cirrhosis: Relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence. Liver Int 2011; 31:1137-1143.
    • (2011) Liver Int , vol.31 , pp. 1137-1143
    • Falleti, E.1    Fabris, C.2    Cmet, S.3
  • 25
    • 28844435344 scopus 로고    scopus 로고
    • Treatment and outcomes of treating of hepatocellular carcinoma among Medicare recipients in the United States: A population-based study
    • El-Serag HB, Siegel AB, Davila JA, et al. Treatment and outcomes of treating of hepatocellular carcinoma among Medicare recipients in the United States: A population-based study. J Hepatol 2006; 44:158-166.
    • (2006) J Hepatol , vol.44 , pp. 158-166
    • El-Serag, H.B.1    Siegel, A.B.2    Davila, J.A.3
  • 26
    • 0037315472 scopus 로고    scopus 로고
    • Phase II trial of systemic continuous fluorouracil and subcutaneous recombinant interferon Alfa-2b for treatment of hepatocellular carcinoma
    • Patt YZ, Hassan MM, Lozano RD, et al. Phase II trial of systemic continuous fluorouracil and subcutaneous recombinant interferon Alfa-2b for treatment of hepatocellular carcinoma. J Clin Oncol 2003; 21:421-427.
    • (2003) J Clin Oncol , vol.21 , pp. 421-427
    • Patt, Y.Z.1    Hassan, M.M.2    Lozano, R.D.3
  • 27
    • 13444303839 scopus 로고    scopus 로고
    • Thalidomide in the treatment of patients with hepatocellular carcinoma: A phase II trial
    • Patt YZ, Hassan MM, Lozano RD, et al. Thalidomide in the treatment of patients with hepatocellular carcinoma: A phase II trial. Cancer 2005; 103:749-755.
    • (2005) Cancer , vol.103 , pp. 749-755
    • Patt, Y.Z.1    Hassan, M.M.2    Lozano, R.D.3
  • 28
    • 3242785675 scopus 로고    scopus 로고
    • Oral capecitabine for the treatment of hepatocellular carcinoma, cholangiocarcinoma, and gallbladder carcinoma
    • Patt YZ, Hassan MM, Aguayo A, et al. Oral capecitabine for the treatment of hepatocellular carcinoma, cholangiocarcinoma, and gallbladder carcinoma. Cancer 2004; 101:578-586.
    • (2004) Cancer , vol.101 , pp. 578-586
    • Patt, Y.Z.1    Hassan, M.M.2    Aguayo, A.3
  • 29
    • 77952352488 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of fatty liver disease: Patatin-like phospholipase domain-containing 3 protein
    • Romeo S, Huang-Doran I, Baroni MG, Kotronen A. Unravelling the pathogenesis of fatty liver disease: Patatin-like phospholipase domain-containing 3 protein. Curr Opin Lipidol 2010; 21:247-252.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 247-252
    • Romeo, S.1    Huang-Doran, I.2    Baroni, M.G.3    Kotronen, A.4
  • 30
    • 27444433258 scopus 로고    scopus 로고
    • Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members
    • Lake AC, Sun Y, Li JL, et al. Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. J Lipid Res 2005; 46:2477-2487.
    • (2005) J Lipid Res , vol.46 , pp. 2477-2487
    • Lake, A.C.1    Sun, Y.2    Li, J.L.3
  • 31
    • 77949895032 scopus 로고    scopus 로고
    • A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis
    • He S, McPhaul C, Li JZ, et al. A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem 2010; 285:6706-6715.
    • (2010) J Biol Chem , vol.285 , pp. 6706-6715
    • He, S.1    McPhaul, C.2    Li, J.Z.3
  • 32
    • 33645828659 scopus 로고    scopus 로고
    • Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation
    • Reddy JK, Rao MS. Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation. Am J Physiol Gastrointest Liver Physiol 2006; 290:G852-G858.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Reddy, J.K.1    Rao, M.S.2
  • 33
    • 0029165057 scopus 로고
    • Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver
    • Teli MR, Day CP, Burt AD, Bennett MK, James OF. Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver. Lancet 1995; 346:987-990.
    • (1995) Lancet , vol.346 , pp. 987-990
    • Teli, M.R.1    Day, C.P.2    Burt, A.D.3    Bennett, M.K.4    James, O.F.5
  • 34
    • 33846221464 scopus 로고    scopus 로고
    • Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells
    • Xu L, Han C, Lim K, Wu T. Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells. Cancer Res 2006; 66:11859-11868.
    • (2006) Cancer Res , vol.66 , pp. 11859-11868
    • Xu, L.1    Han, C.2    Lim, K.3    Wu, T.4
  • 35
    • 30944455145 scopus 로고    scopus 로고
    • Insulin resistance: A metabolic pathway to chronic liver disease
    • Bugianesi E, McCullough AJ, Marchesini G. Insulin resistance: A metabolic pathway to chronic liver disease. Hepatology 2005; 42:987-1000.
    • (2005) Hepatology , vol.42 , pp. 987-1000
    • Bugianesi, E.1    McCullough, A.J.2    Marchesini, G.3
  • 36
    • 33750596002 scopus 로고    scopus 로고
    • Mechanisms of disease: Pathway-selective insulin resistance and microvascular complications of diabetes
    • Groop PH, Forsblom C, Thomas MC. Mechanisms of disease: Pathway-selective insulin resistance and microvascular complications of diabetes. Nat Clin Pract Endocrinol Metab 2005; 1:100-110.
    • (2005) Nat Clin Pract Endocrinol Metab , vol.1 , pp. 100-110
    • Groop, P.H.1    Forsblom, C.2    Thomas, M.C.3
  • 37
    • 78651328101 scopus 로고    scopus 로고
    • Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption
    • Davis JN, Le KA, Walker RW, et al. Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption. Am J Clin Nutr 2010; 92:1522-1527.
    • (2010) Am J Clin Nutr , vol.92 , pp. 1522-1527
    • Davis, J.N.1    Le, K.A.2    Walker, R.W.3
  • 38
    • 0021807618 scopus 로고
    • Confounding and misclassification
    • Greenland S, Robins JM. Confounding and misclassification. Am J Epidemiol 1985; 122:495-506.
    • (1985) Am J Epidemiol , vol.122 , pp. 495-506
    • Greenland, S.1    Robins, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.