Overcoming co-product inhibition in the nicotinamide independent asymmetric bioreduction of activated C=C-bonds using flavin-dependent ene-reductases

Biotechnology and Bioengineering

Volumn 110, Issue 12, 2013, Pages 3085-3092

  Winkler, Christoph K ^a   Clay, Dorina ^a   van Heerden, Esta ^b   Faber, Kurt ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF THE FREE STATE   (South Africa)

Author keywords

Disproportionation; Ene reductase; In situ co product removal; Old yellow enzyme

Indexed keywords

ASYMMETRIC BIOREDUCTION; CO-PRODUCTS; CONJUGATED ENONES; DISPROPORTIONATIONS; ENE-REDUCTASE; HYDROGEN TRANSFER; OLD YELLOW ENZYMES; POLYMERIC ADSORBENT;

AMIDES; PHENOLS;

ENZYME ACTIVITY;

12 OXOPHYTODIENOATE REDUCTASE 1 ISOENZYME; 12 OXOPHYTODIENOATE REDUCTASE 3 ISOENZYME; ALKENE; CRS ENZYME; CYCLOHEX 2 ENONE; ENE REDUCTASE; ENZYME; ESTROGEN BINDING PROTEIN; ESTROGEN BINDING PROTEIN 1; ISOENZYME; KLUYVEROMYCES LACTIS YELLOW ENZYME 1; LOT6P ENZYME; MORPHINONE REDUCTASE; N ETHYLMALEIMIDE REDUCTASE; NERA GLYCEROL TRINITRATE REDUCTASE; NICOTINAMIDE; NICOTINAMIDE DEPENDENT CYCLOHEXENONE REDUCTASE; NITROREDUCTASE; OXIDOREDUCTASE; PENTAERYTHRITYL TETRANITRATE REDUCTASE; PHENOL; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE 2; UNCLASSIFIED DRUG; XENA XENOBIOTIC REDUCTASE; XENB XENOBIOTIC REDUCTASE; YCND ENZYME; YHDA ENZYME; YQJM ENZYME;

ARTICLE; ASYMMETRIC CATALYSIS; BACILLUS SUBTILIS; CANDIDA ALBICANS; CONTROLLED STUDY; ENTEROBACTER CLOACAE; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; ENZYME SYNTHESIS; GEOBACILLUS; KLUYVEROMYCES LACTIS; NONHUMAN; PH; PSEUDOMONAS; PSEUDOMONAS PUTIDA; REACTION OPTIMIZATION; REACTION TIME; REDUCTION; RHIZOBIUM RADIOBACTER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES PASTORIANUS; SCAVENGING SYSTEM; STEREOCHEMISTRY; TEMPERATURE; THERMUS; TOMATO; YERSINIA; ZYMOMONAS MOBILIS;

DISPROPORTIONATION; ENE-REDUCTASE; IN SITU CO-PRODUCT REMOVAL; OLD YELLOW ENZYME;

ALKANES; COENZYMES; DINITROCRESOLS; ENZYME INHIBITORS; FLAVOPROTEINS; NIACINAMIDE; OXIDATION-REDUCTION; OXIDOREDUCTASES; PHENOL;

EID: 84886293347     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24981     Document Type: Article

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