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Volumn , Issue , 2012, Pages 23-41

How Relevant is Caenorhabditis elegans as a Model for the Analysis of Parasitic Nematode Biology?

Author keywords

Anthelmintic; Caenorhabditis elegans; Mode of action; Nematode; Parasitic; Target discovery

Indexed keywords


EID: 84886219602     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527652969.ch2     Document Type: Chapter
Times cited : (8)

References (104)
  • 1
    • 0031911065 scopus 로고    scopus 로고
    • Drug-resistant parasites of sheep: an emerging problem in the UK? Parasitol
    • Coles, G.C. (1998) Drug-resistant parasites of sheep: an emerging problem in the UK? Parasitol. Today, 14, 86-88.
    • (1998) Today , vol.14 , pp. 86-88
    • Coles, G.C.1
  • 2
    • 79953066184 scopus 로고    scopus 로고
    • Anthelmintic resistance in nematode parasites of cattle: a global issue?
    • Sutherland, I.A. and Leathwick, D.M. (2011) Anthelmintic resistance in nematode parasites of cattle: a global issue? Trends Parasitol., 27, 176-181.
    • (2011) Trends Parasitol , vol.27 , pp. 176-181
    • Sutherland, I.A.1    Leathwick, D.M.2
  • 3
    • 85035400913 scopus 로고    scopus 로고
    • Epidemiology and control of human gastrointestinal parasites in children
    • Harhay, M.O., Horton, J., and Olliaro, P.L. (2010) Epidemiology and control of human gastrointestinal parasites in children. Expert Rev. Anti Infect. Ther., 8, 219-234.
    • (2010) Expert Rev. Anti Infect. Ther. , vol.8 , pp. 219-234
    • Harhay, M.O.1    Horton, J.2    Olliaro, P.L.3
  • 5
    • 0002773573 scopus 로고
    • The use of Caenorhabditis elegans for anthelmintic screening
    • Simpkins, K.G. and Coles, G.C. (1981) The use of Caenorhabditis elegans for anthelmintic screening. J. Chem. Technol. Biotechnol., 31, 66-69.
    • (1981) J. Chem. Technol. Biotechnol. , vol.31 , pp. 66-69
    • Simpkins, K.G.1    Coles, G.C.2
  • 6
    • 0019253922 scopus 로고
    • The genetics of levamisole resistance in the nematode Caenorhabditis elegans
    • Lewis, J.A., Wu, C.-H., Berg, H., and Levine, J.H. (1980) The genetics of levamisole resistance in the nematode Caenorhabditis elegans. Genetics, 95, 905-928.
    • (1980) Genetics , vol.95 , pp. 905-928
    • Lewis, J.A.1    Wu, C.-H.2    Berg, H.3    Levine, J.H.4
  • 7
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner, S. (1974) The genetics of Caenorhabditis elegans. Genetics, 77, 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 8
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. elegans: a platform for investigating biology
    • C. elegans Sequencing Consortium
    • C. elegans Sequencing Consortium (1998) Genome sequence of the nematode, C. elegans: a platform for investigating biology. Science, 282, 2012-2018.
    • (1998) Science , vol.282 , pp. 2012-2018
  • 9
    • 0032509180 scopus 로고    scopus 로고
    • Caenorhabditis elegans is a nematode
    • Blaxter, M. (1998) Caenorhabditis elegans is a nematode. Science, 282, 2041-2046.
    • (1998) Science , vol.282 , pp. 2041-2046
    • Blaxter, M.1
  • 11
    • 0025942107 scopus 로고
    • Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences
    • Mello, C.C., Kramer, J.M., Stinchcomb, D., and Ambros, V. (1991) Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J., 10, 3959-3970.
    • (1991) EMBO J , vol.10 , pp. 3959-3970
    • Mello, C.C.1    Kramer, J.M.2    Stinchcomb, D.3    Ambros, V.4
  • 12
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., Xu, S., Montgomery, M.K., Kostas, S.A., Driver, S.E., and Mello, C.C. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 13
    • 0027328348 scopus 로고
    • Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank
    • Zwaal, R.R., Broeks, A., van Meurs, J., Groenen, J.T., and Plasterk, R.H. (1993) Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank. Proc. Natl. Acad. Sci. USA, 90, 7431-7435.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7431-7435
    • Zwaal, R.R.1    Broeks, A.2    van Meurs, J.3    Groenen, J.T.4    Plasterk, R.H.5
  • 14
    • 0032033513 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model for parasitic nematodes
    • Bürglin, T.R., Lobos, E., and Blaxter, M.L. (1998) Caenorhabditis elegans as a model for parasitic nematodes. Int. J. Parasitol., 28, 395-411.
    • (1998) Int. J. Parasitol. , vol.28 , pp. 395-411
    • Bürglin, T.R.1    Lobos, E.2    Blaxter, M.L.3
  • 15
    • 0035935627 scopus 로고    scopus 로고
    • Caenorhabditis elegans: how good a model for veterinary parasites? Vet
    • Geary, T.G. and Thompson, D.P. (2001) Caenorhabditis elegans: how good a model for veterinary parasites? Vet. Parasitol., 101, 371-386.
    • (2001) Parasitol , vol.101 , pp. 371-386
    • Geary, T.G.1    Thompson, D.P.2
  • 16
    • 20444505132 scopus 로고    scopus 로고
    • The use of Caenorhabditis elegans in parasitic nematode research
    • Gilleard, J.S. (2004) The use of Caenorhabditis elegans in parasitic nematode research. Parasitology, 128, S49-S70.
    • (2004) Parasitology , vol.128
    • Gilleard, J.S.1
  • 17
    • 38449113796 scopus 로고    scopus 로고
    • Anthelmintic drugs
    • (ed. The C. elegans Research Community), doi:10.1895/wormbook.1.143.1
    • Holden-Dye, L. and Walker, R. (2007) Anthelmintic drugs, in WormBook (ed. The C. elegans Research Community), doi: 10.1895/wormbook.1.143.1.
    • (2007) WormBook
    • Holden-Dye, L.1    Walker, R.2
  • 21
    • 34249813137 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature. Invert
    • Jones, A., Davis, P., Hodgkin, J., and Sattelle, D. (2007) The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature. Invert. Neurosci., 7, 129-131.
    • (2007) Neurosci , vol.7 , pp. 129-131
    • Jones, A.1    Davis, P.2    Hodgkin, J.3    Sattelle, D.4
  • 22
  • 25
    • 56149121546 scopus 로고    scopus 로고
    • Intestinal transcriptomes of nematodes:comparison of the parasites Ascaris suum and Haemonchus contortus with the freeliving Caenorhabditis elegans
    • Yin, Y., Martin, J., Abubucker, S., Scott, A.L., McCarter, J.P., Wilson, R.K., Jasmer, D.P., and Mitreva, M. (2008) Intestinal transcriptomes of nematodes:comparison of the parasites Ascaris suum and Haemonchus contortus with the freeliving Caenorhabditis elegans. PLoS Negl. Trop. Dis., 2, e269.
    • (2008) PLoS Negl. Trop. Dis. , vol.2
    • Yin, Y.1    Martin, J.2    Abubucker, S.3    Scott, A.L.4    McCarter, J.P.5    Wilson, R.K.6    Jasmer, D.P.7    Mitreva, M.8
  • 26
    • 59249105525 scopus 로고    scopus 로고
    • The genome of Brugia malayi - all worms are not created equal
    • Scott, A.L. and Ghedin, E. (2009) The genome of Brugia malayi - all worms are not created equal. Parasitol. Int., 58, 6-11.
    • (2009) Parasitol. Int. , vol.58 , pp. 6-11
    • Scott, A.L.1    Ghedin, E.2
  • 27
    • 52949136971 scopus 로고    scopus 로고
    • The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism
    • Dieterich, C., Clifton, S., Schuster, L., Chinwalla, A., Delehaunty, K., Dinkelacker, I., Fulton, L. et al. (2008) The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism. Nat. Genet., 40, 1193-1198.
    • (2008) Nat. Genet. , vol.40 , pp. 1193-1198
    • Dieterich, C.1    Clifton, S.2    Schuster, L.3    Chinwalla, A.4    Delehaunty, K.5    Dinkelacker, I.6    Fulton, L.7
  • 28
    • 66149137646 scopus 로고    scopus 로고
    • Molecular cloning of a dominant roller mutant and establishment of DNA-mediated transformation in the nematode Pristionchus pacificus
    • Schlager, B., Wang, X., Braach, G., and Sommer, R.J. (2009) Molecular cloning of a dominant roller mutant and establishment of DNA-mediated transformation in the nematode Pristionchus pacificus. Genetics, 47, 300-304.
    • (2009) Genetics , vol.47 , pp. 300-304
    • Schlager, B.1    Wang, X.2    Braach, G.3    Sommer, R.J.4
  • 29
    • 67949094440 scopus 로고    scopus 로고
    • Transgenesis in parasitic nematodes: building a better array
    • Lok, J.B. (2009) Transgenesis in parasitic nematodes: building a better array. Trends Parasitol., 25, 345-347.
    • (2009) Trends Parasitol , vol.25 , pp. 345-347
    • Lok, J.B.1
  • 30
    • 38549117942 scopus 로고    scopus 로고
    • The phylogenetic relationships of Caenorhabditis and other rhabditids
    • (ed. The C. elegans Research Community), doi: 10.1895/wormbook.1.11.1
    • Kiontke, K. and Fitch, D. (2005) The phylogenetic relationships of Caenorhabditis and other rhabditids, in WormBook (ed. The C. elegans Research Community), doi: 10.1895/ wormbook.1.11.1.
    • (2005) WormBook
    • Kiontke, K.1    Fitch, D.2
  • 33
    • 33646816759 scopus 로고    scopus 로고
    • Using Caenorhabditis elegans for functional analysis of genes of parasitic nematodes
    • Britton, C. and Murray, L. (2006) Using Caenorhabditis elegans for functional analysis of genes of parasitic nematodes. Int. J. Parasitol., 36, 651-659.
    • (2006) Int. J. Parasitol. , vol.36 , pp. 651-659
    • Britton, C.1    Murray, L.2
  • 34
    • 0032886218 scopus 로고    scopus 로고
    • Identification of promoter elements of parasite nematode genes in transgenic Caenorhabditis elegans
    • Britton, C., Redmond, D.L., Knox, D.P., McKerrow, J.H., and Barry, J.D. (1999) Identification of promoter elements of parasite nematode genes in transgenic Caenorhabditis elegans. Mol. Biochem. Parasitol., 103, 171-181.
    • (1999) Mol. Biochem. Parasitol. , vol.103 , pp. 171-181
    • Britton, C.1    Redmond, D.L.2    Knox, D.P.3    McKerrow, J.H.4    Barry, J.D.5
  • 35
    • 0028987527 scopus 로고
    • b-Tubulin genes from the parasitic nematodeHaemonchus contortus modulate drug resistance in Caenorhabditis elegans
    • Kwa, M.S.G.,Veenstra, J.G.,Van Dijk, M., and Roos, M.H. (1995) b-Tubulin genes from the parasitic nematodeHaemonchus contortus modulate drug resistance in Caenorhabditis elegans. J. Mol. Biol., 246, 500-510.
    • (1995) J. Mol. Biol. , vol.246 , pp. 500-510
    • Kwa, M.S.G.1    Veenstra, J.G.2    Van Dijk, M.3    Roos, M.H.4
  • 36
    • 0024792625 scopus 로고
    • Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity
    • Driscoll, M., Dean, E., Reilly, E., Bergholz, E., and Chalfie, M. (1989) Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity. J. Cell Biol., 109, 2993-3003.
    • (1989) J. Cell Biol. , vol.109 , pp. 2993-3003
    • Driscoll, M.1    Dean, E.2    Reilly, E.3    Bergholz, E.4    Chalfie, M.5
  • 37
    • 0346787809 scopus 로고    scopus 로고
    • Ectopic expression of a Haemonchus contortus GATA transcription factor in Caenorhabditis elegans reveals conserved function in spite of extensive sequence divergence
    • Couthier, A., Smith, J., McGarr, P., Craig, B., andGilleard, J.S. (2004) Ectopic expression of a Haemonchus contortus GATA transcription factor in Caenorhabditis elegans reveals conserved function in spite of extensive sequence divergence. Mol. Biochem. Parasitol., 133, 241-253.
    • (2004) Mol. Biochem. Parasitol. , vol.133 , pp. 241-253
    • Couthier, A.1    Smith, J.2    McGarr, P.3    Craig, B.4    Gilleard, J.S.5
  • 38
    • 0032582727 scopus 로고    scopus 로고
    • Cloning of a trans-spliced glyceraldehyde-3-phosphatedehydrogenase gene from the potato cyst nematode Globodera rostochiensis and expression of its putative promoter region in Caenorhabditis elegans
    • Qin, L., Smant, G., Stokkermans, J., Bakker, J., Schots, A., and Helder, J. (1998) Cloning of a trans-spliced glyceraldehyde-3-phosphatedehydrogenase gene from the potato cyst nematode Globodera rostochiensis and expression of its putative promoter region in Caenorhabditis elegans. Mol. Biochem. Parasitol., 96, 59-67.
    • (1998) Mol. Biochem. Parasitol. , vol.96 , pp. 59-67
    • Qin, L.1    Smant, G.2    Stokkermans, J.3    Bakker, J.4    Schots, A.5    Helder, J.6
  • 39
    • 0021688468 scopus 로고
    • Two isoenzymes of glyceraldehyde-3-phosphate dehydrogenase in Caenorhabditis elegans. Isolation, properties, and immunochemical characterization
    • Yarbrough, P.O. and Hecht, R.M. (1984) Two isoenzymes of glyceraldehyde-3-phosphate dehydrogenase in Caenorhabditis elegans. Isolation, properties, and immunochemical characterization. J. Biol. Chem., 259, 14711-14720.
    • (1984) J. Biol. Chem. , vol.259 , pp. 14711-14720
    • Yarbrough, P.O.1    Hecht, R.M.2
  • 40
    • 0037258067 scopus 로고    scopus 로고
    • Functional analysis of the glutathione S-transferase 3 from Onchocerca volvulus (Ov-GST-3): a parasiteGSTconfers increased resistance to oxidative stress in Caenorhabditis elegans
    • Kampkötter, A., Volkmann, T.E., de Castro, S.H., Leiers, B., Klotz, L.-O., Johnson, T.E., Link, C.D., and Henkle-Dührsen, K. (2003) Functional analysis of the glutathione S-transferase 3 from Onchocerca volvulus (Ov-GST-3): a parasiteGSTconfers increased resistance to oxidative stress in Caenorhabditis elegans. J. Mol. Biol., 325, 25-37.
    • (2003) J. Mol. Biol. , vol.325 , pp. 25-37
    • Kampkötter, A.1    Volkmann, T.E.2    de Castro, S.H.3    Leiers, B.4    Klotz, L.-O.5    Johnson, T.E.6    Link, C.D.7    Henkle-Dührsen, K.8
  • 41
    • 0030659557 scopus 로고    scopus 로고
    • The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • Ogg, S., Paradis, S., Gottlieb, S., Patterson, G.I., Lee, L., Tissenbaum, H.A., and Ruvkun, G. (1997) The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature, 389, 994-999.
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5    Tissenbaum, H.A.6    Ruvkun, G.7
  • 42
    • 33644872044 scopus 로고    scopus 로고
    • The fork head transcription factor FKTF-1b from Strongyloides stercoralis restores DAF-16 developmental function to mutant Caenorhabditis elegans
    • Massey Jr, H.C., Bhopale, M.K., Li, X., Castelletto, M., and Lok, J.B. (2006) The fork head transcription factor FKTF-1b from Strongyloides stercoralis restores DAF-16 developmental function to mutant Caenorhabditis elegans. Int. J. Parasitol., 36, 347-352.
    • (2006) Int. J. Parasitol. , vol.36 , pp. 347-352
    • Massey Jr., H.C.1    Bhopale, M.K.2    Li, X.3    Castelletto, M.4    Lok, J.B.5
  • 43
    • 67650395589 scopus 로고    scopus 로고
    • Analysis of the translationally controlled tumour protein in the nematodes Ostertagia ostertagi and Caenorhabditis elegans suggests a pivotal role in egg production
    • Meyvis, Y., Houthoofd, W., Visser, A., Borgonie, G., Gevaert, K., Vercruysse, J., Claerebout, E., and Geldhof, P. (2009) Analysis of the translationally controlled tumour protein in the nematodes Ostertagia ostertagi and Caenorhabditis elegans suggests a pivotal role in egg production. Int. J. Parasitol., 39, 1205-1213.
    • (2009) Int. J. Parasitol. , vol.39 , pp. 1205-1213
    • Meyvis, Y.1    Houthoofd, W.2    Visser, A.3    Borgonie, G.4    Gevaert, K.5    Vercruysse, J.6    Claerebout, E.7    Geldhof, P.8
  • 44
    • 0035889640 scopus 로고    scopus 로고
    • Regulation of the pharynx ofCaenorhabditis elegans by 5-HT, octopamine, and FMRFamide-like neuropeptides
    • Rogers, C.M., Walker, R.J., Burke, J.F., and Holden-Dye, L. (2001) Regulation of the pharynx ofCaenorhabditis elegans by 5-HT, octopamine, and FMRFamide-like neuropeptides. J. Neurobiol., 49, 235-244.
    • (2001) J. Neurobiol. , vol.49 , pp. 235-244
    • Rogers, C.M.1    Walker, R.J.2    Burke, J.F.3    Holden-Dye, L.4
  • 45
    • 27744446005 scopus 로고    scopus 로고
    • Role of a FMRFamide-like family of neuropeptides in the pharyngeal nervous system of Caenorhabditis elegans
    • Papaioannou, S., Marsden, D., Franks, C.J., Walker, R.J., and Holden-Dye, L. (2005) Role of a FMRFamide-like family of neuropeptides in the pharyngeal nervous system of Caenorhabditis elegans. J. Neurobiol., 65, 304-319.
    • (2005) J. Neurobiol. , vol.65 , pp. 304-319
    • Papaioannou, S.1    Marsden, D.2    Franks, C.J.3    Walker, R.J.4    Holden-Dye, L.5
  • 46
    • 0141503432 scopus 로고    scopus 로고
    • Whole-genome analysis of 60 G proteincoupled receptors in Caenorhabditis elegans by gene knockout with RNAi
    • Keating, C., Kriek, N., Daniels, M., Ashcroft, N., Hopper, N., Siney, E., Holden-Dye, L., and Burke, J. (2003) Whole-genome analysis of 60 G proteincoupled receptors in Caenorhabditis elegans by gene knockout with RNAi. Curr. Biol., 13, 1715-1720.
    • (2003) Curr. Biol. , vol.13 , pp. 1715-1720
    • Keating, C.1    Kriek, N.2    Daniels, M.3    Ashcroft, N.4    Hopper, N.5    Siney, E.6    Holden-Dye, L.7    Burke, J.8
  • 48
    • 77951937499 scopus 로고    scopus 로고
    • A review of FMRFamide- and RFamide-like peptides in metazoa
    • Walker, R., Papaioannou, S., and Holden-Dye, L. (2009) A review of FMRFamide- and RFamide-like peptides in metazoa. Invert. Neurosci., 9, 111-153.
    • (2009) Invert. Neurosci. , vol.9 , pp. 111-153
    • Walker, R.1    Papaioannou, S.2    Holden-Dye, L.3
  • 52
    • 3342976389 scopus 로고    scopus 로고
    • Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans?
    • Komuniecki, R.W., Hobson, R.J., Rex, E.B., Hapiak, V.M., and Komuniecki, P.R. (2004) Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans? Mol. Biochem. Parasitol., 137, 1-11.
    • (2004) Mol Biochem. Parasitol. , vol.137 , pp. 1-11
    • Komuniecki, R.W.1    Hobson, R.J.2    Rex, E.B.3    Hapiak, V.M.4    Komuniecki, P.R.5
  • 53
    • 0038647394 scopus 로고    scopus 로고
    • Characterization of a novel G-protein coupled receptor from the parasitic nematode H. contortus with high affinity for serotonin
    • Smith, M.W., Borts, T.L., Emkey, R., Cook, C.A., Wiggins, C.J., and Gutierrez, J.A. (2003) Characterization of a novel G-protein coupled receptor from the parasitic nematode H. contortus with high affinity for serotonin. J. Neurochem., 86, 255-266.
    • (2003) J. Neurochem. , vol.86 , pp. 255-266
    • Smith, M.W.1    Borts, T.L.2    Emkey, R.3    Cook, C.A.4    Wiggins, C.J.5    Gutierrez, J.A.6
  • 55
    • 65649094244 scopus 로고    scopus 로고
    • A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response
    • Pirri, J.K., McPherson, A.D., Donnelly, J.L., Francis, M.M., and Alkema, M.J. (2009) A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response. Neuron, 62, 526-538.
    • (2009) Neuron , vol.62 , pp. 526-538
    • Pirri, J.K.1    McPherson, A.D.2    Donnelly, J.L.3    Francis, M.M.4    Alkema, M.J.5
  • 56
    • 67650076325 scopus 로고    scopus 로고
    • Ligand-gated chloride channels are receptors for biogenic amines in C. elegans
    • Ringstad, N., Abe, N., and Horvitz, H.R. (2009) Ligand-gated chloride channels are receptors for biogenic amines in C. elegans. Science, 325, 96-100.
    • (2009) Science , vol.325 , pp. 96-100
    • Ringstad, N.1    Abe, N.2    Horvitz, H.R.3
  • 57
    • 77449112275 scopus 로고    scopus 로고
    • Nematicidal activity of two monoterpenoids and SER-2 tyramine receptor of Caenorhabditis elegans
    • Lei, J., Leser, M., and Enan, E. (2010) Nematicidal activity of two monoterpenoids and SER-2 tyramine receptor of Caenorhabditis elegans. Biochem. Pharmacol., 79, 1062-1071.
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 1062-1071
    • Lei, J.1    Leser, M.2    Enan, E.3
  • 58
    • 17444443158 scopus 로고    scopus 로고
    • Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits
    • Fleming, J., Squire, M., Barnes, T., Tornoe, C., Matsuda, K., Ahnn, J., Fire, A., Sulston, J. et al. (1997) Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits. J. Neurosci., 17, 5843-5857.
    • (1997) J. Neurosci. , vol.17 , pp. 5843-5857
    • Fleming, J.1    Squire, M.2    Barnes, T.3    Tornoe, C.4    Matsuda, K.5    Ahnn, J.6    Fire, A.7    Sulston, J.8
  • 59
    • 35148867124 scopus 로고    scopus 로고
    • The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans
    • Guest, M., Bull, K., Walker, R.J., Amliwala, K., O'Connor, V., Harder, A., Holden-Dye, L., and Hopper, N.A. (2007) The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans. Int. J. Parasitol., 37, 1577-1588.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 1577-1588
    • Guest, M.1    Bull, K.2    Walker, R.J.3    Amliwala, K.4    O'Connor, V.5    Harder, A.6    Holden-Dye, L.7    Hopper, N.A.8
  • 60
    • 33646799113 scopus 로고    scopus 로고
    • Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study
    • Brown, L.A., Jones, A.K., Buckingham, S.D., Mee, C.J., and Sattelle, D.B. (2006) Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study. Int. J. Parasitol., 36, 617-624.
    • (2006) Int. J. Parasitol. , vol.36 , pp. 617-624
    • Brown, L.A.1    Jones, A.K.2    Buckingham, S.D.3    Mee, C.J.4    Sattelle, D.B.5
  • 61
    • 84987034433 scopus 로고
    • Mode of action of the anthelmintics morantel, pyrantel and levamisole on the muscle cell membrane of the nematode Ascaris suum
    • Harrow, I.D. and Gration, K.A.F. (1985) Mode of action of the anthelmintics morantel, pyrantel and levamisole on the muscle cell membrane of the nematode Ascaris suum. Pesticide Sci., 16, 662-672.
    • (1985) Pesticide Sci , vol.16 , pp. 662-672
    • Harrow, I.D.1    Gration, K.A.F.2
  • 62
    • 34347394336 scopus 로고    scopus 로고
    • Mode of action of levamisole and pyrantel, anthelmintic resistance E153 and Q57
    • Martin, R.J. and Robertson, A.P. (2007) Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57. Parasitology, 134, 1093-1104.
    • (2007) Parasitology , vol.134 , pp. 1093-1104
    • Martin, R.J.1    Robertson, A.P.2
  • 63
    • 57449098443 scopus 로고    scopus 로고
    • Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisolesensitive acetylcholine receptor
    • Boulin, T., Gielen, M., Richmond, J.E., Williams, D.C., Paoletti, P., and Bessereau, J.-L. (2008) Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisolesensitive acetylcholine receptor. Proc. Natl. Acad. Sci. USA, 105, 18590-18595.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 18590-18595
    • Boulin, T.1    Gielen, M.2    Richmond, J.E.3    Williams, D.C.4    Paoletti, P.5    Bessereau, J.-L.6
  • 65
    • 11144349105 scopus 로고    scopus 로고
    • Brief application of AF2 produces long lasting potentiation of nAChR responses in Ascaris suum
    • Trailovic, S.M., Clark, C.L., Robertson, A.P., and Martin, R.J. (2005) Brief application of AF2 produces long lasting potentiation of nAChR responses in Ascaris suum. Mol. Biochem. Parasitol., 139, 51-64.
    • (2005) Mol. Biochem. Parasitol. , vol.139 , pp. 51-64
    • Trailovic, S.M.1    Clark, C.L.2    Robertson, A.P.3    Martin, R.J.4
  • 66
    • 0345257312 scopus 로고    scopus 로고
    • Methyridine (2-[2-methoxyethyl]-pyridine]) and levamisole activate different ACh receptor subtypes in nematode parasites: a new lead for levamisole-resistance
    • Martin, R.J., Bai, G., Clark, C.L., and Robertson, A.P. (2003)Methyridine (2-[2-methoxyethyl]-pyridine]) and levamisole activate different ACh receptor subtypes in nematode parasites: a new lead for levamisole-resistance. Br. J. Pharmacol., 140, 1068-1076.
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 1068-1076
    • Martin, R.J.1    Bai, G.2    Clark, C.L.3    Robertson, A.P.4
  • 67
    • 51349087230 scopus 로고    scopus 로고
    • Levamisole resistance resolved at the single-channel level in Caenorhabditis elegans
    • Qian, H., Robertson, A.P., Powell-Coffman, J.A., and Martin, R.J. (2008) Levamisole resistance resolved at the single-channel level in Caenorhabditis elegans. FASEB J., 22, 3247-3254.
    • (2008) FASEB J , vol.22 , pp. 3247-3254
    • Qian, H.1    Robertson, A.P.2    Powell-Coffman, J.A.3    Martin, R.J.4
  • 68
    • 48349144172 scopus 로고    scopus 로고
    • Identification of the amino-acetonitrile derivative monepantel (AAD 1566) as a new anthelmintic drug development candidate
    • Kaminsky, R., Gauvry, N., Schorderet Weber, S., Skripsky, T., Bouvier, J., Wenger, A., Schroeder, F. et al. (2008) Identification of the amino-acetonitrile derivative monepantel (AAD 1566) as a new anthelmintic drug development candidate. Parasitol. Res., 103, 931-939.
    • (2008) Parasitol. Res. , vol.103 , pp. 931-939
    • Kaminsky, R.1    Gauvry, N.2    Schorderet Weber, S.3    Skripsky, T.4    Bouvier, J.5    Wenger, A.6    Schroeder, F.7
  • 69
    • 66349115612 scopus 로고    scopus 로고
    • Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel
    • Rufener, L., Mäser, P., Roditi, I., and Kaminsky, R. (2009) Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel. PLoS Pathog., 5, e1000380.
    • (2009) PLoS Pathog , vol.5
    • Rufener, L.1    Mäser, P.2    Roditi, I.3    Kaminsky, R.4
  • 70
    • 77958126455 scopus 로고    scopus 로고
    • Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus
    • Rufener, L., Baur, R., Kaminsky, R., Mäser, P., and Sigel, E. (2010) Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus. Mol. Pharmacol., 78, 895-902.
    • (2010) Mol. Pharmacol. , vol.78 , pp. 895-902
    • Rufener, L.1    Baur, R.2    Kaminsky, R.3    Mäser, P.4    Sigel, E.5
  • 71
    • 78149325386 scopus 로고    scopus 로고
    • Phylogenomics of ligand-gated ion channels predicts monepantel effect
    • Rufener, L., Keiser, J., Kaminsky, R., Mäser, P., and Nilsson, D. (2010) Phylogenomics of ligand-gated ion channels predicts monepantel effect. PLoS Pathog., 6, e1001091.
    • (2010) PLoS Pathog , vol.6
    • Rufener, L.1    Keiser, J.2    Kaminsky, R.3    Mäser, P.4    Nilsson, D.5
  • 72
    • 0024325529 scopus 로고
    • Avermectin binding in Caenorhabditis elegans A two-state model for the avermectin binding site
    • Schaeffer, J.M. and Haines, H.W. (1989) Avermectin binding in Caenorhabditis elegans. A two-state model for the avermectin binding site. Biochem. Pharmacol., 38, 2329-2338.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 2329-2338
    • Schaeffer, J.M.1    Haines, H.W.2
  • 73
    • 0026015047 scopus 로고
    • Avermectin-sensitive chloride currents induced by Caenorhabditis elegans RNA in Xenopus oocytes
    • Arena, J.P., Liu, K.K., Paress, P.S., and Cully, D.F. (1991) Avermectin-sensitive chloride currents induced by Caenorhabditis elegans RNA in Xenopus oocytes. Mol. Pharmacol., 40, 368-374.
    • (1991) Mol. Pharmacol. , vol.40 , pp. 368-374
    • Arena, J.P.1    Liu, K.K.2    Paress, P.S.3    Cully, D.F.4
  • 75
    • 0001948024 scopus 로고
    • Mode of action of ivermectin
    • (ed. W.C. Campbell), Springer, New York
    • Turner, M.J. and Schaeffer, J.M. (1989) Mode of action of ivermectin, in Ivermectin and Abamectin (ed. W.C. Campbell), Springer, New York, pp. 73-88.
    • (1989) Ivermectin and Abamectin , pp. 73-88
    • Turner, M.J.1    Schaeffer, J.M.2
  • 76
    • 79952678169 scopus 로고    scopus 로고
    • Recent progress in understanding the interaction between avermectins and ligand-gated ion channels: putting the pests to sleep
    • Wolstenholme, A. (2010) Recent progress in understanding the interaction between avermectins and ligand-gated ion channels: putting the pests to sleep. Invert. Neurosci., 10, 5-10.
    • (2010) Invert. Neurosci. , vol.10 , pp. 5-10
    • Wolstenholme, A.1
  • 77
    • 0030824367 scopus 로고    scopus 로고
    • avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans
    • Dent, J.A., Davis, M.W., and Avery, L. (1997) avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans. EMBO J., 16, 5867-5879.
    • (1997) EMBO J , vol.16 , pp. 5867-5879
    • Dent, J.A.1    Davis, M.W.2    Avery, L.3
  • 78
    • 0035034536 scopus 로고    scopus 로고
    • Characterization of glutamate-gated chloride channels in the pharynx of wildtype and mutant Caenorhabditis elegans delineates the role of the subunit GluClalpha2 in the function of the native receptor
    • Pemberton, D., Franks, C., Walker, R., and Holden-Dye, L. (2001) Characterization of glutamate-gated chloride channels in the pharynx of wildtype and mutant Caenorhabditis elegans delineates the role of the subunit GluClalpha2 in the function of the native receptor. Mol. Pharmacol., 59, 1037-1043.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 1037-1043
    • Pemberton, D.1    Franks, C.2    Walker, R.3    Holden-Dye, L.4
  • 79
    • 0034646245 scopus 로고    scopus 로고
    • The genetics of ivermectin resistance in Caenorhabditis elegans
    • Dent, J., Smith, M., Vassilatis, D., and Avery, L. (2000) The genetics of ivermectin resistance in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA, 97, 2674-2679.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2674-2679
    • Dent, J.1    Smith, M.2    Vassilatis, D.3    Avery, L.4
  • 80
    • 33645881686 scopus 로고    scopus 로고
    • Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors
    • Cook, A., Aptel, N., Portillo, V., Siney, E., Sihota, R., Holden-Dye, L., and Wolstenholme, A. (2006) Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors. Mol. Biochem. Parasitol., 147, 118-125.
    • (2006) Mol. Biochem. Parasitol. , vol.147 , pp. 118-125
    • Cook, A.1    Aptel, N.2    Portillo, V.3    Siney, E.4    Sihota, R.5    Holden-Dye, L.6    Wolstenholme, A.7
  • 81
    • 33646586086 scopus 로고    scopus 로고
    • Actions of glutamate and ivermectin on the pharyngeal muscle of Ascaridia galli: a comparative study with Caenorhabditis elegans
    • Holden-Dye, L. and Walker, R.J. (2006) Actions of glutamate and ivermectin on the pharyngeal muscle of Ascaridia galli: a comparative study with Caenorhabditis elegans. Int. J. Parasitol., 36, 395-402.
    • (2006) Int. J. Parasitol. , vol.36 , pp. 395-402
    • Holden-Dye, L.1    Walker, R.J.2
  • 83
    • 0030856256 scopus 로고    scopus 로고
    • Actions of the anthelmintic ivermectin on the pharyngeal muscle of the parasitic nematode
    • Brownlee, D.J., Holden-Dye, L., and Walker, R.J. (1997) Actions of the anthelmintic ivermectin on the pharyngeal muscle of the parasitic nematode, Ascaris suum. Parasitology, 115, 553-561.
    • (1997) Ascaris suum. Parasitology , vol.115 , pp. 553-561
    • Brownlee, D.J.1    Holden-Dye, L.2    Walker, R.J.3
  • 84
    • 57649087686 scopus 로고    scopus 로고
    • Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans
    • James, C.E. and Davey, M.W. (2009) Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans. Int. J. Parasitol., 39, 213-220.
    • (2009) Int. J. Parasitol. , vol.39 , pp. 213-220
    • James, C.E.1    Davey, M.W.2
  • 85
    • 0035348158 scopus 로고    scopus 로고
    • Latrophilin-like receptor from the parasitic nematodeHaemonchus contortus as target for the anthelmintic depsipeptide PF1022A
    • Saeger, B., Schmitt-Wrede, H.-P., Dehnhardt, M., Benten, W.P.M., Krücken, J., Harder, A., von Samson-Himmelstjerna, G. et al. (2001) Latrophilin-like receptor from the parasitic nematodeHaemonchus contortus as target for the anthelmintic depsipeptide PF1022A. FASEB J., 15, 1332-1334.
    • (2001) FASEB J , vol.15 , pp. 1332-1334
    • Saeger, B.1    Schmitt-Wrede, H.-P.2    Dehnhardt, M.3    Benten, W.P.M.4    Krücken, J.5    Harder, A.6    von Samson-Himmelstjerna, G.7
  • 86
    • 4143086112 scopus 로고    scopus 로고
    • Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans
    • Willson, J., Amliwala, K., Davis, A., Cook, A., Cuttle, M.F., Kriek, N., Hopper, N.A., O'Connor, V. et al. (2004) Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans. Curr. Biol., 14, 1374-1379.
    • (2004) Curr. Biol. , vol.14 , pp. 1374-1379
    • Willson, J.1    Amliwala, K.2    Davis, A.3    Cook, A.4    Cuttle, M.F.5    Kriek, N.6    Hopper, N.A.7    O'Connor, V.8
  • 87
    • 33745657466 scopus 로고    scopus 로고
    • Evolution of pharyngeal behaviors and neuronal functions in freeliving soil nematodes
    • Chiang, J., Steciuk, M., Shtonda, B., and Avery, L. (2006) Evolution of pharyngeal behaviors and neuronal functions in freeliving soil nematodes. J. Exp. Biol., 209, 1859-1873.
    • (2006) J. Exp. Biol. , vol.209 , pp. 1859-1873
    • Chiang, J.1    Steciuk, M.2    Shtonda, B.3    Avery, L.4
  • 88
    • 0035819056 scopus 로고    scopus 로고
    • SLO-1 potassium channels control quantal content of neurotransmitter release at the C. elegans neuromuscular junction
    • Wang, Z.-W., Saifee, O., Nonet, M.L., and Salkoff, L. (2001) SLO-1 potassium channels control quantal content of neurotransmitter release at the C. elegans neuromuscular junction. Neuron, 32, 867-881.
    • (2001) Neuron , vol.32 , pp. 867-881
    • Wang, Z.-W.1    Saifee, O.2    Nonet, M.L.3    Salkoff, L.4
  • 89
    • 79956336717 scopus 로고    scopus 로고
    • Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans
    • Crisford, A., Murray, C., O.Connor, V., Edwards, R.J., Kruger, N., Welz, C., von Samson-Himmelstjerna, G. et al. (2011) Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans. Mol. Pharmacol., 79, 1031-1043.
    • (2011) Mol. Pharmacol. , vol.79 , pp. 1031-1043
    • Crisford, A.1    Murray, C.2    O'Connor, V.3    Edwards, R.J.4    Kruger, N.5    Welz, C.6    von Samson-Himmelstjerna, G.7
  • 90
    • 80052250730 scopus 로고    scopus 로고
    • On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum
    • Buxton, S.K., Neveu, C., Charvet, C.L., Robertson, A.P., and Martin, R.J. (2011) On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum. Br. J. Pharmacol., 164, 453-470.
    • (2011) Br. J. Pharmacol. , vol.164 , pp. 453-470
    • Buxton, S.K.1    Neveu, C.2    Charvet, C.L.3    Robertson, A.P.4    Martin, R.J.5
  • 91
    • 79955750096 scopus 로고    scopus 로고
    • SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants
    • Welz, C., Krüger, N., Schniederjans, M., Miltsch, S.M., Krücken, J., Guest, M., Holden-Dye, L.M. et al. (2011) SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants. PLoS Pathog., 7, e1001330.
    • (2011) PLoS Pathog , vol.7
    • Welz, C.1    Krüger, N.2    Schniederjans, M.3    Miltsch, S.M.4    Krücken, J.5    Guest, M.6    Holden-Dye, L.M.7
  • 93
    • 34248593424 scopus 로고    scopus 로고
    • Identification of Heterodera glycines (soybean cyst nematode [SCN]) cDNA sequences with high identity to those of Caenorhabditis elegans having lethal mutant or RNAi phenotypes
    • Alkharouf, N.W., Klink, V.P., and Matthews, B.F. (2007) Identification of Heterodera glycines (soybean cyst nematode [SCN]) cDNA sequences with high identity to those of Caenorhabditis elegans having lethal mutant or RNAi phenotypes. Exp. Parasitol., 115, 247-258.
    • (2007) Exp. Parasitol. , vol.115 , pp. 247-258
    • Alkharouf, N.W.1    Klink, V.P.2    Matthews, B.F.3
  • 94
    • 29044433616 scopus 로고    scopus 로고
    • Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses
    • Nagel, G., Brauner, M., Liewald, J.F., Adeishvili, N., Bamberg, E., and Gottschalk, A. (2005) Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Curr. Biol., 15, 2279-2284.
    • (2005) Curr. Biol. , vol.15 , pp. 2279-2284
    • Nagel, G.1    Brauner, M.2    Liewald, J.F.3    Adeishvili, N.4    Bamberg, E.5    Gottschalk, A.6
  • 96
    • 62949249418 scopus 로고    scopus 로고
    • A comparison of electrically evoked and channel rhodopsin-evoked postsynaptic potentials in the pharyngeal system of Caenorhabditis elegans
    • Franks, C., Murray, C., Ogden, D., O'Connor, V., and Holden-Dye, L. (2009) A comparison of electrically evoked and channel rhodopsin-evoked postsynaptic potentials in the pharyngeal system of Caenorhabditis elegans. Invert. Neurosci., 9, 43-56.
    • (2009) Invert. Neurosci. , vol.9 , pp. 43-56
    • Franks, C.1    Murray, C.2    Ogden, D.3    O'Connor, V.4    Holden-Dye, L.5
  • 97
    • 0033680858 scopus 로고    scopus 로고
    • Optical imaging of calcium transients in neurons and pharyngeal muscle ofC. elegans
    • Kerr, R., Lev-Ram, V., Baird, G., Vincent, P., Tsien, R.Y., and Schafer,W.R. (2000) Optical imaging of calcium transients in neurons and pharyngeal muscle ofC. elegans. Neuron, 26, 583-594.
    • (2000) Neuron , vol.26 , pp. 583-594
    • Kerr, R.1    Lev-Ram, V.2    Baird, G.3    Vincent, P.4    Tsien, R.Y.5    Schafer, W.R.6
  • 99
    • 46249092235 scopus 로고    scopus 로고
    • Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans
    • Chung, K., Crane, M.M., and Lu, H. (2008) Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans. Nat. Methods, 5, 637-643.
    • (2008) Nat. Methods , vol.5 , pp. 637-643
    • Chung, K.1    Crane, M.M.2    Lu, H.3
  • 100
    • 77955057457 scopus 로고    scopus 로고
    • Highthroughput study of synaptic transmission at the neuromuscular junction enabled by optogenetics and microfluidics
    • Stirman, J.N., Brauner, M., Gottschalk, A., and Lu, H. (2010) Highthroughput study of synaptic transmission at the neuromuscular junction enabled by optogenetics and microfluidics. J. Neurosci. Methods, 191, 90-93.
    • (2010) J. Neurosci. Methods , vol.191 , pp. 90-93
    • Stirman, J.N.1    Brauner, M.2    Gottschalk, A.3    Lu, H.4
  • 102
    • 0034788468 scopus 로고    scopus 로고
    • Gene structure of the extracellular glutathione S-transferase from Onchocerca volvulus and its overexpression and promoter analysis in transgenic Caenorhabditis elegans
    • Krause, S., Sommer, A., Fischer, P., Brophy, P.M.,Walter, R.D., and Liebau, E. (2001) Gene structure of the extracellular glutathione S-transferase from Onchocerca volvulus and its overexpression and promoter analysis in transgenic Caenorhabditis elegans. Mol. Biochem. Parasitol., 117, 145-154.
    • (2001) Mol. Biochem. Parasitol. , vol.117 , pp. 145-154
    • Krause, S.1    Sommer, A.2    Fischer, P.3    Brophy, P.M.4    Walter, R.D.5    Liebau, E.6
  • 103
    • 0036860232 scopus 로고    scopus 로고
    • Abundant larval transcript-1 and -2 genes from Brugia malayi: diversity of genomic environments but conservation of 50 promoter sequences functional in Caenorhabditis elegans
    • Gomez-Escobar, N., Gregory, W.F., Britton, C., Murray, L., Corton, C., Hall, N., Daub, J. et al. (2002) Abundant larval transcript-1 and -2 genes from Brugia malayi: diversity of genomic environments but conservation of 50 promoter sequences functional in Caenorhabditis elegans. Mol. Biochem. Parasitol., 125, 59-71.
    • (2002) Mol. Biochem. Parasitol. , vol.125 , pp. 59-71
    • Gomez-Escobar, N.1    Gregory, W.F.2    Britton, C.3    Murray, L.4    Corton, C.5    Hall, N.6    Daub, J.7
  • 104
    • 63449100424 scopus 로고    scopus 로고
    • Functional characterisation of a cyst nematode acetylcholinesterase gene using Caenorhabditis elegans as a heterologous system
    • Costa, J.C., Lilley, C.J., Atkinson, H.J., and Urwin, P.E. (2009) Functional characterisation of a cyst nematode acetylcholinesterase gene using Caenorhabditis elegans as a heterologous system. Int. J. Parasitol., 39, 849-858.
    • (2009) Int. J. Parasitol. , vol.39 , pp. 849-858
    • Costa, J.C.1    Lilley, C.J.2    Atkinson, H.J.3    Urwin, P.E.4


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