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Volumn , Issue , 2012, Pages 159-179

Quantitative High-Content Screening-Based Drug Discovery against Helmintic Diseases

Author keywords

Drug discovery; Filariasis; High content screening; High throughput screening; Phenotyping; Schistosomiasis

Indexed keywords


EID: 84886110168     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527652969.ch10     Document Type: Chapter
Times cited : (3)

References (64)
  • 1
    • 34548126499 scopus 로고    scopus 로고
    • Chemotherapy of schistosomiasis: present and future
    • Caffrey, C.R. (2007) Chemotherapy of schistosomiasis: present and future. Curr. Opin. Chem. Biol., 11, 433-439.
    • (2007) Curr. Opin. Chem. Biol. , vol.11 , pp. 433-439
    • Caffrey, C.R.1
  • 2
    • 33750508142 scopus 로고    scopus 로고
    • Schistosomiasis: challenges for control, treatment and drug resistance
    • Fenwick, A. and Webster, J.P. (2006) Schistosomiasis: challenges for control, treatment and drug resistance. Curr. Opin. Infect. Dis., 19, 577-582.
    • (2006) Curr. Opin. Infect. Dis. , vol.19 , pp. 577-582
    • Fenwick, A.1    Webster, J.P.2
  • 3
    • 33745657253 scopus 로고    scopus 로고
    • Ablueprint for success: integration of neglected tropical disease control programmes
    • Lammie, P.J., Fenwick, A., and Utzinger, J. (2006)Ablueprint for success: integration of neglected tropical disease control programmes. Trends Parasitol., 22, 313-321.
    • (2006) Trends Parasitol , vol.22 , pp. 313-321
    • Lammie, P.J.1    Fenwick, A.2    Utzinger, J.3
  • 4
    • 33745436655 scopus 로고    scopus 로고
    • Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk
    • Steinmann, P., Keiser, J., Bos, R., Tanner, M., and Utzinger, J. (2006) Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infect. Dis., 6, 411-425.
    • (2006) Lancet Infect. Dis. , vol.6 , pp. 411-425
    • Steinmann, P.1    Keiser, J.2    Bos, R.3    Tanner, M.4    Utzinger, J.5
  • 6
    • 70449568249 scopus 로고    scopus 로고
    • Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening
    • Abdulla, M.H., Ruelas, D.S., Wolff, B., Snedecor, J., Lim, K.C., Xu, F., Renslo, A.R. et al. (2009) Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening. PLoS Negl. Trop. Dis., 3, e478.
    • (2009) PLoS Negl. Trop. Dis. , vol.3
    • Abdulla, M.H.1    Ruelas, D.S.2    Wolff, B.3    Snedecor, J.4    Lim, K.C.5    Xu, F.6    Renslo, A.R.7
  • 7
    • 0037199261 scopus 로고    scopus 로고
    • Using Machine Vision to analyze and classify Caenorhabditis elegans behavioral phenotypes quantitatively
    • Baek, J.-H., Cosman, P., Feng, Z., Silver, J., and Schafer, W.R. (2002) Using Machine Vision to analyze and classify Caenorhabditis elegans behavioral phenotypes quantitatively. J. Neurosci. Methods, 118, 9-21.
    • (2002) J. Neurosci. Methods , vol.118 , pp. 9-21
    • Baek, J.-H.1    Cosman, P.2    Feng, Z.3    Silver, J.4    Schafer, W.R.5
  • 8
    • 4644232465 scopus 로고    scopus 로고
    • Automatic tracking, feature extraction and classification of C. elegans phenotypes
    • Geng, W., Cosman, P., Berry, C.C., Feng, Z., and Schafer, W.R. (2004) Automatic tracking, feature extraction and classification of C. elegans phenotypes. IEEE Trans. Biomed. Eng., 51, 1811-1820.
    • (2004) IEEE Trans. Biomed. Eng. , vol.51 , pp. 1811-1820
    • Geng, W.1    Cosman, P.2    Berry, C.C.3    Feng, Z.4    Schafer, W.R.5
  • 9
    • 0035949511 scopus 로고    scopus 로고
    • Behavioral screening for cocaine sensitivity in mutagenized zebrafish
    • USA
    • Darland, T. and Dowling, J.E. (2001) Behavioral screening for cocaine sensitivity in mutagenized zebrafish. Proc. Natl. Acad. Sci. USA, 98, 11691-11696.
    • (2001) Proc. Natl. Acad. Sci , vol.98 , pp. 11691-11696
    • Darland, T.1    Dowling, J.E.2
  • 10
    • 70349843025 scopus 로고    scopus 로고
    • Behavioral neuroscience of zebrafish
    • 2nd edn (ed. J.J.Buccafusco), CRC Press, Boca Raton, FL
    • Levin, E.D. and Cerutti, D.T. (2009)Behavioral neuroscience of zebrafish, Methods of Behavior Analysis in Neuroscience, 2nd edn (ed. J.J.Buccafusco), CRC Press, Boca Raton, FL. 291-308.
    • (2009) Methods of Behavior Analysis in Neuroscience , pp. 291-308
    • Levin, E.D.1    Cerutti, D.T.2
  • 11
    • 0030844195 scopus 로고    scopus 로고
    • Disruption of a behavioral sequence by targeted death of peptidergic neurons in Drosophila
    • McNabb, S.L., Baker, J.D., Agapite, J., Steller, H., Riddiford, L.M., and Truman, J.W. (1997) Disruption of a behavioral sequence by targeted death of peptidergic neurons in Drosophila. Neuron, 19, 813-823.
    • (1997) Neuron , vol.19 , pp. 813-823
    • McNabb, S.L.1    Baker, J.D.2    Agapite, J.3    Steller, H.4    Riddiford, L.M.5    Truman, J.W.6
  • 12
    • 63949088398 scopus 로고    scopus 로고
    • Automated monitoring and analysis of social behavior in drosophila
    • Dankert, H., Wang, L., Hoopfer, E.D., Anderson, D.J., and Perona, P. (2009) Automated monitoring and analysis of social behavior in drosophila. Nat. Methods, 6, 297-303.
    • (2009) Nat. Methods , vol.6 , pp. 297-303
    • Dankert, H.1    Wang, L.2    Hoopfer, E.D.3    Anderson, D.J.4    Perona, P.5
  • 13
    • 0032944075 scopus 로고    scopus 로고
    • Vomeronasal neuroepithelium and forebrain Fos responses to male pheromones in male and female mice
    • Halem, H.A., Cherry, J.A., and Baum, M.J. (1999) Vomeronasal neuroepithelium and forebrain Fos responses to male pheromones in male and female mice. J. Neurobiol., 39, 249-263.
    • (1999) J. Neurobiol. , vol.39 , pp. 249-263
    • Halem, H.A.1    Cherry, J.A.2    Baum, M.J.3
  • 14
    • 84886200255 scopus 로고    scopus 로고
    • IEEE International Workshop on Performance Evaluation of Tracking and Surveillance, Graz
    • Branson, K., Rabaud, W.R., and Belongie, S. (2003) Three brown mice: see how they run, IEEE International Workshop on Performance Evaluation of Tracking and Surveillance, Graz.
    • (2003) Three brown mice: see how they run
    • Branson, K.1    Rabaud, W.R.2    Belongie, S.3
  • 15
    • 5444248007 scopus 로고    scopus 로고
    • The biomechanical and neural control of hydrostatic limb movements in Manduca sexta
    • Mezoff, S., Papastathis, N., Takesian, A., and Trimmer, B.A. (2004) The biomechanical and neural control of hydrostatic limb movements in Manduca sexta. J. Exp. Biol., 17, 3043-3053.
    • (2004) J. Exp. Biol. , vol.17 , pp. 3043-3053
    • Mezoff, S.1    Papastathis, N.2    Takesian, A.3    Trimmer, B.A.4
  • 17
    • 33749068684 scopus 로고    scopus 로고
    • EigenPhenotypes: towards an algorithmic framework for phenotype discovery
    • Computational Systems Bioinformatics Conference, Stanford, CA
    • Vaughan, A., Singh, R., Shimoide, A., Yoon, I., and Fuse, M. (2005) EigenPhenotypes: towards an algorithmic framework for phenotype discovery, IEEE Computational Systems Bioinformatics Conference, Stanford, CA
    • (2005) IEEE
    • Vaughan, A.1    Singh, R.2    Shimoide, A.3    Yoon, I.4    Fuse, M.5
  • 18
    • 80052483092 scopus 로고    scopus 로고
    • Schistosomiasis: from drug deployment to drug development
    • Caffrey, C.R. and Secor, W.E. (2011) Schistosomiasis: from drug deployment to drug development. Curr. Opin. Infect. Dis., 24, 410-417.
    • (2011) Curr. Opin. Infect. Dis. , vol.24 , pp. 410-417
    • Caffrey, C.R.1    Secor, W.E.2
  • 19
    • 84890988241 scopus 로고    scopus 로고
    • Target identification and mechanism-based screening for anthelmintics: application of veterinary antiparasitic research programs to search for new antiparasitic drugs for human indications
    • (ed. P.M. Selzer), Wiley-VCH Verlag GmbH, Weinheim
    • Geary, TG.,Woods, D.J., Williams, T., and Nwaka, S. (2009) Target identification and mechanism-based screening for anthelmintics: application of veterinary antiparasitic research programs to search for new antiparasitic drugs for human indications. Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates, (ed. P.M. Selzer), Wiley-VCH Verlag GmbH, Weinheim. 3-15.
    • (2009) Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates , pp. 3-15
    • Geary, T.G.1    Woods, D.J.2    Williams, T.3    Nwaka, S.4
  • 20
    • 34447502161 scopus 로고    scopus 로고
    • Image based chemical screening
    • Carpenter, A. (2007) Image based chemical screening. Nat. Chem. Biol., 3, 461-465.
    • (2007) Nat. Chem. Biol. , vol.3 , pp. 461-465
    • Carpenter, A.1
  • 22
    • 74549174645 scopus 로고    scopus 로고
    • Introduction to the quantitative analysis of two dimensional fluorescence microscopy images for cell-based screening
    • Ljosa, V. and Carpenter, A. (2009) Introduction to the quantitative analysis of two dimensional fluorescence microscopy images for cell-based screening. PLoS Comp. Biol., 5, e1000603.
    • (2009) PLoS Comp. Biol. , vol.5
    • Ljosa, V.1    Carpenter, A.2
  • 23
    • 63749105759 scopus 로고    scopus 로고
    • Quantitative biological image analysis
    • (eds S. Shorte and F. Frischknecht), Springer, Berlin
    • Meijering, E. andVanCappellen, G. (2007) Quantitative biological image analysis. Imaging Cellular and Molecular Biological Function, (eds S. Shorte and F. Frischknecht), Springer, Berlin. 45-70.
    • (2007) Imaging Cellular and Molecular Biological Function , pp. 45-70
    • Meijering, E.1    VanCappellen, G.2
  • 24
    • 50549104043 scopus 로고    scopus 로고
    • Bioimage informatics: a new area of engineering biology
    • Peng, H. (2008) Bioimage informatics: a new area of engineering biology. Bioinformatics, 24, 1827-1836.
    • (2008) Bioinformatics , vol.24 , pp. 1827-1836
    • Peng, H.1
  • 25
    • 74549167655 scopus 로고    scopus 로고
    • The management of chemical and biological information
    • Chung, T.D. (2008) The management of chemical and biological information. Curr. Opin. Drug Discov. Dev., 11, 299-300.
    • (2008) Curr. Opin. Drug Discov. Dev. , vol.11 , pp. 299-300
    • Chung, T.D.1
  • 26
    • 84911837213 scopus 로고
    • Communication in the presence of noise
    • Shannon, C.E. (1949) Communication in the presence of noise. Proc. Inst. Radio Eng., 37, 10-21.
    • (1949) Proc. Inst. Radio Eng. , vol.37 , pp. 10-21
    • Shannon, C.E.1
  • 27
    • 33846013241 scopus 로고    scopus 로고
    • Object tracking: a survey
    • doi: 10.1145/
    • Yilmaz, A., Javed, O., and Shah, M. (2006) Object tracking: a survey. ACM Comput. Surv., 38, article 13; doi: 10.1145/ 1177352.1177355
    • (2006) ACM Comput. Surv. , vol.38
    • Yilmaz, A.1    Javed, O.2    Shah, M.3
  • 28
    • 0036565814 scopus 로고    scopus 로고
    • Mean shift: a robust approach towards feature space analysis
    • Comaniciu, D. and Meer, P. (2002) Mean shift: a robust approach towards feature space analysis. IEEE Trans. Pattern Anal. Mach. Intell., 24, 603-619.
    • (2002) IEEE Trans. Pattern Anal. Mach. Intell. , vol.24 , pp. 603-619
    • Comaniciu, D.1    Meer, P.2
  • 29
  • 31
    • 70449652432 scopus 로고    scopus 로고
    • Automated image-based phenotypic screening for high-throughput drug discovery
    • Symposium on Computer-Based Medical Systems, Albuquerque, NM
    • Singh, R., Pittas, M., Heskia, I., Xu, F., McKerrow, J.H., and Caffrey, C.R. (2009) Automated image-based phenotypic screening for high-throughput drug discovery. IEEE, Symposium on Computer-Based Medical Systems, Albuquerque, NM.
    • (2009) IEEE
    • Singh, R.1    Pittas, M.2    Heskia, I.3    Xu, F.4    McKerrow, J.H.5    Caffrey, C.R.6
  • 32
    • 33751510756 scopus 로고    scopus 로고
    • Nuclei segmentation using markercontrolled watershed, tracking using mean-shift, and Kalman filter in timelapse microscopy
    • Yang, X., Li, H., and Zhou, X. (2006) Nuclei segmentation using markercontrolled watershed, tracking using mean-shift, and Kalman filter in timelapse microscopy. IEEE Trans. Circuits Syst., 53, 2405-2414.
    • (2006) IEEE Trans. Circuits Syst. , vol.53 , pp. 2405-2414
    • Yang, X.1    Li, H.2    Zhou, X.3
  • 34
    • 23944488850 scopus 로고    scopus 로고
    • Tracking movement in cell biology
    • Miura, K. (2005) Tracking movement in cell biology. Adv. Biochem. Eng. Biotechnol., 95, 267-295.
    • (2005) Adv. Biochem. Eng. Biotechnol. , vol.95 , pp. 267-295
    • Miura, K.1
  • 35
    • 38249019393 scopus 로고
    • Quantification of tissue sections: graph theory and topology as modelling tools
    • Rodenacker, K. and Bischoff, P. (1990) Quantification of tissue sections: graph theory and topology as modelling tools. Pattern Recogn. Lett., 11, 275-284.
    • (1990) Pattern Recogn. Lett. , vol.11 , pp. 275-284
    • Rodenacker, K.1    Bischoff, P.2
  • 38
    • 0028464661 scopus 로고
    • Topographic distance and watershed lines
    • Meyer, F. (1994) Topographic distance and watershed lines. Signal Process., 38, 113-125.
    • (1994) Signal Process , vol.38 , pp. 113-125
    • Meyer, F.1
  • 39
    • 0026172104 scopus 로고
    • Watersheds in digital spaces: an efficient algorithm based on immersion simulations
    • Vincent, L. and Soille, P. (1991) Watersheds in digital spaces: an efficient algorithm based on immersion simulations. IEEE Trans. Pattern Anal. and Mach. Intell., 13, 583-598.
    • (1991) IEEE Trans. Pattern Anal. and Mach. Intell. , vol.13 , pp. 583-598
    • Vincent, L.1    Soille, P.2
  • 40
    • 0035400763 scopus 로고    scopus 로고
    • An efficient method based on watershed and rule-based merging for segmentation of 3-D histo-pathological images
    • Adiga, P.S.U. and Chaudhuri, B.B. (2001) An efficient method based on watershed and rule-based merging for segmentation of 3-D histo-pathological images. Pattern Recognit., 34, 1449-1458.
    • (2001) Pattern Recognit , vol.34 , pp. 1449-1458
    • Adiga, P.S.U.1    Chaudhuri, B.B.2
  • 41
    • 47049102271 scopus 로고    scopus 로고
    • CellTrack: an open-source software for cell tracking and motility analysis
    • Sacan, A., Ferhatosmanoglu, H., and Coskun, H. (2008) CellTrack: an open-source software for cell tracking and motility analysis. Bioinformatics, 24, 1647-1649.
    • (2008) Bioinformatics , vol.24 , pp. 1647-1649
    • Sacan, A.1    Ferhatosmanoglu, H.2    Coskun, H.3
  • 43
    • 0036826171 scopus 로고    scopus 로고
    • Tracking leukocytes in vivo with shape and size constrained active contours
    • Ray, N., Acton, S.T., and Ley, K. (2002) Tracking leukocytes in vivo with shape and size constrained active contours. IEEE Trans.Med. Imaging, 21, 1222-1235.
    • (2002) IEEE Trans. Med. Imaging , vol.21 , pp. 1222-1235
    • Ray, N.1    Acton, S.T.2    Ley, K.3
  • 45
    • 0036826342 scopus 로고    scopus 로고
    • Segmentation and tracking of migrating cells in videomicroscopy with parametric active contours: a tool for cell-based drug testing
    • Zimmer, C., Labruyére, E.,Meas-Yedid,V., Guillén, N., and Olivo-Marin, J.C. (2002) Segmentation and tracking of migrating cells in videomicroscopy with parametric active contours: a tool for cell-based drug testing. IEEE Trans. Med. Imaging, 21, 1212-1221.
    • (2002) IEEE Trans. Med. Imaging , vol.21 , pp. 1212-1221
    • Zimmer, C.1    Labruyére, E.2    Meas-Yedid, V.3    Guillén, N.4    Olivo-Marin, J.C.5
  • 46
    • 1942532718 scopus 로고    scopus 로고
    • Level set analysis for leukocyte detection and tracking
    • Mukherjee, D.P., Ray, N., and Acton, S.T. (2004) Level set analysis for leukocyte detection and tracking. IEEE Trans. Image Process., 13, 562-572.
    • (2004) IEEE Trans. Image Process. , vol.13 , pp. 562-572
    • Mukherjee, D.P.1    Ray, N.2    Acton, S.T.3
  • 48
    • 36248952691 scopus 로고    scopus 로고
    • Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
    • Hill, A.A., LaPan, P., Li, Y., and Haney, S. (2007) Impact of image segmentation on high-content screening data quality for SK-BR-3 cells. BMC Bioinformatics, 8, 340.
    • (2007) BMC Bioinformatics , vol.8 , pp. 340
    • Hill, A.A.1    LaPan, P.2    Li, Y.3    Haney, S.4
  • 50
    • 69049117343 scopus 로고    scopus 로고
    • Fast automated measurement of nematode swimming (thrashing) without morphometry
    • Buckingham, S.D. and Sattelle, D.B. (2009) Fast automated measurement of nematode swimming (thrashing) without morphometry. BMC Neurosci., 10, 84.
    • (2009) BMC Neurosci , vol.10 , pp. 84
    • Buckingham, S.D.1    Sattelle, D.B.2
  • 52
    • 0347622772 scopus 로고    scopus 로고
    • Quantitative classification and natural clustering of Caenorhabditis elegans behavioral phenotypes
    • Geng, W., Cosman, P., Baek, J.H., Berry, C.C., and Schafer, W.R. (2003) Quantitative classification and natural clustering of Caenorhabditis elegans behavioral phenotypes. Genetics, 165, 1117-1126.
    • (2003) Genetics , vol.165 , pp. 1117-1126
    • Geng, W.1    Cosman, P.2    Baek, J.H.3    Berry, C.C.4    Schafer, W.R.5
  • 53
    • 62349136829 scopus 로고    scopus 로고
    • Using articulated models for tracking multiple C. elegans in physical contact
    • Huang, K., Cosman, P., and Schafer,W.R. (2009) Using articulated models for tracking multiple C. elegans in physical contact. J. Signal Process. Syst., 55, 113-126.
    • (2009) J. Signal Process. Syst. , vol.55 , pp. 113-126
    • Huang, K.1    Cosman, P.2    Schafer, W.R.3
  • 54
    • 34548829888 scopus 로고    scopus 로고
    • A computational model for C. elegans locomotory behavior: application to multiworm tracking
    • Roussel, N., Morton, C.A., Finger, F.P., and Roysam, B. (2007) A computational model for C. elegans locomotory behavior: application to multiworm tracking. IEEE Trans. Biomed. Eng., 54, 1786-1797.
    • (2007) IEEE Trans. Biomed. Eng. , vol.54 , pp. 1786-1797
    • Roussel, N.1    Morton, C.A.2    Finger, F.P.3    Roysam, B.4
  • 57
    • 0018306059 scopus 로고
    • A threshold selection method from gray-level histograms
    • Otsu, N. (1979) A threshold selection method from gray-level histograms. IEEE Trans. Syst. Man. Cybernet., 9, 62-66.
    • (1979) IEEE Trans. Syst. Man. Cybernet. , vol.9 , pp. 62-66
    • Otsu, N.1
  • 58
    • 80053346082 scopus 로고    scopus 로고
    • Region-based segmentation of parasites for highthroughput screening
    • Moody-Davis, A., Mennillo, L., and Singh, R. (2011) Region-based segmentation of parasites for highthroughput screening. Lect. Notes Comput. Sci., 6938, 44-54.
    • (2011) Lect. Notes Comput. Sci. , vol.6938 , pp. 44-54
    • Moody-Davis, A.1    Mennillo, L.2    Singh, R.3
  • 59
    • 21644463503 scopus 로고    scopus 로고
    • Real-time foreground-background segmentation using codebook model
    • Kim, K., Chalidabhongse, T.H., Harwood, D., and Davis, L. (2005) Real-time foreground-background segmentation using codebook model. Real-Time Imaging, 11, 172-185.
    • (2005) Real-Time Imaging , vol.11 , pp. 172-185
    • Kim, K.1    Chalidabhongse, T.H.2    Harwood, D.3    Davis, L.4
  • 60
    • 0035423154 scopus 로고    scopus 로고
    • Unsupervised segmentation of colortexture regions in images and video
    • Deng, Y. and Manjunath, B. (2001) Unsupervised segmentation of colortexture regions in images and video. IEEE Trans. Pattern Anal. Mach. Intell., 23, 800-810.
    • (2001) IEEE Trans. Pattern Anal. Mach. Intell. , vol.23 , pp. 800-810
    • Deng, Y.1    Manjunath, B.2


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