New insights into the mechanism underlying the synergistic action of ionizing radiation with platinum chemotherapeutic drugs: The role of low-energy electrons

International Journal of Radiation Oncology Biology Physics

Volumn 87, Issue 4, 2013, Pages 847-853

  Rezaee, Mohammad ^a   Hunting, Darel John ^a   Sanche, Léon ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTHERAPEUTIC DRUGS; DOUBLE-STRAND BREAKS; GEL ELECTROPHORESIS; HIGHER EFFICIENCY; LOW ENERGY ELECTRONS; METHODS AND MATERIALS; RADIO-SENSITIZATION; SYNERGISTIC ACTION;

BIOMOLECULES; DNA; ELECTRONS; ELECTROPHORESIS; IONIZING RADIATION; PLATINUM COMPOUNDS; RADIATION SHIELDING;

PLATINUM;

CARBOPLATIN; CELL NUCLEUS DNA; CISPLATIN; OXALIPLATIN; PLASMID DNA; RADIOSENSITIZING AGENT;

ARTICLE; CHEMORADIOTHERAPY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; DRUG EXPOSURE; DRUG SENSITIZATION; ELECTRON; ENERGY; GEL ELECTROPHORESIS; IONIZING RADIATION; LOW ENERGY ELECTRON; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOSENSITIVITY; RADIOSENSITIZATION;

ANTINEOPLASTIC AGENTS; CARBOPLATIN; CISPLATIN; DNA ADDUCTS; DNA DAMAGE; DNA, SUPERHELICAL; ELECTRONS; ORGANOPLATINUM COMPOUNDS; PLASMIDS; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS;

EID: 84886101848     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.06.2037     Document Type: Article

References (20)

1. T.Y. Seiwert, J.K. Salama, and E.E. Vokes The concurrent chemoradiation paradigm - general principles Nat Clin Pract Oncol 4 2007 86 100
2. L. Kelland The resurgence of platinum-based cancer chemotherapy Nat Rev Cancer 7 2007 573 584
3. D. Wang, and S.J. Lippard Cellular processing of platinum anticancer drugs Nat Rev Drug Discov 4 2005 307 320
4. Y. Jung, and S.J. Lippard Direct cellular responses to platinum-induced DNA damage Chem Rev 107 2007 1387 1407
5. G.D. Wilson, S.M. Bentzen, and P.M. Harari Biologic basis for combining drugs with radiation Semin Radiat Oncol 16 2006 2 9
6. S.M. Pimblott, and J.A. LaVerne Production of low-energy electrons by ionizing radiation Radiat Phys Chem 76 2007 1244 1247
7. L. Sanche Low-energy electron interaction with DNA: Bond dissociation and formation of transient anions, radicals, and radical anions M.M. Greenberg, Radical and Radical Ion Reactivity 2009 John Wiley & Sons Hoboken, NJ 239 294
8. M. Rezaee, L. Sanche, and D.J. Hunting Cisplatin enhances the formation of DNA single- and double-strand breaks by hydrated electrons and hydroxyl radicals Radiat Res 179 2013 323 331
9. J. Kopyra, C. Koenig-Lehmann, and I. Bald A single slow electron triggers the loss of both chlorine atoms from the anticancer drug cisplatin: Implications for chemoradiation therapy Angew Chem Int Ed Engl 48 2009 7904 7907
10. J. Kuduk-Jaworska, H. Chojnacki, and J.J. Jański Non-empirical quantum chemical studies on electron transfer reactions in trans- and cis-diamminedichloroplatinum(II) complexes J Mol Modeling 17 2011 2411 2421
11. Q.B. Lu, S. Kalantari, and C. Wang Electron transfer reaction mechanism of cisplatin with DNA at the molecular level Mol Pharm 4 2007 624 628
12. Q.B. Lu Molecular reaction mechanisms of combination treatments of low-dose cisplatin with radiotherapy and photodynamic therapy J Med Chem 50 2007 2601 2604
13. Y. Zheng, D.J. Hunting, P. Ayotte, and L. Sanche Role of secondary low-energy electrons in the concomitant chemoradiation therapy of cancer Phys Rev Lett 100 2008 198101
14. M. Rezaee, E. Alizadeh, D.J. Hunting, and L. Senche DNA-platinum thin films for use in chemoradiation therapy studies Bioinorg Chem Appl 2012 2012 923914
15. R.C. Todd, and S.J. Lippard Inhibition of transcription by platinum antitumor compounds Metallomics 1 2009 280 291
16. J.M. Woynarowski, S. Faivre, and M.C.S. Herzig Oxaliplatin-induced damage of cellular DNA Mol Pharmacol 58 2000 920 927
17. B. Boudaïffa, P. Cloutier, and D. Hunting Resonant formation of DNA strand breaks by low-energy (3 to 20 eV) electrons Science 287 2000 1658 1660
18. L. Sanche Role of secondary low energy electrons in radiobiology and chemoradiation therapy of cancer Chem Phys Lett 474 2009 1 6
19. O. Vrána, V. Boudńy, and V. Brabec Superhelical torsion controls DNA interstrand crosslinking by antitumor cis- diamminedichloroplatinum(II) Nucleic Acids Res 24 1996 3918 3925
20. T. Boulikas, G.P. Stathopoulos, and N. Volakakis Systemic lipoplatin infusion results in preferential tumor uptake in human studies Anticancer Res 25 2005 3031 3040