Characterization and application of a nose-only exposure chamber for inhalation delivery of liposomal drugs and nucleic acids to mice

Journal of Aerosol Medicine and Pulmonary Drug Delivery

Volumn 26, Issue 6, 2013, Pages 345-354

  Mainelis, G ^a   Seshadri, S ^a   Garbuzenko, O B ^a   Han, T ^a   Wang, Z ^a   Minko, T ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Drug carrier systems; Exposure; Inhalation; Liposomes; Lung cancer; Nose only chamber; Pump and nonpump resistance

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DOXORUBICIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN BCL 2; SMALL INTERFERING RNA;

AEROSOL; AIRBORNE PARTICLE; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RETENTION; DRUG STABILITY; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VIVO STUDY; INHALATION; LIPOSOMAL DELIVERY; LUNG CANCER; MOUSE; NEBULIZER; NONHUMAN; NOSE; PARTICLE SIZE; TUMOR VOLUME;

ADMINISTRATION, INTRANASAL; AEROSOLS; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; DOXORUBICIN; DRUG DELIVERY SYSTEMS; EQUIPMENT DESIGN; GENE TRANSFER TECHNIQUES; HUMANS; INJECTIONS, INTRAVENOUS; LIPOSOMES; LUNG NEOPLASMS; MICE; MICE, NUDE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PARTICLE SIZE; RNA, SMALL INTERFERING; TIME FACTORS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84886092551     PISSN: 19412711     EISSN: 19412703     Source Type: Journal    
DOI: 10.1089/jamp.2011-0966     Document Type: Article

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