Assessing the reproducibility of quantitative in vivo confocal microscopy of corneal nerves in different corneal locations

Cornea

Volumn 32, Issue 10, 2013, Pages 1331-1338

  Kim, Gene ^a,b,c   Singleton, J Robinson ^d   Mifflin, Mark D ^a   Digre, Kathleen B ^a   Porzio, Michael T ^d   Smith, A Gordon ^d  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c Robert Cizik Eye Clinic   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Corneal nerves; In vivo confocal microscopy; Multiple different corneal locations

Indexed keywords

ADULT; AMBULATORY CARE; ARTICLE; COMPARATIVE STUDY; CONFOCAL LASER MICROSCOPY; CORNEA; CORRELATION COEFFICIENT; DENSITY; FEMALE; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; MALE; NORMAL HUMAN; OPTIC NERVE; PLOTS AND CURVES; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; ANATOMY AND HISTOLOGY; CONFOCAL MICROSCOPY; INNERVATION; NERVE FIBER; OBSERVER VARIATION; TRIGEMINAL NERVE;

ADULT; CORNEA; FEMALE; HEALTHY VOLUNTEERS; HUMANS; MALE; MICROSCOPY, CONFOCAL; NERVE FIBERS; OBSERVER VARIATION; REPRODUCIBILITY OF RESULTS; TRIGEMINAL NERVE;

EID: 84886092338     PISSN: 02773740     EISSN: 15364798     Source Type: Journal    
DOI: 10.1097/ICO.0b013e31829dd7f8     Document Type: Article

References (25)

1. Patel DV, McGhee CN. In vivo confocal microscopy of human corneal nerves in health, in ocular and systemic disease, and following corneal surgery: a review. Br J Ophthalmol. 2009;93:853-860.
2. Kobayashi A, Yokogawa H, Sugiyama K. In vivo laser confocal microscopy of Bowman's layer of the cornea. Ophthalmology. 2006;113:2203-2208.
3. Oliveira-Soto L, Efron N. Morphology of corneal nerves using confocal microscopy. Cornea. 2001;20:374-384.
4. Oliveira-Soto L, Efron N. Assessing the cornea by in vivo confocal microscopy. Clin Experiment Ophthalmol. 2003;31:83-84; author reply 84-86.
5. Srinivasan M. Fungal keratitis. Curr Opin Ophthalmol. 2004;15:321-327.
6. De Cillà S, Ranno S, Carini E, et al. Corneal subbasal nerves changes in patients with diabetic retinopathy: an in vivo confocal study. Invest Ophthalmol Vis Sci. 2009;50:5155-5158.
7. Stachs O, Zhivov A, Kraak R, et al. Structural-functional correlations of corneal innervation after LASIK and penetrating keratoplasty. J Refract Surg. 2010;26:159-167.
8. Hamrah P, Cruzat A, Dastjerdi MH, et al. Corneal sensation and subbasal nerve alterations in patients with herpes simplex keratitis: an in vivo confocal microscopy study. Ophthalmology. 2010;117:1930-1936.
9. Cruzat A, Pavan-Langston D, Hamrah P. In vivo confocal microscopy of corneal nerves: analysis and clinical correlation. Semin Ophthalmol. 2010;25:171-177.
10. Cruzat A, Witkin D, Baniasadi N, et al. Inflammation and the nervous system: the connection in the cornea in patients with infectious keratitis. Invest Ophthalmol Vis Sci. 2011;52:5136-5143.
11. Vaddavalli PK, Garg P, Sharma S, et al. Role of confocal microscopy in the diagnosis of fungal and acanthamoeba keratitis. Ophthalmology. 2011;118:29-35.
12. Ishida N, Rao GN, del Cerro M, et al. Corneal nerve alterations in diabetes mellitus. Arch Ophthalmol. 1984;102:1380-1384.
13. Wu T, Ahmed A, Bril V, et al. Variables associated with corneal confocal microscopy parameters in healthy volunteers: implications for diabetic neuropathy screening. Diabet Med. 2012;29:e297-e303.
14. Tavakoli M, Mitu-Pretorian M, Petropoulos IN, et al. Corneal confocal microscopy detects early nerve regeneration in diabetic neuropathy after simultaneous pancreas and kidney transplantation. Diabetes. 2013;62: 254-260.
15. Efron N, Edwards K, Roper N, et al. Repeatability of measuring corneal subbasal nerve fiber length in individuals with type 2 diabetes. Eye Contact Lens. 2010;36:245-248.
16. Patel DV, McGhee CN. In vivo confocal microscopy of corneal stromal nerves in patients with peripheral neuropathy. Arch Neurol. 2009;66: 1179-1180; author reply 1180.
17. Patel DV, McGhee CN. Laser scanning in vivo confocal microscopy demonstrating significant alteration of human corneal nerves following herpes zoster ophthalmicus. Arch Neurol. 2010;67:640-641.
18. Patel DV, McGhee CN. In vivo laser scanning confocal microscopy confirms that the human corneal sub-basal nerve plexus is a highly dynamic structure. Invest Ophthalmol Vis Sci. 2008;49:3409-3412.
19. Petropoulos IN, Manzoor T, Morgan P, et al. Repeatability of in vivo corneal confocal microscopy to quantify corneal nerve morphology. Cornea. 2013;32:e83-e89.
20. Patel DV, Tavakoli M, Craig JP, et al. Corneal sensitivity and slit scanning in vivo confocal microscopy of the subbasal nerve plexus of the normal central and peripheral human cornea. Cornea. 2009;28:735-740.
21. Rieth S, Engel F, Bühner E, et al. Comparison of data from the rostock cornea module of the Heidelberg retina tomograph, the oculus pentacam, and the endothelial cell microscope. Cornea. 2010;29:314-320.
22. Salvetat ML, Zeppieri M, Miani F, et al. Comparison between laser scanning in vivo confocal microscopy and noncontact specular microscopy in assessing corneal endothelial cell density and central corneal thickness. Cornea. 2011;30:754-759.
23. Tavakoli M, Marshall A, Banka S, et al. Corneal confocal microscopy detects small-fiber neuropathy in Charcot-Marie-Tooth disease type 1A patients. Muscle Nerve. 2012;46:698-704.
24. Hertz P, Bril V, Orszag A, et al. Reproducibility of in vivo corneal confocal microscopy as a novel screening test for early diabetic sensorimotor polyneuropathy. Diabet Med. 2011;28:1253-1260.
25. Patel DV, McGhee CN. Quantitative analysis of in vivo confocal microscopy images: a review. Surv Ophthalmol. 2013 [epub ahead of print].