메뉴 건너뛰기




Volumn 127, Issue 3, 2013, Pages 378-393

Unesterified docosahexaenoic acid is protective in neuroinflammation

Author keywords

neuroinflammation; unesterified docosahexaenoic acid

Indexed keywords

BRAIN PROTEIN; DOCOSAHEXAENOIC ACID; HYDROPEROXY DOCOSAHEXAENOIC ACID; NEUROPROTECTIN D1; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID;

EID: 84886086977     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12392     Document Type: Article
Times cited : (140)

References (56)
  • 1
    • 78650510200 scopus 로고    scopus 로고
    • Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications
    • Aid S., and, Bosetti F., (2011) Targeting cyclooxygenases-1 and -2 in neuroinflammation: therapeutic implications. Biochimie 93, 46-51.
    • (2011) Biochimie , vol.93 , pp. 46-51
    • Aid, S.1    Bosetti, F.2
  • 2
    • 23344439553 scopus 로고    scopus 로고
    • Docosahexaenoic acid: A positive modulator of Akt signaling in neuronal survival
    • Akbar M., Calderon F., Wen Z., and, Kim H. Y., (2005) Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival. Proc. Natl Acad. Sci. USA 102, 10858-10863.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 10858-10863
    • Akbar, M.1    Calderon, F.2    Wen, Z.3    Kim, H.Y.4
  • 3
    • 77749291973 scopus 로고    scopus 로고
    • Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood
    • Appleton K. M., Rogers P. J., and, Ness A. R., (2010) Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood. Am. J. Clin. Nutr. 91, 757-770.
    • (2010) Am. J. Clin. Nutr. , vol.91 , pp. 757-770
    • Appleton, K.M.1    Rogers, P.J.2    Ness, A.R.3
  • 5
    • 78651278778 scopus 로고    scopus 로고
    • Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites
    • Basselin M., Ramadan E., Chen M., and, Rapoport S. I., (2011) Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites. Neurochem. Res. 36, 139-145.
    • (2011) Neurochem. Res. , vol.36 , pp. 139-145
    • Basselin, M.1    Ramadan, E.2    Chen, M.3    Rapoport, S.I.4
  • 6
    • 67349173942 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale
    • Calder P. C., (2009) Polyunsaturated fatty acids and inflammatory processes: new twists in an old tale. Biochimie 91, 791-795.
    • (2009) Biochimie , vol.91 , pp. 791-795
    • Calder, P.C.1
  • 7
    • 79959973322 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids in Alzheimer's disease: Key questions and partial answers
    • Calon F., (2011) Omega-3 polyunsaturated fatty acids in Alzheimer's disease: key questions and partial answers. Curr. Alzheimer Res. 8, 470-478.
    • (2011) Curr. Alzheimer Res. , vol.8 , pp. 470-478
    • Calon, F.1
  • 8
    • 0003616161 scopus 로고
    • Canadian Council on Animal Care. Canadian Council on Animal Care, Ottawa.
    • Canadian Council on Animal Care (1993) Guide to the Care and use of Experimental Animals. Canadian Council on Animal Care, Ottawa.
    • (1993) Guide to the Care and Use of Experimental Animals
  • 9
    • 78651283588 scopus 로고    scopus 로고
    • Rapid de-esterification and loss of eicosapentaenoic acid from rat brain phospholipids: An intracerebroventricular study
    • Chen C. T., Liu Z., and, Bazinet R. P., (2011) Rapid de-esterification and loss of eicosapentaenoic acid from rat brain phospholipids: an intracerebroventricular study. J. Neurochem. 116, 363-373.
    • (2011) J. Neurochem. , vol.116 , pp. 363-373
    • Chen, C.T.1    Liu, Z.2    Bazinet, R.P.3
  • 10
    • 77953953898 scopus 로고    scopus 로고
    • Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid
    • Choi S. H., and, Bosetti F., (2009) Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid. Aging (Albany NY) 1, 234-244.
    • (2009) Aging (Albany NY) , vol.1 , pp. 234-244
    • Choi, S.H.1    Bosetti, F.2
  • 11
    • 43249109884 scopus 로고    scopus 로고
    • Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury
    • Choi S. H., Langenbach R., and, Bosetti F., (2008) Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide- induced inflammatory response and brain injury. FASEB J. 22, 1491-1501.
    • (2008) FASEB J. , vol.22 , pp. 1491-1501
    • Choi, S.H.1    Langenbach, R.2    Bosetti, F.3
  • 12
    • 78649411971 scopus 로고    scopus 로고
    • Dietary fatty acids and the aging brain
    • Cole G. M., Ma Q. L., and, Frautschy S. A., (2010) Dietary fatty acids and the aging brain. Nutr. Rev. 68 (Suppl 2), S102-S111.
    • (2010) Nutr. Rev. , vol.68 , Issue.SUPPL. 2
    • Cole, G.M.1    Ma, Q.L.2    Frautschy, S.A.3
  • 14
    • 9744284920 scopus 로고    scopus 로고
    • Half-lives of docosahexaenoic acid in rat brain phospholipids are prolonged by 15 weeks of nutritional deprivation of n-3 polyunsaturated fatty acids
    • DeMar J. C. Jr, Ma K., Bell J. M., and, Rapoport S. I., (2004) Half-lives of docosahexaenoic acid in rat brain phospholipids are prolonged by 15 weeks of nutritional deprivation of n-3 polyunsaturated fatty acids. J. Neurochem. 91, 1125-1137.
    • (2004) J. Neurochem. , vol.91 , pp. 1125-1137
    • Demar, Jr.J.C.1    Ma, K.2    Bell, J.M.3    Rapoport, S.I.4
  • 16
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J., Lees M., and, Sloane Stanley G. H., (1957) A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226, 497-509.
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 17
    • 33744811154 scopus 로고    scopus 로고
    • Uptake and metabolism of plasma-derived erucic acid by rat brain
    • Golovko M. Y., and, Murphy E. J., (2006) Uptake and metabolism of plasma-derived erucic acid by rat brain. J. Lipid Res. 47, 1289-1297.
    • (2006) J. Lipid Res. , vol.47 , pp. 1289-1297
    • Golovko, M.Y.1    Murphy, E.J.2
  • 18
    • 44949101603 scopus 로고    scopus 로고
    • An improved LC-MS/MS procedure for brain prostanoid analysis using brain fixation with head-focused microwave irradiation and liquid-liquid extraction
    • Golovko M. Y., and, Murphy E. J., (2008) An improved LC-MS/MS procedure for brain prostanoid analysis using brain fixation with head-focused microwave irradiation and liquid-liquid extraction. J. Lipid Res. 49, 893-902.
    • (2008) J. Lipid Res. , vol.49 , pp. 893-902
    • Golovko, M.Y.1    Murphy, E.J.2
  • 19
  • 20
    • 67650473883 scopus 로고    scopus 로고
    • Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid
    • He C., Qu X., Cui L., Wang J., and, Kang J. X., (2009) Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid. Proc. Natl Acad. Sci. USA 106, 11370-11375.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 11370-11375
    • He, C.1    Qu, X.2    Cui, L.3    Wang, J.4    Kang, J.X.5
  • 21
    • 69449093280 scopus 로고    scopus 로고
    • Toward optimizing vision and cognition in term infants by dietary docosahexaenoic and arachidonic acid supplementation: A review of randomized controlled trials
    • Hoffman D. R., Boettcher J. A., and, Diersen-Schade D. A., (2009) Toward optimizing vision and cognition in term infants by dietary docosahexaenoic and arachidonic acid supplementation: a review of randomized controlled trials. Prostaglandins Leukot. Essent. Fatty Acids 81, 151-158.
    • (2009) Prostaglandins Leukot. Essent. Fatty Acids , vol.81 , pp. 151-158
    • Hoffman, D.R.1    Boettcher, J.A.2    Diersen-Schade, D.A.3
  • 22
    • 0038013967 scopus 로고    scopus 로고
    • Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation
    • Hong S., Gronert K., Devchand P. R., Moussignac R. L., and, Serhan C. N., (2003) Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J. Biol. Chem. 278, 14677-14687.
    • (2003) J. Biol. Chem. , vol.278 , pp. 14677-14687
    • Hong, S.1    Gronert, K.2    Devchand, P.R.3    Moussignac, R.L.4    Serhan, C.N.5
  • 23
    • 33845972243 scopus 로고    scopus 로고
    • Resolvin D1, protectin D1, and related docosahexaenoic acid-derived products: Analysis via electrospray/low energy tandem mass spectrometry based on spectra and fragmentation mechanisms
    • Hong S., Lu Y., Yang R., Gotlinger K. H., Petasis N. A., and, Serhan C. N., (2007) Resolvin D1, protectin D1, and related docosahexaenoic acid-derived products: analysis via electrospray/low energy tandem mass spectrometry based on spectra and fragmentation mechanisms. J. Am. Soc. Mass Spectrom. 18, 128-144.
    • (2007) J. Am. Soc. Mass Spectrom. , vol.18 , pp. 128-144
    • Hong, S.1    Lu, Y.2    Yang, R.3    Gotlinger, K.H.4    Petasis, N.A.5    Serhan, C.N.6
  • 24
    • 35648944690 scopus 로고    scopus 로고
    • A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury
    • Huang W. L., King V. R., Curran O. E., Dyall S. C., Ward R. E., Lal N., Priestley J. V., and, Michael-Titus A. T., (2007) A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury. Brain 130, 3004-3019.
    • (2007) Brain , vol.130 , pp. 3004-3019
    • Huang, W.L.1    King, V.R.2    Curran, O.E.3    Dyall, S.C.4    Ward, R.E.5    Lal, N.6    Priestley, J.V.7    Michael-Titus, A.T.8
  • 25
    • 79851510275 scopus 로고    scopus 로고
    • Enduring prevention and transient reduction of postoperative pain by intrathecal resolvin D1
    • Huang L., Wang C. F., Serhan C. N., and, Strichartz G., (2011) Enduring prevention and transient reduction of postoperative pain by intrathecal resolvin D1. Pain 152, 557-565.
    • (2011) Pain , vol.152 , pp. 557-565
    • Huang, L.1    Wang, C.F.2    Serhan, C.N.3    Strichartz, G.4
  • 26
    • 1142310943 scopus 로고    scopus 로고
    • Transgenic mice: Fat-1 mice convert n-6 to n-3 fatty acids
    • Kang J. X., Wang J., Wu L., and, Kang Z. B., (2004) Transgenic mice: fat-1 mice convert n-6 to n-3 fatty acids. Nature 427, 504.
    • (2004) Nature , vol.427 , pp. 504
    • Kang, J.X.1    Wang, J.2    Wu, L.3    Kang, Z.B.4
  • 27
    • 58849111789 scopus 로고    scopus 로고
    • Rapid appearance of resolvin precursors in inflammatory exudates: Novel mechanisms in resolution
    • Kasuga K., Yang R., Porter T. F., Agrawal N., Petasis N. A., Irimia D., Toner M., and, Serhan C. N., (2008) Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. J. Immunol. 181, 8677-8687.
    • (2008) J. Immunol. , vol.181 , pp. 8677-8687
    • Kasuga, K.1    Yang, R.2    Porter, T.F.3    Agrawal, N.4    Petasis, N.A.5    Irimia, D.6    Toner, M.7    Serhan, C.N.8
  • 28
    • 79953043445 scopus 로고    scopus 로고
    • Altered arachidonic acid cascade enzymes in postmortem brain from bipolar disorder patients
    • Kim H. W., Rapoport S. I., and, Rao J. S., (2011a) Altered arachidonic acid cascade enzymes in postmortem brain from bipolar disorder patients. Mol. Psychiatry 16, 419-428.
    • (2011) Mol. Psychiatry , vol.16 , pp. 419-428
    • Kim, H.W.1    Rapoport, S.I.2    Rao, J.S.3
  • 30
    • 79951979686 scopus 로고    scopus 로고
    • Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions
    • Lafourcade M., Larrieu T., Mato S., et al,. (2011) Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. Nat. Neurosci. 14, 345-350.
    • (2011) Nat. Neurosci. , vol.14 , pp. 345-350
    • Lafourcade, M.1    Larrieu, T.2    Mato, S.3
  • 31
    • 80053309277 scopus 로고    scopus 로고
    • Accumulation of dietary docosahexaenoic acid in the brain attenuates acute immune response and development of postischemic neuronal damage
    • Lalancette-Hebert M., Julien C., Cordeau P., Bohacek I., Weng Y. C., Calon F., and, Kriz J., (2011) Accumulation of dietary docosahexaenoic acid in the brain attenuates acute immune response and development of postischemic neuronal damage. Stroke 42, 2903-2909.
    • (2011) Stroke , vol.42 , pp. 2903-2909
    • Lalancette-Hebert, M.1    Julien, C.2    Cordeau, P.3    Bohacek, I.4    Weng, Y.C.5    Calon, F.6    Kriz, J.7
  • 33
    • 0242290167 scopus 로고    scopus 로고
    • Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression
    • Marcheselli V. L., Hong S., Lukiw W. J., et al,. (2003) Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. J. Biol. Chem. 278, 43807-43817.
    • (2003) J. Biol. Chem. , vol.278 , pp. 43807-43817
    • Marcheselli, V.L.1    Hong, S.2    Lukiw, W.J.3
  • 34
    • 54849437276 scopus 로고    scopus 로고
    • Uncoupling of interleukin-6 from its signalling pathway by dietary n-3-polyunsaturated fatty acid deprivation alters sickness behaviour in mice
    • Mingam R., Moranis A., Bluthe R. M., De Smedt-Peyrusse V., Kelley K. W., Guesnet P., Lavialle M., Dantzer R., and, Laye S., (2008) Uncoupling of interleukin-6 from its signalling pathway by dietary n-3-polyunsaturated fatty acid deprivation alters sickness behaviour in mice. Eur. J. Neurosci. 28, 1877-1886.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 1877-1886
    • Mingam, R.1    Moranis, A.2    Bluthe, R.M.3    De Smedt-Peyrusse, V.4    Kelley, K.W.5    Guesnet, P.6    Lavialle, M.7    Dantzer, R.8    Laye, S.9
  • 35
    • 2942625603 scopus 로고    scopus 로고
    • Neuroprotectin D1: A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress
    • Mukherjee P. K., Marcheselli V. L., Serhan C. N., and, Bazan N. G., (2004) Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Proc. Natl Acad. Sci. USA 101, 8491-8496.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 8491-8496
    • Mukherjee, P.K.1    Marcheselli, V.L.2    Serhan, C.N.3    Bazan, N.G.4
  • 36
    • 77949492379 scopus 로고    scopus 로고
    • Brain fixation for analysis of brain lipid-mediators of signal transduction and brain eicosanoids requires head-focused microwave irradiation: An historical perspective
    • Murphy E. J., (2010) Brain fixation for analysis of brain lipid-mediators of signal transduction and brain eicosanoids requires head-focused microwave irradiation: an historical perspective. Prostaglandins Other Lipid Mediat. 91, 63-67.
    • (2010) Prostaglandins Other Lipid Mediat. , vol.91 , pp. 63-67
    • Murphy, E.J.1
  • 37
    • 77953288863 scopus 로고    scopus 로고
    • The fat-1 mouse has brain docosahexaenoic acid levels achievable through fish oil feeding
    • Orr S. K., Tong J. Y., Kang J. X., Ma D. W., and, Bazinet R. P., (2010) The fat-1 mouse has brain docosahexaenoic acid levels achievable through fish oil feeding. Neurochem. Res. 35, 811-819.
    • (2010) Neurochem. Res. , vol.35 , pp. 811-819
    • Orr, S.K.1    Tong, J.Y.2    Kang, J.X.3    Ma, D.W.4    Bazinet, R.P.5
  • 39
    • 33846540379 scopus 로고    scopus 로고
    • Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex
    • Rao J. S., Ertley R. N., DeMar J. C. Jr, Rapoport S. I., Bazinet R. P., and, Lee H. J., (2007a) Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex. Mol. Psychiatry 12, 151-157.
    • (2007) Mol. Psychiatry , vol.12 , pp. 151-157
    • Rao, J.S.1    Ertley, R.N.2    Demar, Jr.J.C.3    Rapoport, S.I.4    Bazinet, R.P.5    Lee, H.J.6
  • 40
    • 33845775752 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism
    • Rao J. S., Ertley R. N., Lee H. J., DeMar J. C. Jr, Arnold J. T., Rapoport S. I., and, Bazinet R. P., (2007b) n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. Mol. Psychiatry 12, 36-46.
    • (2007) Mol. Psychiatry , vol.12 , pp. 36-46
    • Rao, J.S.1    Ertley, R.N.2    Lee, H.J.3    Demar, Jr.J.C.4    Arnold, J.T.5    Rapoport, S.I.6    Bazinet, R.P.7
  • 43
    • 79955670124 scopus 로고    scopus 로고
    • Resolvins and protectins in inflammation resolution
    • Serhan C. N., and, Petasis N. A., (2011) Resolvins and protectins in inflammation resolution. Chem. Rev. 111, 5922-5943.
    • (2011) Chem. Rev. , vol.111 , pp. 5922-5943
    • Serhan, C.N.1    Petasis, N.A.2
  • 44
    • 0037152160 scopus 로고    scopus 로고
    • Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
    • Serhan C. N., Hong S., Gronert K., Colgan S. P., Devchand P. R., Mirick G., and, Moussignac R. L., (2002) Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med. 196, 1025-1037.
    • (2002) J. Exp. Med. , vol.196 , pp. 1025-1037
    • Serhan, C.N.1    Hong, S.2    Gronert, K.3    Colgan, S.P.4    Devchand, P.R.5    Mirick, G.6    Moussignac, R.L.7
  • 45
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
    • Serhan C. N., Chiang N., and, Van Dyke T. E., (2008) Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8, 349-361.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 47
  • 51
    • 70149123025 scopus 로고    scopus 로고
    • Resolvin D1 controls inflammation initiated by glutathione-lipid conjugates formed during oxidative stress
    • Spite M., Summers L., Porter T. F., Srivastava S., Bhatnagar A., and, Serhan C. N., (2009b) Resolvin D1 controls inflammation initiated by glutathione-lipid conjugates formed during oxidative stress. Br. J. Pharmacol. 158, 1062-1073.
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 1062-1073
    • Spite, M.1    Summers, L.2    Porter, T.F.3    Srivastava, S.4    Bhatnagar, A.5    Serhan, C.N.6
  • 52
    • 34248233132 scopus 로고    scopus 로고
    • Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation
    • Sun Y. P., Oh S. F., Uddin J., Yang R., Gotlinger K., Campbell E., Colgan S. P., Petasis N. A., and, Serhan C. N., (2007) Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation. J. Biol. Chem. 282, 9323-9334.
    • (2007) J. Biol. Chem. , vol.282 , pp. 9323-9334
    • Sun, Y.P.1    Oh, S.F.2    Uddin, J.3    Yang, R.4    Gotlinger, K.5    Campbell, E.6    Colgan, S.P.7    Petasis, N.A.8    Serhan, C.N.9
  • 53
    • 77952237425 scopus 로고    scopus 로고
    • Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions
    • 591p following 597.
    • Xu Z. Z., Zhang L., Liu T., Park J. Y., Berta T., Yang R., Serhan C. N., and, Ji R. R., (2010) Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat. Med. 16, 592-597; 591p following 597.
    • (2010) Nat. Med. , vol.16 , pp. 592-597
    • Xu, Z.Z.1    Zhang, L.2    Liu, T.3    Park, J.Y.4    Berta, T.5    Yang, R.6    Serhan, C.N.7    Ji, R.R.8
  • 54
    • 80052185387 scopus 로고    scopus 로고
    • Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes
    • Nov; Chapter 14, Unit 14.26.
    • Yang R., Chiang N., Oh S. F., and, Serhan C. N., (2011) Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes. Curr. Protoc. Immunol. Nov; Chapter 14, Unit 14.26.
    • (2011) Curr. Protoc. Immunol.
    • Yang, R.1    Chiang, N.2    Oh, S.F.3    Serhan, C.N.4
  • 55
    • 70349838221 scopus 로고    scopus 로고
    • Taking advantage of the systemic immune system to cure brain diseases
    • Yong V. W., and, Rivest S., (2009) Taking advantage of the systemic immune system to cure brain diseases. Neuron 64, 55-60.
    • (2009) Neuron , vol.64 , pp. 55-60
    • Yong, V.W.1    Rivest, S.2
  • 56
    • 79251559674 scopus 로고    scopus 로고
    • Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARgamma-mediated mechanisms in Alzheimer's disease models
    • Zhao Y., Calon F., Julien C., Winkler J. W., Petasis N. A., Lukiw W. J., and, Bazan N. G., (2011) Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARgamma-mediated mechanisms in Alzheimer's disease models. PLoS ONE 6, e15816.
    • (2011) PLoS ONE , vol.6
    • Zhao, Y.1    Calon, F.2    Julien, C.3    Winkler, J.W.4    Petasis, N.A.5    Lukiw, W.J.6    Bazan, N.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.