Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca2+ channels of colonic smooth muscle cells in rats

Phytomedicine

Volumn 20, Issue 14, 2013, Pages 1272-1279

  Zhang, Man ^a,b   Zang, Kai Hong ^a   Luo, Jia Lie ^a   Leung, Fung Ping ^a   Huang, Yu ^c   Lin, Cheng Yuan ^a   Yang, Zhi Jun ^a   Lu, Ai Ping ^a   Tang, Xu Dong ^a   Xu, Hong Xi ^d   Sung, Joseph Jao Yiu ^c   Bian, Zhao Xiang ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Colonic motility; L type Ca2+ channels; Magnolia officinalis; Magnolol; Smooth muscle cells

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ACETYLCHOLINE; CALCIUM CHANNEL L TYPE; MAGNOLOL; N(G) NITROARGININE METHYL ESTER; TETRODOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON MOTILITY; ELECTRIC POTENTIAL; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER;

MAGNOLIA OFFICINALIS; RATTUS;

5-HT; ACETYLCHOLINE; ACH; CARBACHOL; CCH; COLONIC MOTILITY; ENS; ENTERIC NERVOUS SYSTEM; L-NAME; L-TYPE CA(2+) CHANNELS; MAGNOLIA OFFICINALIS; MAGNOLOL; N(Ώ)-NITRO-L-ARGININE METHYL ESTER; NITRIC OXIDE; NO; SEROTONIN; SMOOTH MUSCLE CELLS; TETRODOTOXIN; TTX; VGCC; VOLTAGE-SENSITIVE CA(2+) CHANNELS;

ACETYLCHOLINE; ANIMALS; BIPHENYL COMPOUNDS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; COLON; DOWN-REGULATION; DRUGS, CHINESE HERBAL; LIGNANS; MAGNOLIA; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84886085070     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.07.008     Document Type: Article

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