Inhibition of myeloperoxidase decreases vascular oxidative stress and increases vasodilatation in sickle cell disease mice

Journal of Lipid Research

Volumn 54, Issue 11, 2013, Pages 3009-3015

  Zhang, Hao ^a   Xu, Hao ^a   Weihrauch, Dorothee ^a   Jones, Deron W ^a   Jing, Xigang ^a   Shi, Yang ^a,c   Gourlay, David ^a   Oldham, Keith T ^a   Hillery, Cheryl A ^a,b   Pritchard Jr , Kirkwood A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b BLOOD RESEARCH INSTITUTE   (United States)

^c Aurora Health Care   (United States)

Author keywords

Aorta; Chlorotyrosine; Endothelial cells; Facialis artery; L selectin; Liver; Malondialdehyde; Polymorphonuclear cells

Indexed keywords

3 CHLOROTYROSINASE; 3 NITROTYROSINE; ALANINE AMINOTRANSFERASE; ENZYME INHIBITOR; L SELECTIN; MALONALDEHYDE; MONOPHENOL MONOOXYGENASE; MYELOPEROXIDASE; N ACETYLLYSYLTYROSYLCYSTEINE AMIDE; UNCLASSIFIED DRUG; XANTHINE DEHYDROGENASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME BLOOD LEVEL; ENZYME INHIBITION; ENZYME RELEASE; FEMALE; HUMAN; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SICKLE CELL ANEMIA; VASODILATATION;

AORTA; CHLOROTYROSINE; ENDOTHELIAL CELLS; FACIALIS ARTERY; L-SELECTIN; LIVER; MALONDIALDEHYDE; POLYMORPHONUCLEAR CELLS;

ANEMIA, SICKLE CELL; ANIMALS; BLOOD VESSELS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENZYME INHIBITORS; FEMALE; HUMANS; HYPOCHLOROUS ACID; L-SELECTIN; LIVER; MALE; MICE; OLIGOPEPTIDES; OXIDATIVE STRESS; PEROXIDASE; SOLUBILITY; VASODILATION;

EID: 84886071622     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M038281     Document Type: Article

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