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Angewandte Chemie - International Edition

Volumn 52, Issue 44, 2013, Pages 11607-11611

Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase i inhibitor

(11) Funabashi, Masanori a Baba, Satoshi b Takatsu, Toshio b Kizuka, Masaaki a Ohata, Yasuo b Tanaka, Masahiro a Nonaka, Koichi b Spork, Anatol P c Ducho, Christian c Chen, Wei Chen Leyla d Van Lanen, Steven G d

a JAPAN SCIENCE AND TECHNOLOGY AGENCY (Japan)

b DAIICHI SANKYO CO (Japan)

c UNIVERSITY OF PADERBORN (Germany)

d University of Kentucky (United States)

Author keywords

actinomycetes; bacterial translocase I inhibitor; gene targeting; nucleoside antibiotics; transaldolase

Indexed keywords

ACTINOMYCETES; FERMENTATION OPTIMIZATIONS; GENE TARGETING; STRUCTURE-BASED; TRANSALDOLASE; TRANSLOCASES;

AMINO ACIDS; BACTERIA;

GENETIC ENGINEERING;

ANTIINFECTIVE AGENT; ENZYME INHIBITOR; TRANSALDOLASE;

ACTINOBACTERIA; ARTICLE; BACTERIAL TRANSLOCASE I INHIBITOR; CHEMISTRY; GENE TARGETING; METABOLISM; METHODOLOGY; NUCLEOSIDE ANTIBIOTICS;

ACTINOMYCETES; BACTERIAL TRANSLOCASE I INHIBITOR; GENE TARGETING; NUCLEOSIDE ANTIBIOTICS; TRANSALDOLASE;

ACTINOBACTERIA; ANTI-BACTERIAL AGENTS; ENZYME INHIBITORS; GENE TARGETING; TRANSALDOLASE;

EID: 84886070500 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201305546 Document Type: Article

Times cited : (27)

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