Modeling of the human rhinovirus C capsid suggests possible causes for antiviral drug resistance

Virology

Volumn 448, Issue , 2014, Pages 82-90

  Basta, Holly A ^a   Ashraf, Shamaila ^b   Sgro, Jean Yves ^a   Bochkov, Yury A ^b   Gern, James E ^b   Palmenberg, Ann C ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Antiviral therapy; Capsid structure; Drug resistance; Drug binding pocket; Model; Pleconaril; Pore; Rhinovirus; Rhinovirus C

Indexed keywords

3 METHYL 5 [7 [4 (4 METHYL 2 OXAZOLIN 2 YL)PHENOXY]HEPTYL]ISOXAZOLE; ANTIINFECTIVE AGENT; BTA 188; PLECONARIL; PROTEIN VP1; UNCLASSIFIED DRUG; WIN 52035; WIN 56291;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HYDROPHILICITY; MOLECULAR MODEL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RHINOVIRUS; SEQUENCE ALIGNMENT; SURFACE PROPERTY; VIRUS CAPSID;

EID: 84886056488     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.10.004     Document Type: Article

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