Analytical Methods for the Detection of Illicit Drugs in Wastewaters and Surface Waters

Illicit Drugs in the Environment: Occurrence, Analysis, and Fate Using Mass Spectrometry

Volumn , Issue , 2011, Pages 53-67

  Bagnati, Renzo ^a   Davoli, Enrico ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Mass spectrometry in illicit drugs' detection and measurement analytical methods for illicit drug detection in wastewaters and surface waters; Orbitrap MS, newly developed mass spectrometer high resolution, direct detection of illicit drugs in surface and wastewater samples; Sewage inlets and surface water analysis conventional HPLC MS MS approach and high resolution MS

Indexed keywords

EID: 84886032816     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118000816.ch3     Document Type: Chapter

References (23)

1. Bakhtiar, R., and T. K. Majumdar. 2007. Tracking problems and possible solutions in the quantitative determination of small molecule drugs and metabolites in biological fluids using liquid chromatography-mass spectrometry. J. Pharmacol. Toxicol. Methods 55:227-243.
2. Bijlsma, L., J. V. Sancho, E. Pitarch, M. Ibanez, and F. Hernandez, 2009. Simultaneous ultra-high-pressure liquid chromatography-tandem mass spectrometry determination of amphetamine and amphetamine-like stimulants, cocaine and its metabolites, and a cannabis metabolite in surface water and urban wastewater. J. Chromatogr. A 1216:3078-3089.
3. Boleda, R., T. Galceran, and F. Ventura. 2007. Trace determination of cannabinoids and opiates in wastewater and surface waters by ultra-performance liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 1175:38-48.
4. Bones, J., K. V. Thomas, and B. Paull. 2007. Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals. J. Environ. Monit. 9:701-707.
5. Castiglioni, S., E. Zuccato, E. Crisci, C. Chiabrando, R. Fanelli, and R. Bagnati. 2006. Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometry. Anal. Chem. 78:8421-8429.
6. Chiaia, A. C., C. Banta-Green, and J. Field. 2008. Eliminating solid phase extraction with large-volume injection LC/MS/MS: analysis of illicit and legal drugs and human urine indicators in US wastewaters. Environ. Sci. Technol. 42:8841-8848.
7. Davoli, E., S. Castiglioni, R. Bagnati, G. Bianchi, and R. Fanelli. 2008. Direct, trace level, environmental drug residues analysis by orbitrap MS. In Proceedings of the 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, CO.
8. Gheorghe, A., A. van Nuijs, B. Pecceu, L. Bervoets, P. G. Jorens, R. Blust, H. Neels, and A. Covaci. 2008. Analysis of cocaine and its principal metabolites in waste and surface water using solid-phase extraction and liquid chromatography-ion trap tandem mass spectrometry. Anal. Bioanal. Chem. 391:1309-1319.
9. Gupta, P. K., M. Hubbard, B. Gurley, and H. P. Hendrickson. 2009. Validation of a liquid chromatography-tandem mass spectrometric assay for the quantitative determination of hydrastine and berberine in human serum. J. Pharm. Biometric Anal. 49:1021-1026.
10. Hogenboom, A. C., J.A. van Leerdam, and P. deVoogt. Accurate mass screening and identification of emerging contaminants in environmental samples by liquid chromatography-hybrid linear ion trap Orbitrap mass spectrometry. J. Chromatogr. A 1216:510-519.
11. Huerta-Fontela, M.,M. T. Galceran, J. Martin-Alonso, and F. Ventura. 2007. Ultra-performance liquid chromatography-tandem mass spectrometry analysis of stimulatory drugs of abuse in wastewater and surface waters. Anal. Chem. 79:3821-3829.
12. Huestis, M. A., and M. L. Smith. 2006. Modern analytical technologies for the detection of drug abuse and doping. DDT 3:49-57.
13. Hummel, D., D. Loffler, G. Fink, and T. A. Ternes. 2006. Simultaneous determination of psychoactive drugs and their metabolites in aqueous matrices by liquid chromatography mass spectrometry. Environ. Sci. Technol. 40:7321-7328.
14. Kasprzyk-Hordern, B., R. M. Dinsdale, and A. J. Guwy. 2008. Multiresidue methods for the analysis of pharmaceuticals, personal care products and illicit drugs in surface water and wastewater by solid-phase extraction and ultra performance liquid chromatographyelectrospray tandem mass spectrometry. Anal. Bioanal. Chem. 391:1293-1308.
15. King, R., R. Bonfiglio, C. F. Metzler, C. Miller-Stein, and T. Olah. 2000. Mechanistic investigation of ionization suppression in electrospray ionization. J. Am. Soc. Mass Spectrom. 11:942-950.
16. Kjell, A. M., G. V. Alain, Z. Guo-Fang, and E. L. Willy. 2004. Enhanced method performance due to a shorter chromatographic run-time in a liquid chromatography-tandem mass spectrometry assay for paclitaxel. J. Chromatogr. A 1041:235-238.
17. Mari, F., L. Politi, A. Biggeri, G. Accetta, C. Trignano, M. Di Padua, and E. Bertol. 2009. Cocaine and heroin in waste water plants: a 1-year study in the city of Florence. Forensic Sci. Int. 198:88-92.
18. Mortier, K. A., K. E. Maudens, W. E. Lambert, K. M. Clauwaert, J. F. Van Bocxlaer, D. L. Deforce, C. H. Van Peteghem, and A. P. De Leenheera. 2002. Simultaneous, quantitative determination of opiates, amphetamines, cocaine and benzoylecgonine in oral fluid by liquid chromatography quadrupole-time-of-flight mass spectrometry. J. Chromatogr. B 779:321-330.
19. Nielena, M. W. F., M. C. van Engelena, R. Zuiderentb, and R. Ramakerc. 2007. Screening and confirmation criteria for hormone residue analysis using liquid chromatography accurate mass time-of-flight, Fourier transform ion cyclotron resonance and orbitrap mass spectrometry techniques. Anal. Chim. Acta 586:122-129.
20. Postigo, C., M. J. Lopez de Alda, and D. Barceló D. 2008. Fully automated determination in the low nanogram per liter level of different classes of drugs of abuse in sewage water by online solid-phase extraction-liquid chromatography-electrospray-tandem mass spectrometry. Anal. Chem. 80:3123-3134.
21. Postigo, C., M. J. Lopez de Alda, and D. Barceló. 2008. Analysis of drugs of abuse and their human metabolites in water by LC-MS2: A non-intrusive tool for drug abuse estimation at the community level. TrAC 27:1053-1069.
22. van Nuijs, A. L. N., I. Tarcomnicu, P. G. Jorens, L. Bervoets, R. Blust, H. Neels, and A. Covaci. 2009. Analysis of drugs of abuse in wastewater by hydrophilic interaction liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 395:819-828.
23. van Nuijs, A. L. N., S. Castiglioni, I. Tarcomnicu, C. Postigo, M. L. de Alda, H. Neels, E. Zuccato, D. Barceló, and A. Covaci A. 2010. Illicit drug consumption estimations derived from wastewater analysis: a critical review. Sci. Total Environ. 2010; in press. doi:10.1016/j.scitotenv.2010.05.030.