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Volumn 8, Issue 10, 2013, Pages

A Comprehensive Comparative Analysis of the Histomorphological Features of ALK-Rearranged Lung Adenocarcinoma Based on Driver Oncogene Mutations: Frequent Expression of Epithelial-Mesenchymal Transition Markers than Other Genotype

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; PROTEIN P40; PROTEIN P63; UVOMORULIN; VIMENTIN; PROTEIN TYROSINE KINASE;

EID: 84885996181     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076999     Document Type: Article
Times cited : (57)

References (33)
  • 1
    • 25644461068 scopus 로고    scopus 로고
    • International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising
    • Devesa SS, Bray F, Vizcaino AP, Parkin DM, (2005) International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. Int J Cancer 117: 294-299.
    • (2005) Int J Cancer , vol.117 , pp. 294-299
    • Devesa, S.S.1    Bray, F.2    Vizcaino, A.P.3    Parkin, D.M.4
  • 2
    • 36248980204 scopus 로고    scopus 로고
    • Characterizing the cancer genome in lung adenocarcinoma
    • Weir BA, Woo MS, Getz G, Perner S, Ding L, et al. (2007) Characterizing the cancer genome in lung adenocarcinoma. Nature 450: 893-898.
    • (2007) Nature , vol.450 , pp. 893-898
    • Weir, B.A.1    Woo, M.S.2    Getz, G.3    Perner, S.4    Ding, L.5
  • 3
    • 54549094903 scopus 로고    scopus 로고
    • Somatic mutations affect key pathways in lung adenocarcinoma
    • Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, et al. (2008) Somatic mutations affect key pathways in lung adenocarcinoma. Nature 455: 1069-1075.
    • (2008) Nature , vol.455 , pp. 1069-1075
    • Ding, L.1    Getz, G.2    Wheeler, D.A.3    Mardis, E.R.4    McLellan, M.D.5
  • 4
    • 22244436599 scopus 로고    scopus 로고
    • Female sex and bronchioloalveolar pathologic subtype predict EGFR mutations in non-small cell lung cancer
    • Hsieh RK, Lim KH, Kuo HT, Tzen CY, Huang MJ, (2005) Female sex and bronchioloalveolar pathologic subtype predict EGFR mutations in non-small cell lung cancer. Chest 128: 317-321.
    • (2005) Chest , vol.128 , pp. 317-321
    • Hsieh, R.K.1    Lim, K.H.2    Kuo, H.T.3    Tzen, C.Y.4    Huang, M.J.5
  • 5
    • 46249096082 scopus 로고    scopus 로고
    • Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis
    • Motoi N, Szoke J, Riely GJ, Seshan VE, Kris MG, et al. (2008) Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis. Am J Surg Pathol 32: 810-827.
    • (2008) Am J Surg Pathol , vol.32 , pp. 810-827
    • Motoi, N.1    Szoke, J.2    Riely, G.J.3    Seshan, V.E.4    Kris, M.G.5
  • 6
    • 58049205542 scopus 로고    scopus 로고
    • Correlation between morphology and EGFR mutations in lung adenocarcinomas Significance of the micropapillary pattern and the hobnail cell type
    • Ninomiya H, Hiramatsu M, Inamura K, Nomura K, Okui M, et al. (2009) Correlation between morphology and EGFR mutations in lung adenocarcinomas Significance of the micropapillary pattern and the hobnail cell type. Lung Cancer 63: 235-240.
    • (2009) Lung Cancer , vol.63 , pp. 235-240
    • Ninomiya, H.1    Hiramatsu, M.2    Inamura, K.3    Nomura, K.4    Okui, M.5
  • 7
    • 84862779691 scopus 로고    scopus 로고
    • High incidence of EGFR mutations in Korean men smokers with no intratumoral heterogeneity of lung adenocarcinomas: correlation with histologic subtypes, EGFR/TTF-1 expressions, and clinical features
    • Sun PL, Seol H, Lee HJ, Yoo SB, Kim H, et al. (2012) High incidence of EGFR mutations in Korean men smokers with no intratumoral heterogeneity of lung adenocarcinomas: correlation with histologic subtypes, EGFR/TTF-1 expressions, and clinical features. J Thorac Oncol 7: 323-330.
    • (2012) J Thorac Oncol , vol.7 , pp. 323-330
    • Sun, P.L.1    Seol, H.2    Lee, H.J.3    Yoo, S.B.4    Kim, H.5
  • 8
    • 84885021725 scopus 로고    scopus 로고
    • KRAS mutations are associated with solid growth pattern and tumor-infiltrating leukocytes in lung adenocarcinoma
    • doi:10.1038/modpathol.2013.74
    • Rekhtman N, Ang DC, Riely GJ, Ladanyi M, Moreira AL (2013) KRAS mutations are associated with solid growth pattern and tumor-infiltrating leukocytes in lung adenocarcinoma. Mod Pathol doi: 10.1038/modpathol.2013.74.
    • (2013) Mod Pathol
    • Rekhtman, N.1    Ang, D.C.2    Riely, G.J.3    Ladanyi, M.4    Moreira, A.L.5
  • 9
    • 34548182258 scopus 로고    scopus 로고
    • Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features
    • Finberg KE, Sequist LV, Joshi VA, Muzikansky A, Miller JM, et al. (2007) Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features. J Mol Diagn 9: 320-326.
    • (2007) J Mol Diagn , vol.9 , pp. 320-326
    • Finberg, K.E.1    Sequist, L.V.2    Joshi, V.A.3    Muzikansky, A.4    Miller, J.M.5
  • 10
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, et al. (2010) Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 363: 1693-1703.
    • (2010) N Engl J Med , vol.363 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3    Shaw, A.T.4    Solomon, B.5
  • 11
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis
    • Shaw AT, Yeap BY, Solomon BJ, Riely GJ, Gainor J, et al. (2011) Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol 12: 1004-1012.
    • (2011) Lancet Oncol , vol.12 , pp. 1004-1012
    • Shaw, A.T.1    Yeap, B.Y.2    Solomon, B.J.3    Riely, G.J.4    Gainor, J.5
  • 12
    • 69349083935 scopus 로고    scopus 로고
    • Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
    • Rodig SJ, Mino-Kenudson M, Dacic S, Yeap BY, Shaw A, et al. (2009) Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 15: 5216-5223.
    • (2009) Clin Cancer Res , vol.15 , pp. 5216-5223
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3    Yeap, B.Y.4    Shaw, A.5
  • 13
    • 63949087355 scopus 로고    scopus 로고
    • EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset
    • Inamura K, Takeuchi K, Togashi Y, Hatano S, Ninomiya H, et al. (2009) EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol 22: 508-515.
    • (2009) Mod Pathol , vol.22 , pp. 508-515
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3    Hatano, S.4    Ninomiya, H.5
  • 14
    • 79955467025 scopus 로고    scopus 로고
    • Frequent ALK rearrangement and TTF-1/p63 co-expression in lung adenocarcinoma with signet-ring cell component
    • Yoshida A, Tsuta K, Watanabe S, Sekine I, Fukayama M, et al. (2011) Frequent ALK rearrangement and TTF-1/p63 co-expression in lung adenocarcinoma with signet-ring cell component. Lung Cancer 72: 309-315.
    • (2011) Lung Cancer , vol.72 , pp. 309-315
    • Yoshida, A.1    Tsuta, K.2    Watanabe, S.3    Sekine, I.4    Fukayama, M.5
  • 15
    • 84856571417 scopus 로고    scopus 로고
    • ALK translocation is associated with ALK immunoreactivity and extensive signet-ring morphology in primary lung adenocarcinoma
    • Popat S, Gonzalez D, Min T, Swansbury J, Dainton M, et al. (2012) ALK translocation is associated with ALK immunoreactivity and extensive signet-ring morphology in primary lung adenocarcinoma. Lung Cancer 75: 300-305.
    • (2012) Lung Cancer , vol.75 , pp. 300-305
    • Popat, S.1    Gonzalez, D.2    Min, T.3    Swansbury, J.4    Dainton, M.5
  • 16
    • 84868459016 scopus 로고    scopus 로고
    • Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas
    • Nishino M, Klepeis VE, Yeap BY, Bergethon K, Morales-Oyarvide V, et al. (2012) Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas. Mod Pathol 25: 1462-1472.
    • (2012) Mod Pathol , vol.25 , pp. 1462-1472
    • Nishino, M.1    Klepeis, V.E.2    Yeap, B.Y.3    Bergethon, K.4    Morales-Oyarvide, V.5
  • 17
    • 79551563284 scopus 로고    scopus 로고
    • International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma
    • Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, et al. (2011) International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 6: 244-285.
    • (2011) J Thorac Oncol , vol.6 , pp. 244-285
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3    Nicholson, A.G.4    Geisinger, K.R.5
  • 19
    • 79961099514 scopus 로고    scopus 로고
    • Comprehensive histologic analysis of ALK-rearranged lung carcinomas
    • Yoshida A, Tsuta K, Nakamura H, Kohno T, Takahashi F, et al. (2011) Comprehensive histologic analysis of ALK-rearranged lung carcinomas. Am J Surg Pathol 35: 1226-1234.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1226-1234
    • Yoshida, A.1    Tsuta, K.2    Nakamura, H.3    Kohno, T.4    Takahashi, F.5
  • 20
    • 79951769488 scopus 로고    scopus 로고
    • Screening of Anaplastic Lymphoma Kinase Rearrangement by Immunohistochemistry in Non-small Cell Lung Cancer: Correlation with Fluorescence In Situ Hybridization
    • Paik JH, Choe G, Kim H, Choe JY, Lee HJ, et al. (2011) Screening of Anaplastic Lymphoma Kinase Rearrangement by Immunohistochemistry in Non-small Cell Lung Cancer: Correlation with Fluorescence In Situ Hybridization. J Thorac Oncol 6: 466-472.
    • (2011) J Thorac Oncol , vol.6 , pp. 466-472
    • Paik, J.H.1    Choe, G.2    Kim, H.3    Choe, J.Y.4    Lee, H.J.5
  • 21
    • 80051784751 scopus 로고    scopus 로고
    • Detection of ALK gene rearrangement in non-small cell lung cancer: a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization with correlation of ALK protein expression
    • Kim H, Yoo SB, Choe JY, Paik JH, Xu X, et al. (2011) Detection of ALK gene rearrangement in non-small cell lung cancer: a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization with correlation of ALK protein expression. J Thorac Oncol 6: 1359-1366.
    • (2011) J Thorac Oncol , vol.6 , pp. 1359-1366
    • Kim, H.1    Yoo, S.B.2    Choe, J.Y.3    Paik, J.H.4    Xu, X.5
  • 22
    • 70349336416 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
    • Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, et al. (2009) Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 27: 4247-4253.
    • (2009) J Clin Oncol , vol.27 , pp. 4247-4253
    • Shaw, A.T.1    Yeap, B.Y.2    Mino-Kenudson, M.3    Digumarthy, S.R.4    Costa, D.B.5
  • 23
    • 74249091138 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutation and pathologic-radiologic correlation between multiple lung nodules with ground-glass opacity differentiates multicentric origin from intrapulmonary spread
    • Chung JH, Choe G, Jheon S, Sung SW, Kim TJ, et al. (2009) Epidermal growth factor receptor mutation and pathologic-radiologic correlation between multiple lung nodules with ground-glass opacity differentiates multicentric origin from intrapulmonary spread. J Thorac Oncol 4: 1490-1495.
    • (2009) J Thorac Oncol , vol.4 , pp. 1490-1495
    • Chung, J.H.1    Choe, G.2    Jheon, S.3    Sung, S.W.4    Kim, T.J.5
  • 24
    • 1542330018 scopus 로고    scopus 로고
    • Combined status of MUC1 mucin and surfactant apoprotein A expression can predict the outcome of patients with small-size lung adenocarcinoma
    • Tsutsumida H, Goto M, Kitajima S, Kubota I, Hirotsu Y, et al. (2004) Combined status of MUC1 mucin and surfactant apoprotein A expression can predict the outcome of patients with small-size lung adenocarcinoma. Histopathology 44: 147-155.
    • (2004) Histopathology , vol.44 , pp. 147-155
    • Tsutsumida, H.1    Goto, M.2    Kitajima, S.3    Kubota, I.4    Hirotsu, Y.5
  • 25
    • 84878225629 scopus 로고    scopus 로고
    • DeltaNp63 (p40) distribution inside lung cancer: a driver biomarker approach to tumor characterization
    • Pelosi G, Rossi G, Cavazza A, Righi L, Maisonneuve P, et al. (2013) DeltaNp63 (p40) distribution inside lung cancer: a driver biomarker approach to tumor characterization. Int J Surg Pathol 21: 229-239.
    • (2013) Int J Surg Pathol , vol.21 , pp. 229-239
    • Pelosi, G.1    Rossi, G.2    Cavazza, A.3    Righi, L.4    Maisonneuve, P.5
  • 26
    • 84874984968 scopus 로고    scopus 로고
    • Alteration of the E-Cadherin/beta-Catenin Complex Is an Independent Poor Prognostic Factor in Lung Adenocarcinoma
    • Kim H, Yoo SB, Sun P, Jin Y, Jheon S, et al. (2013) Alteration of the E-Cadherin/beta-Catenin Complex Is an Independent Poor Prognostic Factor in Lung Adenocarcinoma. Korean J Pathol 47: 44-51.
    • (2013) Korean J Pathol , vol.47 , pp. 44-51
    • Kim, H.1    Yoo, S.B.2    Sun, P.3    Jin, Y.4    Jheon, S.5
  • 27
    • 84857794792 scopus 로고    scopus 로고
    • p40 (DeltaNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma
    • Bishop JA, Teruya-Feldstein J, Westra WH, Pelosi G, Travis WD, et al. (2012) p40 (DeltaNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma. Mod Pathol 25: 405-415.
    • (2012) Mod Pathol , vol.25 , pp. 405-415
    • Bishop, J.A.1    Teruya-Feldstein, J.2    Westra, W.H.3    Pelosi, G.4    Travis, W.D.5
  • 28
    • 80053570615 scopus 로고    scopus 로고
    • Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens
    • Rekhtman N, Ang DC, Sima CS, Travis WD, Moreira AL, (2011) Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens. Mod Pathol 24: 1348-1359.
    • (2011) Mod Pathol , vol.24 , pp. 1348-1359
    • Rekhtman, N.1    Ang, D.C.2    Sima, C.S.3    Travis, W.D.4    Moreira, A.L.5
  • 29
    • 0037308609 scopus 로고    scopus 로고
    • P63 is expressed in basal and myoepithelial cells of human normal and tumor salivary gland tissues
    • Bilal H, Handra-Luca A, Bertrand JC, Fouret PJ, (2003) P63 is expressed in basal and myoepithelial cells of human normal and tumor salivary gland tissues. J Histochem Cytochem 51: 133-139.
    • (2003) J Histochem Cytochem , vol.51 , pp. 133-139
    • Bilal, H.1    Handra-Luca, A.2    Bertrand, J.C.3    Fouret, P.J.4
  • 30
    • 0036741920 scopus 로고    scopus 로고
    • P63 in pulmonary epithelium, pulmonary squamous neoplasms, and other pulmonary tumors
    • Wang BY, Gil J, Kaufman D, Gan L, Kohtz DS, et al. (2002) P63 in pulmonary epithelium, pulmonary squamous neoplasms, and other pulmonary tumors. Hum Pathol 33: 921-926.
    • (2002) Hum Pathol , vol.33 , pp. 921-926
    • Wang, B.Y.1    Gil, J.2    Kaufman, D.3    Gan, L.4    Kohtz, D.S.5
  • 31
    • 0036724213 scopus 로고    scopus 로고
    • p63 immunoreactivity in lung cancer: yet another player in the development of squamous cell carcinomas?
    • Pelosi G, Pasini F, Olsen Stenholm C, Pastorino U, Maisonneuve P, et al. (2002) p63 immunoreactivity in lung cancer: yet another player in the development of squamous cell carcinomas? J Pathol 198: 100-109.
    • (2002) J Pathol , vol.198 , pp. 100-109
    • Pelosi, G.1    Pasini, F.2    Olsen Stenholm, C.3    Pastorino, U.4    Maisonneuve, P.5
  • 32
    • 84861231326 scopus 로고    scopus 로고
    • A study of DeltaNp63 expression in lung non-small cell carcinomas
    • Nonaka D, (2012) A study of DeltaNp63 expression in lung non-small cell carcinomas. Am J Surg Pathol 36: 895-899.
    • (2012) Am J Surg Pathol , vol.36 , pp. 895-899
    • Nonaka, D.1
  • 33
    • 84884685296 scopus 로고    scopus 로고
    • Immunohistochemical Profiling of ALK Fusion Gene-Positive Adenocarcinomas of the Lung
    • DOI:10.1177/1066896913489345
    • Sakai Y, Nakai T, Ohbayashi C, Imagawa N, Yanagita E, et al. (2013) Immunohistochemical Profiling of ALK Fusion Gene-Positive Adenocarcinomas of the Lung. Int J Surg Pathol DOI: 10.1177/1066896913489345.
    • (2013) Int J Surg Pathol
    • Sakai, Y.1    Nakai, T.2    Ohbayashi, C.3    Imagawa, N.4    Yanagita, E.5


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