-
1
-
-
10644241977
-
Pharmacogenetics of the cytochromes P450
-
A.K. Daly Pharmacogenetics of the cytochromes P450 Curr Top Med Chem 4 2004 1733 1744
-
(2004)
Curr Top Med Chem
, vol.4
, pp. 1733-1744
-
-
Daly, A.K.1
-
2
-
-
0036394942
-
Clinical significance of the cytochrome P450 2C19 genetic polymorphism
-
Z. Desta, X. Zhao, J.G. Shin, and D.A. Flockhart Clinical significance of the cytochrome P450 2C19 genetic polymorphism Clin Pharmacokinet 41 2002 913 958
-
(2002)
Clin Pharmacokinet
, vol.41
, pp. 913-958
-
-
Desta, Z.1
Zhao, X.2
Shin, J.G.3
Flockhart, D.A.4
-
3
-
-
79957673659
-
The influence of CYP2C19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of P2Y(12) inhibitors
-
M.J. Price, U.S. Tantry, and P.A. Gurbel The influence of CYP2C19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of P2Y(12) inhibitors Rev Cardiovasc Med 12 2011 1 12
-
(2011)
Rev Cardiovasc Med
, vol.12
, pp. 1-12
-
-
Price, M.J.1
Tantry, U.S.2
Gurbel, P.A.3
-
4
-
-
84855953171
-
PharmGKB summary: Very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19
-
S.A. Scott, K. Sangkuhl, A.R. Shuldiner, J.S. Hulot, C.F. Thorn, R.B. Altman, and T.E. Klein PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19 Pharmacogenet Genomics 22 2012 159 165
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 159-165
-
-
Scott, S.A.1
Sangkuhl, K.2
Shuldiner, A.R.3
Hulot, J.S.4
Thorn, C.F.5
Altman, R.B.6
Klein, T.E.7
-
5
-
-
0029122980
-
A 2.4-megabase physical map spanning the CYP2C gene cluster on chromosome 10q24
-
I.C. Gray, C. Nobile, R. Muresu, S. Ford, and N.K. Spurr A 2.4-megabase physical map spanning the CYP2C gene cluster on chromosome 10q24 Genomics 28 1995 328 332
-
(1995)
Genomics
, vol.28
, pp. 328-332
-
-
Gray, I.C.1
Nobile, C.2
Muresu, R.3
Ford, S.4
Spurr, N.K.5
-
6
-
-
0034792584
-
Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
-
J.A. Goldstein Clinical relevance of genetic polymorphisms in the human CYP2C subfamily Br J Clin Pharmacol 52 2001 349 355
-
(2001)
Br J Clin Pharmacol
, vol.52
, pp. 349-355
-
-
Goldstein, J.A.1
-
7
-
-
85027954420
-
The Human Cytochrome P450 (CYP) Allele Nomenclature website: A peer-reviewed database of CYP variants and their associated effects
-
S.C. Sim, and M. Ingelman-Sundberg The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects Hum Genomics 4 2010 278 281
-
(2010)
Hum Genomics
, vol.4
, pp. 278-281
-
-
Sim, S.C.1
Ingelman-Sundberg, M.2
-
8
-
-
0037131892
-
CYP2C9 allelic variants: Ethnic distribution and functional significance
-
H.G. Xie, H.C. Prasad, R.B. Kim, and C.M. Stein CYP2C9 allelic variants: ethnic distribution and functional significance Adv Drug Deliv Rev 54 2002 1257 1270
-
(2002)
Adv Drug Deliv Rev
, vol.54
, pp. 1257-1270
-
-
Xie, H.G.1
Prasad, H.C.2
Kim, R.B.3
Stein, C.M.4
-
9
-
-
77957295385
-
Worldwide allele frequency distribution of four polymorphisms associated with warfarin dose requirements
-
K.A. Ross, A.W. Bigham, M. Edwards, A. Gozdzik, G. Suarez-Kurtz, and E.J. Parra Worldwide allele frequency distribution of four polymorphisms associated with warfarin dose requirements J Hum Genet 55 2010 582 589
-
(2010)
J Hum Genet
, vol.55
, pp. 582-589
-
-
Ross, K.A.1
Bigham, A.W.2
Edwards, M.3
Gozdzik, A.4
Suarez-Kurtz, G.5
Parra, E.J.6
-
10
-
-
77952927473
-
Combined CYP2C9, VKORC1 and CYP4F2 frequencies among racial and ethnic groups
-
S.A. Scott, R. Khasawneh, I. Peter, R. Kornreich, and R.J. Desnick Combined CYP2C9, VKORC1 and CYP4F2 frequencies among racial and ethnic groups Pharmacogenomics 11 2010 781 791
-
(2010)
Pharmacogenomics
, vol.11
, pp. 781-791
-
-
Scott, S.A.1
Khasawneh, R.2
Peter, I.3
Kornreich, R.4
Desnick, R.J.5
-
11
-
-
78650427535
-
Population-specific documentation of pharmacogenomic markers and their allelic frequencies in FINDbase
-
M. Georgitsi, E. Viennas, V. Gkantouna, E. Christodoulopoulou, Z. Zagoriti, C. Tafrali, F. Ntellos, O. Giannakopoulou, A. Boulakou, P. Vlahopoulou, E. Kyriacou, J. Tsaknakis, A. Tsakalidis, K. Poulas, G. Tzimas, and G.P. Patrinos Population-specific documentation of pharmacogenomic markers and their allelic frequencies in FINDbase Pharmacogenomics 12 2011 49 58
-
(2011)
Pharmacogenomics
, vol.12
, pp. 49-58
-
-
Georgitsi, M.1
Viennas, E.2
Gkantouna, V.3
Christodoulopoulou, E.4
Zagoriti, Z.5
Tafrali, C.6
Ntellos, F.7
Giannakopoulou, O.8
Boulakou, A.9
Vlahopoulou, P.10
Kyriacou, E.11
Tsaknakis, J.12
Tsakalidis, A.13
Poulas, K.14
Tzimas, G.15
Patrinos, G.P.16
-
12
-
-
84881126177
-
Multi-ethnic distribution of clinically relevant CYP2C genotypes and haplotypes
-
S. Martis, I. Peter, J.S. Hulot, R. Kornreich, R.J. Desnick, and S.A. Scott Multi-ethnic distribution of clinically relevant CYP2C genotypes and haplotypes Pharmacogenomics J 13 2013 369 377
-
(2013)
Pharmacogenomics J
, vol.13
, pp. 369-377
-
-
Martis, S.1
Peter, I.2
Hulot, J.S.3
Kornreich, R.4
Desnick, R.J.5
Scott, S.A.6
-
13
-
-
78049326068
-
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
-
J.L. Mega, T. Simon, J.P. Collet, J.L. Anderson, E.M. Antman, K. Bliden, C.P. Cannon, N. Danchin, B. Giusti, P. Gurbel, B.D. Horne, J.S. Hulot, A. Kastrati, G. Montalescot, F.J. Neumann, L. Shen, D. Sibbing, P.G. Steg, D. Trenk, S.D. Wiviott, and M.S. Sabatine Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis JAMA 304 2010 1821 1830
-
(2010)
JAMA
, vol.304
, pp. 1821-1830
-
-
Mega, J.L.1
Simon, T.2
Collet, J.P.3
Anderson, J.L.4
Antman, E.M.5
Bliden, K.6
Cannon, C.P.7
Danchin, N.8
Giusti, B.9
Gurbel, P.10
Horne, B.D.11
Hulot, J.S.12
Kastrati, A.13
Montalescot, G.14
Neumann, F.J.15
Shen, L.16
Sibbing, D.17
Steg, P.G.18
Trenk, D.19
Wiviott, S.D.20
Sabatine, M.S.21
more..
-
14
-
-
77955638355
-
ACCF/AHA clopidogrel clinical alert: Approaches to the FDA "boxed warning": A report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons
-
D.R. Holmes Jr., G.J. Dehmer, S. Kaul, D. Leifer, P.T. O'Gara, and C.M. Stein ACCF/AHA clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons J Am Coll Cardiol 56 2010 321 341
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 321-341
-
-
Holmes, Jr.D.R.1
Dehmer, G.J.2
Kaul, S.3
Leifer, D.4
O'Gara, P.T.5
Stein, C.M.6
-
15
-
-
82955240702
-
CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics, and clinical efficacy in post-myocardial infarction patients
-
J.S. Hulot, J.P. Collet, G. Cayla, J. Silvain, F. Allanic, A. Bellemain-Appaix, S.A. Scott, and G. Montalescot CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics, and clinical efficacy in post-myocardial infarction patients Circ Cardiovasc Interv 4 2011 422 428
-
(2011)
Circ Cardiovasc Interv
, vol.4
, pp. 422-428
-
-
Hulot, J.S.1
Collet, J.P.2
Cayla, G.3
Silvain, J.4
Allanic, F.5
Bellemain-Appaix, A.6
Scott, S.A.7
Montalescot, G.8
-
16
-
-
84859965783
-
Clopidogrel: A case for indication-specific pharmacogenetics
-
J.A. Johnson, D.M. Roden, L.J. Lesko, E. Ashley, T.E. Klein, and A.R. Shuldiner Clopidogrel: a case for indication-specific pharmacogenetics Clin Pharmacol Ther 91 2012 774 776
-
(2012)
Clin Pharmacol Ther
, vol.91
, pp. 774-776
-
-
Johnson, J.A.1
Roden, D.M.2
Lesko, L.J.3
Ashley, E.4
Klein, T.E.5
Shuldiner, A.R.6
-
17
-
-
84860538806
-
Point-of-care genetic testing for personalization of antiplatelet treatment (RAPID GENE): A prospective, randomised, proof-of-concept trial
-
J.D. Roberts, G.A. Wells, M.R. Le May, M. Labinaz, C. Glover, M. Froeschl, A. Dick, J.F. Marquis, E. O'Brien, S. Goncalves, I. Druce, A. Stewart, M.H. Gollob, and D.Y. So Point-of-care genetic testing for personalization of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial Lancet 379 2012 1705 1711
-
(2012)
Lancet
, vol.379
, pp. 1705-1711
-
-
Roberts, J.D.1
Wells, G.A.2
Le May, M.R.3
Labinaz, M.4
Glover, C.5
Froeschl, M.6
Dick, A.7
Marquis, J.F.8
O'Brien, E.9
Goncalves, S.10
Druce, I.11
Stewart, A.12
Gollob, M.H.13
So, D.Y.14
-
18
-
-
84862620703
-
Operational implementation of prospective genotyping for personalized medicine: The design of the Vanderbilt PREDICT project
-
J.M. Pulley, J.C. Denny, J.F. Peterson, G.R. Bernard, C.L. Vnencak-Jones, A.H. Ramirez, J.T. Delaney, E. Bowton, K. Brothers, K. Johnson, D.C. Crawford, J. Schildcrout, D.R. Masys, H.H. Dilks, R.A. Wilke, E.W. Clayton, E. Shultz, M. Laposata, J. McPherson, J.N. Jirjis, and D.M. Roden Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project Clin Pharmacol Ther 92 2012 87 95
-
(2012)
Clin Pharmacol Ther
, vol.92
, pp. 87-95
-
-
Pulley, J.M.1
Denny, J.C.2
Peterson, J.F.3
Bernard, G.R.4
Vnencak-Jones, C.L.5
Ramirez, A.H.6
Delaney, J.T.7
Bowton, E.8
Brothers, K.9
Johnson, K.10
Crawford, D.C.11
Schildcrout, J.12
Masys, D.R.13
Dilks, H.H.14
Wilke, R.A.15
Clayton, E.W.16
Shultz, E.17
Laposata, M.18
McPherson, J.19
Jirjis, J.N.20
Roden, D.M.21
more..
-
19
-
-
84880716424
-
The CLIPMERGE PGx program: Clinical implementation of personalized medicine through electronic health records and genomics-pharmacogenomics
-
O. Gottesman, S.A. Scott, S.B. Ellis, C.L. Overby, A. Ludtke, J.S. Hulot, J. Hall, K. Chatani, K. Myers, J.L. Kannry, and E.P. Bottinger The CLIPMERGE PGx program: clinical implementation of personalized medicine through electronic health records and genomics-pharmacogenomics Clin Pharmacol Ther 94 2013 214 217
-
(2013)
Clin Pharmacol Ther
, vol.94
, pp. 214-217
-
-
Gottesman, O.1
Scott, S.A.2
Ellis, S.B.3
Overby, C.L.4
Ludtke, A.5
Hulot, J.S.6
Hall, J.7
Chatani, K.8
Myers, K.9
Kannry, J.L.10
Bottinger, E.P.11
-
20
-
-
84883170442
-
Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy
-
S.A. Scott, K. Sangkuhl, E.E. Gardner, C.M. Stein, J.S. Hulot, J.L. Mega, D.M. Roden, T.E. Klein, M.S. Sabatine, J.A. Johnson, and A.R. Shuldiner Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy Clin Pharmacol Ther 94 2013 317 323
-
(2013)
Clin Pharmacol Ther
, vol.94
, pp. 317-323
-
-
Scott, S.A.1
Sangkuhl, K.2
Gardner, E.E.3
Stein, C.M.4
Hulot, J.S.5
Mega, J.L.6
Roden, D.M.7
Klein, T.E.8
Sabatine, M.S.9
Johnson, J.A.10
Shuldiner, A.R.11
-
21
-
-
79955463893
-
Pharmacogenetics: From bench to byte-an update of guidelines
-
J.J. Swen, M. Nijenhuis, A. de Boer, L. Grandia, A.H. Maitland-van der Zee, H. Mulder, G.A. Rongen, R.H. van Schaik, T. Schalekamp, D.J. Touw, J. van der Weide, B. Wilffert, V.H. Deneer, and H.J. Guchelaar Pharmacogenetics: from bench to byte-an update of guidelines Clin Pharmacol Ther 89 2011 662 673
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 662-673
-
-
Swen, J.J.1
Nijenhuis, M.2
De Boer, A.3
Grandia, L.4
Maitland-Van Der Zee, A.H.5
Mulder, H.6
Rongen, G.A.7
Van Schaik, R.H.8
Schalekamp, T.9
Touw, D.J.10
Van Der Weide, J.11
Wilffert, B.12
Deneer, V.H.13
Guchelaar, H.J.14
-
22
-
-
84864348920
-
Identification of CYP2C19*4B: Pharmacogenetic implications for drug metabolism including clopidogrel responsiveness
-
S.A. Scott, S. Martis, I. Peter, Y. Kasai, R. Kornreich, and R.J. Desnick Identification of CYP2C19*4B: pharmacogenetic implications for drug metabolism including clopidogrel responsiveness Pharmacogenomics J 12 2012 297 305
-
(2012)
Pharmacogenomics J
, vol.12
, pp. 297-305
-
-
Scott, S.A.1
Martis, S.2
Peter, I.3
Kasai, Y.4
Kornreich, R.5
Desnick, R.J.6
-
23
-
-
84879668006
-
Combined and independent impact of diabetes mellitus and chronic kidney disease on residual platelet reactivity
-
U. Baber, J. Bander, R. Karajgikar, K. Yadav, A. Hadi, K. Theodoropolous, N. Gukathasan, S. Roy, S. Sayeneni, S.A. Scott, J.C. Kovacic, J. Yu, S. Sartori, R. Mehran, J. Uribarri, J. Badimon, P. Muntner, P. Moreno, A.S. Kini, and S.K. Sharma Combined and independent impact of diabetes mellitus and chronic kidney disease on residual platelet reactivity Thromb Haemost 110 2013 118 123
-
(2013)
Thromb Haemost
, vol.110
, pp. 118-123
-
-
Baber, U.1
Bander, J.2
Karajgikar, R.3
Yadav, K.4
Hadi, A.5
Theodoropolous, K.6
Gukathasan, N.7
Roy, S.8
Sayeneni, S.9
Scott, S.A.10
Kovacic, J.C.11
Yu, J.12
Sartori, S.13
Mehran, R.14
Uribarri, J.15
Badimon, J.16
Muntner, P.17
Moreno, P.18
Kini, A.S.19
Sharma, S.K.20
more..
-
24
-
-
70649111382
-
CYP2C9*8 is prevalent among African-Americans: Implications for pharmacogenetic dosing
-
S.A. Scott, M. Jaremko, S.A. Lubitz, R. Kornreich, J.L. Halperin, and R.J. Desnick CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing Pharmacogenomics 10 2009 1243 1255
-
(2009)
Pharmacogenomics
, vol.10
, pp. 1243-1255
-
-
Scott, S.A.1
Jaremko, M.2
Lubitz, S.A.3
Kornreich, R.4
Halperin, J.L.5
Desnick, R.J.6
-
25
-
-
34548103768
-
CYP2C9. CYP2C19 and CYP2D6 allele frequencies in the Ashkenazi Jewish population
-
S.A. Scott, L. Edelmann, R. Kornreich, M. Erazo, and R.J. Desnick CYP2C9. CYP2C19 and CYP2D6 allele frequencies in the Ashkenazi Jewish population Pharmacogenomics 8 2007 721 730
-
(2007)
Pharmacogenomics
, vol.8
, pp. 721-730
-
-
Scott, S.A.1
Edelmann, L.2
Kornreich, R.3
Erazo, M.4
Desnick, R.J.5
-
26
-
-
40749123052
-
Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations
-
S.A. Scott, L. Edelmann, R. Kornreich, and R.J. Desnick Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations Am J Hum Genet 82 2008 495 500
-
(2008)
Am J Hum Genet
, vol.82
, pp. 495-500
-
-
Scott, S.A.1
Edelmann, L.2
Kornreich, R.3
Desnick, R.J.4
-
27
-
-
78049440186
-
Experience with carrier screening and prenatal diagnosis for 16 Ashkenazi Jewish genetic diseases
-
S.A. Scott, L. Edelmann, L. Liu, M. Luo, R.J. Desnick, and R. Kornreich Experience with carrier screening and prenatal diagnosis for 16 Ashkenazi Jewish genetic diseases Hum Mutat 31 2010 1240 1250
-
(2010)
Hum Mutat
, vol.31
, pp. 1240-1250
-
-
Scott, S.A.1
Edelmann, L.2
Liu, L.3
Luo, M.4
Desnick, R.J.5
Kornreich, R.6
-
28
-
-
0025744797
-
Direct haplotype determination by double ARMS: Specificity, sensitivity and genetic applications
-
Y.M. Lo, P. Patel, C.R. Newton, A.F. Markham, K.A. Fleming, and J.S. Wainscoat Direct haplotype determination by double ARMS: specificity, sensitivity and genetic applications Nucleic Acids Res 19 1991 3561 3567
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 3561-3567
-
-
Lo, Y.M.1
Patel, P.2
Newton, C.R.3
Markham, A.F.4
Fleming, K.A.5
Wainscoat, J.S.6
-
29
-
-
36348943475
-
Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
-
J.T. Brandt, S.L. Close, S.J. Iturria, C.D. Payne, N.A. Farid, C.S. Ernest II, D.R. Lachno, D. Salazar, and K.J. Winters Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel J Thromb Haemost 5 2007 2429 2436
-
(2007)
J Thromb Haemost
, vol.5
, pp. 2429-2436
-
-
Brandt, J.T.1
Close, S.L.2
Iturria, S.J.3
Payne, C.D.4
Farid, N.A.5
Ernest, I.I.C.S.6
Lachno, D.R.7
Salazar, D.8
Winters, K.J.9
-
30
-
-
79955116606
-
High doses of clopidogrel to overcome genetic resistance: The randomized crossover CLOVIS-2 (Clopidogrel and Response Variability Investigation Study 2)
-
J.P. Collet, J.S. Hulot, G. Anzaha, A. Pena, T. Chastre, C. Caron, J. Silvain, G. Cayla, A. Bellemain-Appaix, J.B. Vignalou, S. Galier, O. Barthelemy, F. Beygui, V. Gallois, and G. Montalescot High doses of clopidogrel to overcome genetic resistance: the randomized crossover CLOVIS-2 (Clopidogrel and Response Variability Investigation Study 2) JACC Cardiovasc Interv 4 2011 392 402
-
(2011)
JACC Cardiovasc Interv
, vol.4
, pp. 392-402
-
-
Collet, J.P.1
Hulot, J.S.2
Anzaha, G.3
Pena, A.4
Chastre, T.5
Caron, C.6
Silvain, J.7
Cayla, G.8
Bellemain-Appaix, A.9
Vignalou, J.B.10
Galier, S.11
Barthelemy, O.12
Beygui, F.13
Gallois, V.14
Montalescot, G.15
-
31
-
-
33749339075
-
Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
-
J.S. Hulot, A. Bura, E. Villard, M. Azizi, V. Remones, C. Goyenvalle, M. Aiach, P. Lechat, and P. Gaussem Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects Blood 108 2006 2244 2247
-
(2006)
Blood
, vol.108
, pp. 2244-2247
-
-
Hulot, J.S.1
Bura, A.2
Villard, E.3
Azizi, M.4
Remones, V.5
Goyenvalle, C.6
Aiach, M.7
Lechat, P.8
Gaussem, P.9
-
32
-
-
38449103046
-
Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10 + 12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients
-
B. Giusti, A.M. Gori, R. Marcucci, C. Saracini, I. Sestini, R. Paniccia, S. Valente, D. Antoniucci, R. Abbate, and G.F. Gensini Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10 + 12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients Pharmacogenet Genomics 17 2007 1057 1064
-
(2007)
Pharmacogenet Genomics
, vol.17
, pp. 1057-1064
-
-
Giusti, B.1
Gori, A.M.2
Marcucci, R.3
Saracini, C.4
Sestini, I.5
Paniccia, R.6
Valente, S.7
Antoniucci, D.8
Abbate, R.9
Gensini, G.F.10
-
33
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
J.L. Mega, S.L. Close, S.D. Wiviott, L. Shen, R.D. Hockett, J.T. Brandt, J.R. Walker, E.M. Antman, W. Macias, E. Braunwald, and M.S. Sabatine Cytochrome p-450 polymorphisms and response to clopidogrel N Engl J Med 360 2009 354 362
-
(2009)
N Engl J Med
, vol.360
, pp. 354-362
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Hockett, R.D.5
Brandt, J.T.6
Walker, J.R.7
Antman, E.M.8
Macias, W.9
Braunwald, E.10
Sabatine, M.S.11
-
34
-
-
69249219296
-
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
-
A.R. Shuldiner, J.R. O'Connell, K.P. Bliden, A. Gandhi, K. Ryan, R.B. Horenstein, C.M. Damcott, R. Pakyz, U.S. Tantry, Q. Gibson, T.I. Pollin, W. Post, A. Parsa, B.D. Mitchell, N. Faraday, W. Herzog, and P.A. Gurbel Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy JAMA 302 2009 849 857
-
(2009)
JAMA
, vol.302
, pp. 849-857
-
-
Shuldiner, A.R.1
O'Connell, J.R.2
Bliden, K.P.3
Gandhi, A.4
Ryan, K.5
Horenstein, R.B.6
Damcott, C.M.7
Pakyz, R.8
Tantry, U.S.9
Gibson, Q.10
Pollin, T.I.11
Post, W.12
Parsa, A.13
Mitchell, B.D.14
Faraday, N.15
Herzog, W.16
Gurbel, P.A.17
-
35
-
-
58749090547
-
Genetic determinants of response to clopidogrel and cardiovascular events
-
French Registry of Acute STE, Non STEMII
-
T. Simon, C. Verstuyft, M. Mary-Krause, L. Quteineh, E. Drouet, N. Meneveau, P.G. Steg, J. Ferrieres, N. Danchin, L. Becquemont French Registry of Acute STE, Non STEMII Genetic determinants of response to clopidogrel and cardiovascular events N Engl J Med 360 2009 363 375
-
(2009)
N Engl J Med
, vol.360
, pp. 363-375
-
-
Simon, T.1
Verstuyft, C.2
Mary-Krause, M.3
Quteineh, L.4
Drouet, E.5
Meneveau, N.6
Steg, P.G.7
Ferrieres, J.8
Danchin, N.9
Becquemont, L.10
-
36
-
-
58249135635
-
Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
-
J.P. Collet, J.S. Hulot, A. Pena, E. Villard, J.B. Esteve, J. Silvain, L. Payot, D. Brugier, G. Cayla, F. Beygui, G. Bensimon, C. Funck-Brentano, and G. Montalescot Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study Lancet 373 2009 309 317
-
(2009)
Lancet
, vol.373
, pp. 309-317
-
-
Collet, J.P.1
Hulot, J.S.2
Pena, A.3
Villard, E.4
Esteve, J.B.5
Silvain, J.6
Payot, L.7
Brugier, D.8
Cayla, G.9
Beygui, F.10
Bensimon, G.11
Funck-Brentano, C.12
Montalescot, G.13
-
37
-
-
77953896604
-
Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: A systematic meta-analysis
-
J.S. Hulot, J.P. Collet, J. Silvain, A. Pena, A. Bellemain-Appaix, O. Barthelemy, G. Cayla, F. Beygui, and G. Montalescot Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis J Am Coll Cardiol 56 2010 134 143
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 134-143
-
-
Hulot, J.S.1
Collet, J.P.2
Silvain, J.3
Pena, A.4
Bellemain-Appaix, A.5
Barthelemy, O.6
Cayla, G.7
Beygui, F.8
Montalescot, G.9
-
38
-
-
77958105401
-
Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: A pharmacogenetic analysis
-
J.L. Mega, S.L. Close, S.D. Wiviott, L. Shen, J.R. Walker, T. Simon, E.M. Antman, E. Braunwald, and M.S. Sabatine Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis Lancet 376 2010 1312 1319
-
(2010)
Lancet
, vol.376
, pp. 1312-1319
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Walker, J.R.5
Simon, T.6
Antman, E.M.7
Braunwald, E.8
Sabatine, M.S.9
-
39
-
-
30344457586
-
A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
-
S.C. Sim, C. Risinger, M.L. Dahl, E. Aklillu, M. Christensen, L. Bertilsson, and M. Ingelman-Sundberg A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants Clin Pharmacol Ther 79 2006 103 113
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 103-113
-
-
Sim, S.C.1
Risinger, C.2
Dahl, M.L.3
Aklillu, E.4
Christensen, M.5
Bertilsson, L.6
Ingelman-Sundberg, M.7
-
40
-
-
15444340367
-
A new genetic defect in human CYP2C19: Mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin
-
R.J. Ferguson, S.M. De Morais, S. Benhamou, C. Bouchardy, J. Blaisdell, G. Ibeanu, G.R. Wilkinson, T.C. Sarich, J.M. Wright, P. Dayer, and J.A. Goldstein A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin J Pharmacol Exp Ther 284 1998 356 361
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 356-361
-
-
Ferguson, R.J.1
De Morais, S.M.2
Benhamou, S.3
Bouchardy, C.4
Blaisdell, J.5
Ibeanu, G.6
Wilkinson, G.R.7
Sarich, T.C.8
Wright, J.M.9
Dayer, P.10
Goldstein, J.A.11
|