Impaired slow axonal transport in diabetic peripheral nerve is independent of RAGE

European Journal of Neuroscience

Volumn 38, Issue 8, 2013, Pages 3159-3168

  Juranek, Judyta K ^a,b   Geddis, Matthew S ^a,c   Rosario, Rosa ^a,b   Schmidt, Ann Marie ^a,b  

^a NewYork Presbyterian Hospital   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Axonal transport; Diabetes; MDia1; Mice; RAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; BINDING PROTEIN; LIGAND; MAMMALIAN DIAPHANOUS 1; NEUROFILAMENT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DIABETIC NEUROPATHY; DISEASE COURSE; MALE; MOUSE; NERVE FIBER TRANSPORT; NONHUMAN; PATHOPHYSIOLOGY; PERIKARYON; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SCIATIC NERVE INJURY; STREPTOZOCIN DIABETES;

AXONAL TRANSPORT; DIABETES; MDIA1; MICE; RAGE;

ANIMALS; AXONAL TRANSPORT; BINDING SITES; CARRIER PROTEINS; DIABETES MELLITUS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE CRUSH; NEUROFILAMENT PROTEINS; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; SCIATIC NERVE;

EID: 84885961464     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/ejn.12333     Document Type: Article

References (40)

1. Abbate, S.L., Atkinson, M.B. & Breuer, A.C. (1991) Amount and speed of fast axonal transport in diabetes. Diabetes, 40, 111-117.
2. Arakawa, Y., Bito, H., Furuyashiki, T., Tsuji, T., Takemoto-Kimura, S., Kimura, K., Nozaki, K., Hashimoto, N. & Narumiya, S. (2003) Control of axon elongation via an SDF-1α/Rho/mDia pathway in cultured cerebellar granule neurons. J. Cell Biol., 161, 381-391.
3. Bomers, K., Braendgaard, H., Flyvbjerg, A. & Sidenius, P. (1996) Redistribution of axoplasm in the motor root in experimental diabetes. Acta Neuropathol., 92, 98-101.
4. Cullum, N.A., Mahon, J., Stringer, K. & McLean, W.G. (1991) Glycation of rat sciatic nerve tubulin in experimental diabetes mellitus. Diabetologia, 34, 387-389.
5. Dahlin, L.B., Meiri, K.F., McLean, W.G., Rydevik, B. & Sjostrand, J. (1986) Effects of nerve compression on fast axonal transport in streptozotocin-induced diabetes mellitus. An experimental study in the sciatic nerve of rats. Diabetologia, 29, 181-185.
6. Deshpande, A.D., Harris-Hayes, M. & Schootman, M. (2008) Epidemiology of diabetes and diabetes-related complications. Phys. Ther., 88, 1254-1264.
7. Duran-Jimenez, B., Dobler, D., Moffatt, S., Rabbani, N., Streuli, C.H., Thornalley, P.J., Tomlinson, D.R. & Gardiner, N.J. (2009) Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetes. Diabetes, 58, 2893-2903.
8. Fernyhough, P. & Schmidt, R.E. (2002) Neurofilaments in diabetic neuropathy. Int. Rev. Neurobiol., 50, 115-144.
9. Hudson, B.I., Kalea, A.Z., Del Mar Arriero, M., Harja, E., Boulanger, E., D'Agati, V. & Schmidt, A.M. (2008) Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42. J. Biol. Chem., 283, 34457-34468.
10. Juranek, J.K., Aleshin, A., Rattigan, E.M., Johnson, L., Qu, W., Song, F., Ananthakrishnan, R., Quadri, N., Yan, S.D., Ramasamy, R., Schmidt, A.M. & Geddis, M.S. (2010) Morphological changes and immunohistochemical expression of RAGE and its ligands in the sciatic nerve of hyperglycemic pig (Sus scrofa). Biochem. Insights, 2010, 47-59.
11. Juranek, J.K., Geddis, M.S., Song, F., Zhang, J., Garcia, J., Rosario, R., Yan, S.F., Brannagan, T.H. & Schmidt, A.M. (2013) RAGE deficiency improves postinjury sciatic nerve regeneration in type 1 diabetic mice. Diabetes, 62, 931-943.
12. Larsen, J.R. & Sidenius, P. (1989) Slow axonal transport of structural polypeptides in rat, early changes in streptozocin diabetes, and effect of insulin treatment. J. Neurochem., 52, 390-401.
13. Li, J.Y., Jahn, R., Hou, X.E., Kling-Petersen, A. & Dahlström, A. (1996a) Distribution of Rab3a in rat nervous system: comparison with other synaptic vesicle proteins and neuropeptides. Brain Res., 706, 103-112.
14. Li, J.Y., Edelmann, L., Jahn, R. & Dahlstrom, A. (1996b) Axonal transport and distribution of synaptobrevin I and II in the rat peripheral nervous system. J. Neurosci., 16, 137-147.
15. Macioce, P., Filliatreau, G., Figliomeni, B., Hassig, R., Thiery, J. & Di Giamberardino, L. (1989) Slow axonal transport impairment of cytoskeletal proteins in streptozocin-induced diabetic neuropathy. J. Neurochem., 53, 1261-1267.
16. Mao, Y. (2011) FORMIN a link between kinetochores and microtubule ends. Trends Cell Biol., 21, 625-629.
17. McLean, W.G. (1997) The role of axonal cytoskeleton in diabetic neuropathy. Neurochem. Res., 22, 951-956.
18. McLean, W.G., Pekiner, C., Cullum, N.A. & Casson, I.F. (1992) Posttranslational modifications of nerve cytoskeletal proteins in experimental diabetes. Mol. Neurobiol., 6, 225-237.
19. Medori, R., Autilio-Gambetti, L., Monaco, S. & Gambetti, P. (1985) Experimental diabetic neuropathy: impairment of slow transport with changes in axon cross-sectional area. Proc. Natl. Acad. Sci. USA, 82, 7716-7720.
20. Medori, R., Autilio-Gambetti, L., Jenich, H. & Gambetti, P. (1988a) Changes in axon size and slow axonal transport are related in experimental diabetic neuropathy. Neurology, 38, 597-601.
21. Medori, R., Jenich, H., Autilio-Gambetti, L. & Gambetti, P. (1988b) Experimental diabetic neuropathy: similar changes of slow axonal transport and axonal size in different animal models. J. Neurosci., 8, 1814-1821.
22. Miller, C.C., Ackerley, S., Brownlees, J., Grierson, A.J., Jacobsen, N.J. & Thornhill, P. (2002) Axonal transport of neurofilaments in normal and disease states. Cell. Mol. Life Sci., 59, 323-330.
23. Origlia, N., Righi, M., Capsoni, S., Cattaneo, A., Fang, F., Stern, D.M., Chen, J.X., Schmidt, A.M., Arancio, O., Yan, S.D. & Domenici, L. (2008) Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction. J. Neurosci., 28, 3521-3530.
24. Pekiner, C. & McLean, W.G. (1991) Neurofilament protein phosphorylation in spinal cord of experimentally diabetic rats. J. Neurochem., 56, 1362-1367.
25. Pekiner, C., Cullum, N.A., Hughes, J.N., Hargreaves, A.J., Mahon, J., Casson, I.F. & McLean, W.G. (1993) Glycation of brain actin in experimental diabetes. J. Neurochem., 61, 436-442.
26. Rai, V., Maldonado, A.Y., Burz, D.S., Reverdatto, S., Yan, S.F., Schmidt, A.M. & Shekhtman, A. (2012) Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1. J. Biol. Chem., 287, 5133-5144.
27. Ramasamy, R., Vannucci, S.J., Yan, S.S., Herold, K., Yan, S.F. & Schmidt, A.M. (2005) Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation. Glycobiology, 15, 16R-28R.
28. Reiniger, N., Lau, K., McCalla, D., Eby, B., Cheng, B., Lu, Y., Qu, W., Quadri, N., Ananthakrishnan, R., Furmansky, M., Rosario, R., Song, F., Rai, V., Weinberg, A., Friedman, R., Ramasamy, R., D'Agati, V. & Schmidt, A.M. (2010) Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse. Diabetes, 59, 2043-2054.
29. Rong, L.L., Yan, S.F., Wendt, T., Hans, D., Pachydaki, S., Bucciarelli, L.G., Adebayo, A., Qu, W., Lu, Y., Kostov, K., Lalla, E., Yan, S.D., Gooch, C., Szabolcs, M., Trojaborg, W., Hays, A.P. & Schmidt, A.M. (2004) RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways. Faseb J., 18, 1818-1825.
30. Sakaguchi, T., Yan, S.F., Yan, S.D., Belov, D., Rong, L.L., Sousa, M., Andrassy, M., Marso, S.P., Duda, S., Arnold, B., Liliensiek, B., Nawroth, P.P., Stern, D.M., Schmidt, A.M. & Naka, Y. (2003) Central role of RAGE-dependent neointimal expansion in arterial restenosis. J. Clin. Invest., 111, 959-972.
31. Shinohara, R., Thumkeo, D., Kamijo, H., Kaneko, N., Sawamoto, K., Watanabe, K., Takebayashi, H., Kiyonari, H., Ishizaki, T., Furuyashiki, T. & Narumiya, S. (2012) A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors. Nat. Neurosci., 15, 373-380, S1-S2.
32. Smith, A.G. & Singleton, J.R. (2012) Diabetic neuropathy. Continuum (Minneap. Minn.), 18, 60-84.
33. Sugimoto, K., Yasujima, M. & Yagihashi, S. (2008) Role of advanced glycation end products in diabetic neuropathy. Curr. Pharm. Design, 14, 953-961.
34. Thumkeo, D., Shinohara, R., Watanabe, K., Takebayashi, H., Toyoda, Y., Tohyama, K., Ishizaki, T., Furuyashiki, T. & Narumiya, S. (2011) Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia. PLoS ONE, 6, e25465.
35. Tomlinson, D.R., Filliatreau, G., Figliomeni, B., Hassig, R., Di Giamberardino, L. & Willars, G.B. (1990) Proteins of slow axonal transport in sciatic motoneurones of rats with streptozotocin-induced diabetes or galactosaemia. Diabetes Res. Clin. Pr., 9, 15-21.
36. Toure, F., Fritz, G., Li, Q., Rai, V., Daffu, G., Zou, Y.S., Rosario, R., Ramasamy, R., Alberts, A.S., Yan, S.F. & Schmidt, A.M. (2012) Formin mDia1 mediates vascular remodeling via integration of oxidative and signal transduction pathways. Circ. Res., 110, 1279-1293.
37. Vitadello, M., Filliatreau, G., Dupont, J.L., Hassig, R., Gorio, A. & Di Giamberardino, L. (1985) Altered axonal transport of cytoskeletal proteins in the mutant diabetic mouse. J. Neurochem., 45, 860-868.
38. Wang, Z.Y., Li, J.Y., Danscher, G. & Dahlstrom, A. (2002) Localization of zinc-enriched neurons in the mouse peripheral sympathetic system. Brain Res., 928, 165-174.
39. Watanabe, N. & Higashida, C. (2004) Formins: processive cappers of growing actin filaments. Exp. Cell Res., 301, 16-22.
40. Xu, Y., Toure, F., Qu, W., Lin, L., Song, F., Shen, X., Rosario, R., Garcia, J., Schmidt, A.M. & Yan, S.F. (2010) Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. J. Biol. Chem., 285, 23233-23240.