The isolectin IB4 binds RET receptor tyrosine kinase in microglia

Journal of Neurochemistry

Volumn 126, Issue 4, 2013, Pages 428-436

  Boscia, Francesca ^a   Esposito, Carla Lucia ^b   Casamassa, Antonella ^a   De Franciscis, Vittorio ^b   Annunziato, Lucio ^a   Cerchia, Laura ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CNR   (Italy)

Author keywords

brain ischemia; GDNF; IB4; microglia; Ret receptor

Indexed keywords

CELL MARKER; ISOLECTIN B4; PROTEIN RET; GFRA1 PROTEIN, RAT; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; GRIFFONIA SIMPLICIFOLIA LECTINS; PLANT LECTIN;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN FUNCTION; BRAIN ISCHEMIA; CELL STRAIN 3T3; CELL SURFACE; CONTROLLED STUDY; FIBROBLAST; GENETIC TRANSFECTION; GRIFFONIA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; MALE; MICROGLIA; MICROGLIAL CELL CULTURE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RAT; TISSUE SECTION; ANIMAL; BRAIN CORTEX; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; IB4; METABOLISM; NEUROFIBROMATOSIS; NEWBORN; PATHOLOGY; PHYSIOLOGY; PRIMARY CELL CULTURE; RET RECEPTOR; SIGNAL TRANSDUCTION; SIPPLE SYNDROME; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

GRIFFONIA SIMPLICIFOLIA; RATTUS;

BRAIN ISCHEMIA; GDNF; IB4; MICROGLIA; RET RECEPTOR;

ANIMALS; ANIMALS, NEWBORN; BRAIN ISCHEMIA; CELL LINE, TUMOR; CEREBRAL CORTEX; FLUORESCENT ANTIBODY TECHNIQUE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; MALE; MICE; MICROGLIA; MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A; MULTIPLE ENDOCRINE NEOPLASIA TYPE 2B; NIH 3T3 CELLS; PLANT LECTINS; PRIMARY CELL CULTURE; PROTO-ONCOGENE PROTEINS C-RET; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84885960368     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12209     Document Type: Article

References (44)

1. Airaksinen M. S., and, Saarma M., (2002) The GDNF family: signalling, biological functions and therapeutic value. Nat. Rev. Neurosci. 3, 383-394.
2. Alroy J., Goyal V., and, Skutelsky E., (1987) Lectin histochemistry of mammalian endothelium. Histochemistry 86, 603-607.
3. Arenas E., Trupp M., Akerud P., and, Ibáñez C. F., (1995) GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron 15, 1465-1473.
4. Balding P., and, Gold E. R., (1975) Observations on the reaction of en(a-)cells with sophora japonica haemagglutinin. Z. Immunitatsforsch. Exp. Klin. Immunol. 145, 156-165.
5. Barondes S. H., (1988) Bifunctional properties of lectins: lectins redefined. Trends Biochem. Sci. 13, 480-482.
6. Bennett D. L., Michael G. J., Ramachandran N., Munson J. B., Averill S., Yan Q., McMahon S. B., and, Priestley J. V., (1998) A distinct subgroup of small DRG cells express GDNF receptor components and GDNF is protective for these neurons after nerve injury. J. Neurosci. 18, 3059-3072.
7. Boscia F., Ferraguti F., Moroni F., Annunziato L., and, Pellegrini-Giampietro D. E., (2008) mGlu1α and CB1 receptors are co-expressed in a subset of interneurons in the CA1 region of organotypic hippocampal slice cultures and adult rat brain. Neuropharmacology 55, 428-439.
8. Boscia F., Esposito C. L., Di Crisci A., de Franciscis V., Annunziato L., and, Cerchia L., (2009a) GDNF selectively induces microglial activation and neuronal survival in CA1/CA3 hippocampal regions exposed to NMDA insult through Ret/ERK signalling. PLoS ONE 4, e6486.
9. Boscia F., Gala R., Pannaccione A., Secondo A., Scorziello A., Di Renzo G., and, Annunziato L., (2009b) NCX1 expression and functional activity increase in microglia invading the infarct core. Stroke 40, 3608-3617.
10. Boscia F., D'Avanzo C., Pannaccione A., Secondo A., Casamassa A., Formisano L., Guida N., and, Annunziato L., (2012) Silencing or knocking out the Na(+)/Ca(2+) exchanger-3 (NCX3) impairs oligodendrocyte differentiation. Cell Death Differ. 19, 562-572.
11. Brabec R. K., Peters B. P., Bernstein I. A., Gray R. H., and, Goldstein I. J., (1980) Differential lectin binding to cellular membranes in the epidermis of the newborn rat. Proc. Natl Acad. Sci. USA 77, 477-479.
12. Buj-Bello A., Buchman V. L., Horton A., Rosenthal A., and, Davies A. M., (1995) GDNF is an age-specific survival factor for sensory and autonomic neurons. Neuron 15, 821-828.
13. Cerchia L., and, de Franciscis V., (2006) MEN2A and MEN2B syndromes: a unique gene for two diseases, in Trends in Cellular Signaling (, Dave E., Caplin Nova Science Publishers ed.), pp. 79-109. Nova Publishers Inc, New York, USA.
14. Cerchia L., Libri D., Carlomagno M. S., and, de Franciscis V., (2003) The soluble ectodomain of RetC634Y inhibits both the wild-type and the constitutively active Ret. Biochem. J. 372, 897-903.
15. Cerchia L., Duconge′ F., Pestourie C., Boulay J., Aissouni Y., Gombert K., Tavitian B., de Franciscis V., and, Libri D., (2005) Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase. PLoS Biol. 3, e123.
16. Chang Y. P., Fang K. M., Lee T. I., and, Tzeng S. F., (2006) Regulation of microglial activities by glial cell line derived neurotrophic factor. J. Cell. Biochem. 97, 501-511.
17. Colton C. A., Abel C., Patchett J., Keri J., and, Yao J., (1992) Lectin staining of cultured CNS microglia. J. Histochem. Cytochem. 40, 505-512.
18. Colucci-D'Amato G. L., D'Alessio A., Filliatreau G., Florio T., Di Giamberardino L., Chiappetta G., Vecchio G., Fusco A., Santoro M., and, de Franciscis V., (1996) Presence of physiologically stimulated RET in adult rat brain: induction of RET expression during nerve regeneration. Cell Growth Differ. 7, 1081-1086.
19. Esposito C. L., D'Alessio A., de Franciscis V., and, Cerchia L., (2008) A cross-talk between TrkB and Ret tyrosine kinases receptors mediates neuroblastoma cells differentiation. PLoS ONE 3 (2), e1643.
20. Esposito F., Boscia F., Franco R., Tornincasa M., Fusco A., Kitazawa S., Looijenga L. H., and, Chieffi P., (2011) Down-regulation of oestrogen receptor-β associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas. J. Pathol. 224, 110-120.
21. Franz S., Frey B., Sheriff A., Gaipl U. S., Beer A., Voll R. E., Kalden J. R., and, Herrmann M., (2006) Lectins detect changes of the glycosylation status of plasma membrane constituents during late apoptosis. Cytometry A 69, 230-239.
22. Goldstein I. J., and, Winter H. G., (1999) The Griffonia simplicifolia I-B4 isolectin. A probe for alpha-D-galactosyl end groups. Subcell. Biochem. 32, 127-141.
23. Henderson C. E., Phillips H. S., Pollock R. A., et al,. (1994) GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science 266, 1062-1106.
24. Honda S., Nakajima K., Nakamura Y., Imai Y., and, Kohsaka S., (1999) Rat primary cultured microglia express glial cell line-derived neurotrophic factor receptors. Neurosci. Lett. 275, 203-206.
25. Kawai K., Ishizu H., and, Kuroda S., (2001) Lectin cytochemistry of rat cerebral and cerebellar neuronal cells. Neuropathology 21, 13-18.
26. Kjaer S., and, Ibáñez C. F., (2003) Intrinsic susceptibility to misfolding of a hot-spot for Hirschsprung disease mutations in the ectodomain of RET. Hum. Mol. Genet. 12, 2133-2144.
27. Leclere P., Ekström P., Edström A., Priestley J., Averill S., and, Tonge D. A., (1998) Effects of glial cell line-derived neurotrophic factor on axonal growth and apoptosis in adult mammalian sensory neurons in vitro. Neuroscience 82, 545-558.
28. Lin L. F., Doherty D. H., Lile J. D., Bektesh S., and, Collins F., (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130-1132.
29. Lunemann A., Ullrich A., Diestel A., Jons T., Ninnemann O., Kovac A., Pohl E. E., Hass R., Nitsch R., and, Hendrix S., (2006) Macrophage/microglia activation factor expression is restricted to lesion-associated microglial cells after brain trauma. Glia 53, 412-419.
30. Miyazaki H., Nagashima K., Okuma Y., and, Nomura Y., (2002) Expression of Ret receptor tyrosine kinase after transient forebrain ischemia is modulated by glial cell line-derived neurotrophic factor in rat hippocampus. Neurosci. Lett. 318, 1-4.
31. Molliver D. C., Wright D. E., Leitner M. L., Parsadanian A. S., Doster K., Wen D., Yan Q., and, Snider W. D., (1997) IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life. Neuron 19, 849-861.
32. Mount H. T., Dean D. O., Alberch J., Dreyfus C. F., and, Black I. B., (1995) Glial cell linederived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proc. Natl Acad. Sci. USA 92, 9092-9096.
33. Pearse D. D., Pereira F. C., Stolyarova A., Barakat D. J., and, Bunge M. B., (2004) Inhibition of tumor necrosis factor- α by antisense targeting produces immunophenotypical and morphological changes in injury- activated microglia and macrophages. Eur. J. Neurosci. 20, 3387-3396.
34. Rémy S., Naveilhan P., Brachet P., and, Neveu I., (2001) Differential regulation of GDNF, neurturin, and their receptors in primary cultures of rat glial cells. J. Neurosci. Res. 64, 242-251.
35. Runeberg-Roos P., and, Saarma M., (2007) Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases. Ann. Med. 39, 572-580.
36. Saijo K., and, Glass C. K., (2011) Microglial cell origin and phenotypes in health and disease. Nat. Rev. Immunol. 11, 775-787.
37. Santoro M., Carlomagno F., Romano A., et al,. (1995) Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B. Science 267, 381-383.
38. Sariola H., and, Saarma M., (2003) Novel functions and signalling pathways for GDNF. J. Cell Sci. 116, 3855-3862.
39. Streit W. J., (1990) An improved staining method for rat microglial cells using the lectin from Griffonia simplicifolia (GSA I-B4). J. Histochem. Cytochem. 38, 1683-1686.
40. Thacker M., Zhang F. L., Jungnickel S. R., and, Furness J. B., (2006) Binding of isolectin IB4 to neurons of the mouse enteric nervous system. J. Mol. Histol. 37, 61-68.
41. Trupp M., Arenas E., Fainzilber M., Nilsson A. S., Sieber B. A., Grigoriou M., Kilkenny C., Salazar-Grueso E., Pachnis V., and, Arumäe U., (1996) Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381, 785-788.
42. Wang Y., Lin S. Z., Chiou A. L., Williams L. R., and, Hoffer B. J., (1997) Glial cell line derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex. J. Neurosci. 17, 4341-4348.
43. Wang R., Guo W., Ossipov M. H., Vanderah T. W., Porreca F., and, Lai J., (2003) Glial cell line-derived neurotrophic factor normalizes neurochemical changes in injured dorsal root ganglion neurons and prevents the expression of experimental neuropathic pain. Neuroscience 121, 815-824.
44. Williams L. R., Inouye G., Cummins V., and, Pelleymounter M. A., (1996) Glial cell line derived neurotrophic factor sustains axotomized basal forebrain cholinergic neurons in vivo: dose- response comparison to nerve growth factor and brain derived neurotrophic factor. J. Pharmacol. Exp. Ther. 277, 1140-1151.