Identification of molecular determinants for a potent mammalian TRPA1 antagonist by utilizing species differences

Journal of Molecular Neuroscience

Volumn 51, Issue 3, 2013, Pages 754-762

  Nakatsuka, Kazumasa ^a   Gupta, Rupai ^b   Saito, Shigeru ^b   Banzawa, Nagako ^a   Takahashi, Kenji ^a   Tominaga, Makoto ^b   Ohta, Toshio ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

A967079; AP18; Cinnamaldehyde; Intracellular calcium; Membrane current; Mutagenesis; Species difference; TRPA1; Xenopus oocyte

Indexed keywords

AMINO ACID; ANALGESIC AGENT; TRANSIENT RECEPTOR POTENTIAL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG;

ARTICLE; EMBRYO; HUMAN; HUMAN CELL; MAMMAL; MEMBRANE CURRENT; MUTAGENESIS; MUTANT; NONHUMAN; PAIN RECEPTOR; SPECIES DIFFERENCE; XENOPUS TROPICALIS;

MAMMALIA; XENOPUS TROPICALIS;

ANALGESICS, NON-NARCOTIC; ANIMALS; BINDING SITES; CALCIUM CHANNELS; HEK293 CELLS; HUMANS; MUTATION; NERVE TISSUE PROTEINS; OXIMES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SPECIES SPECIFICITY; TRANSIENT RECEPTOR POTENTIAL CHANNELS; XENOPUS;

EID: 84885958800     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0060-2     Document Type: Article

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