Abnormally upregulated αb-crystallin was highly coincidental with the astrogliosis in the brains of scrapie-infected hamsters and human patients with prion diseases

Journal of Molecular Neuroscience

Volumn 51, Issue 3, 2013, Pages 734-748

  Wang, Ke ^a,b   Zhang, Jin ^b,c   Xu, Yin ^b   Ren, Ke ^b   Xie, Wu Ling ^a,b   Yan, Yu E ^b   Zhang, Bao Yun ^b   Shi, Qi ^b   Liu, Yong ^a   Dong, Xiao Ping ^b,d  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c Shandong Entry Exit Inspection and Quarantine Bureau   (China)

^d INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

B crystallin; Astrogliosis; GFAP; Prion disease; PrP

Indexed keywords

BETA CRYSTALLIN; CRYSTALLIN; GLIAL FIBRILLARY ACIDIC PROTEIN; PRION PROTEIN ANTIBODY; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN TISSUE; CELL CULTURE; CELL LYSATE; CHEMOLUMINESCENCE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORPUS CALLOSUM; CREUTZFELDT JAKOB DISEASE; DISEASE SEVERITY; ESCHERICHIA COLI; FLUORESCENT TREPONEMA ANTIBODY TEST; GENETIC ASSOCIATION; HAMSTER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INCUBATION TIME; INSOMNIA; MOLECULAR INTERACTION; NEUROPATHOLOGY; NONHUMAN; PARIETAL LOBE; PROTEIN PURIFICATION; SCRAPIE; SIGNAL TRANSDUCTION; THALAMUS; UPREGULATION; WESTERN BLOTTING;

CRICETINAE; ESCHERICHIA COLI;

ALPHA-CRYSTALLIN B CHAIN; ANIMALS; ASTROCYTES; BRAIN; CRICETINAE; CRICETULUS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; HEK293 CELLS; HUMANS; NEURONS; ORGAN SPECIFICITY; PRION DISEASES; PRPSC PROTEINS; UP-REGULATION;

EID: 84885957759     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0057-x     Document Type: Article

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