Quantification of cardiac sympathetic nerve density with N- 11C-guanyl-meta-octopamine and tracer kinetic analysis

Journal of Nuclear Medicine

Volumn 54, Issue 9, 2013, Pages 1645-1652

  Raffel, David M ^a   Koeppe, Robert A ^a   Jung, Yong Woon ^a   Gu, Guie ^a   Jang, Keun Sam ^a   Sherman, Phillip S ^a   Quesada, Carole A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Hydroxyephedrine; Metaiodobenzylguanidine; Norepinephrine transporter; Positron emission tomography

Indexed keywords

CARBON META HYDROXYEPHEDRINE C 11; CARBON METAIODOBENZYLGUANIDINE; DESIPRAMINE; DIAGNOSTIC AGENT; N CARBON GUANYL META OCTOPAMINE C 11; NORADRENALIN TRANSPORTER; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; (3 IODOBENZYL)GUANIDINE; CARBON; DRUG DERIVATIVE; GUANINE; N GUANYL M OCTOPAMINE; N-GUANYL-M-OCTOPAMINE; OCTOPAMINE;

ANIMAL EXPERIMENT; ARTICLE; COMPARTMENT MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; DRUG STRUCTURE; DRUG UPTAKE; FEMALE; HEART NERVE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RHESUS MONKEY; SYMPATHETIC NERVE; ADRENERGIC SYSTEM; ANIMAL; BIOLOGICAL MODEL; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SIMULATION; DOSE RESPONSE; HEART; HYDROXYEPHEDRINE; INNERVATION; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; RAT; REPRODUCIBILITY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY;

HYDROXYEPHEDRINE; METAIODOBENZYLGUANIDINE; NOREPINEPHRINE TRANSPORTER; POSITRON EMISSION TOMOGRAPHY;

ANIMALS; CARBON RADIOISOTOPES; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANINE; HEART; IMAGE INTERPRETATION, COMPUTER-ASSISTED; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; OCTOPAMINE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SYMPATHETIC NERVOUS SYSTEM;

EID: 84885920277     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.113.120659     Document Type: Article

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