Thymol antifungal mode of action involves telomerase inhibition

Medical Mycology

Volumn 51, Issue 8, 2013, Pages 826-834

  Darvishi, Emad ^a,b   Omidi, Mansoor ^a   Bushehri, Ali Akbar ^a   Golshani, Ashkan ^b   Smith, Myron L ^b  

^a UNIVERSITY OF TEHRAN   (Iran)

^b CARLETON UNIVERSITY   (Canada)

Author keywords

Antifungal molecular mechanism; Chemical genetic profile analysis; Reverse transcriptase subunit of telomerase; Telomere length maintenance; Thymol antifungal mode of action; galactosidase expression assay

Indexed keywords

CYCLOHEXIMIDE; EST2 PROTEIN; GENOMIC DNA; HOLOENZYME; MESSENGER RNA; MRE11 PROTEIN; PROTEIN; PROTEIN CWH8; PROTEIN KEM1; PROTEIN SRB5; PROTEIN SRB8; PROTEIN SSN3; PROTEIN SUR4; RIBONUCLEOPROTEIN; RNA; RNA DIRECTED DNA POLYMERASE; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; THYMOL; THYMOQUINONE; TLC1 PROTEIN; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; APOPTOSIS; ARTICLE; CELL AGING; CONTROLLED STUDY; DELETION MUTANT; DRUG MECHANISM; ENZYME INHIBITION; GENE DELETION; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; RESTRICTION FRAGMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; SACCHAROMYCES CEREVISIAE; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE RESTRICTION FRAGMENT; TELOMERE SHORTENING; TRANSCRIPTION TERMINATION; YEAST CELL;

SACCHAROMYCES CEREVISIAE;

ANTIFUNGAL AGENTS; CULTURE MEDIA; GENE DELETION; GENE EXPRESSION PROFILING; MICROBIAL SENSITIVITY TESTS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TELOMERASE; THYMOL;

EID: 84885904608     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.3109/13693786.2013.795664     Document Type: Article

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