Cellular Resolution Functional Imaging in Behaving Rats Using Voluntary Head Restraint

Neuron

Volumn 80, Issue 2, 2013, Pages 371-384

  Scott, Benjamin B ^a   Brody, Carlos D ^a   Tank, David W ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CELLULAR RESOLUTION FUNCTIONAL IMAGING; CONTROLLED STUDY; FLUORESCENCE; IMAGING; IN VIVO STUDY; INSTRUMENTAL CONDITIONING; MALE; MICROSCOPE; NEUROLOGICAL AND SENSORIAL PROCEDURES; NEUROPIL; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY STIMULATION; VOLUNTARY HEAD RESTRAINT;

ANIMALS; CONDITIONING, OPERANT; EVOKED POTENTIALS, VISUAL; FUNCTIONAL NEUROIMAGING; HEAD; IMMOBILIZATION; MALE; MOLECULAR IMAGING; RATS; VISUAL CORTEX;

EID: 84885872180     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2013.08.002     Document Type: Article

References (43)

1. Aitman T.J., Critser J.K., Cuppen E., Dominiczak A., Fernandez-Suarez X.M., Flint J., Gauguier D., Geurts A.M., Gould M., Harris P.C., et al. Progress and prospects in rat genetics: a community view. Nat. Genet. 2008, 40:516-522.
2. Akerboom J., Chen T.W., Wardill T.J., Tian L., Marvin J.S., Mutlu S., Calderón N.C., Esposti F., Borghuis B.G., Sun X.R., et al. Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci. 2012, 32:13819-13840.
3. Borsook D., Becerra L., Hargreaves R. A role for fMRI in optimizing CNS drug development. Nat. Rev. Drug Discov. 2006, 5:411-424.
4. Brunton B.W., Botvinick M.M., Brody C.D. Rats and humans can optimally accumulate evidence for decision-making. Science 2013, 340:95-98.
5. Chen T.W., Wardill T.J., Sun Y., Pulver S.R., Renninger S.L., Baohan A., Schreiter E.R., Kerr R.A., Orger M.B., Jayaraman V., et al. Ultrasensitive fluorescent proteins for imaging neuronal activity. Nature 2013, 499:295-300.
6. Denk W., Strickler J.H., Webb W.W. Two-photon laser scanning fluorescence microscopy. Science 1990, 248:73-76.
7. Dolgin E. The knockout rat pack. Nat. Med. 2010, 16:254-257.
8. Dombeck D.A., Khabbaz A.N., Collman F., Adelman T.L., Tank D.W. Imaging large-scale neural activity with cellular resolution in awake, mobile mice. Neuron 2007, 56:43-57.
9. Dombeck D.A., Harvey C.D., Tian L., Looger L.L., Tank D.W. Functional imaging of hippocampal place cells at cellular resolution during virtual navigation. Nat. Neurosci. 2010, 13:1433-1440.
10. Dwinell M.R. Online tools for understanding rat physiology. Brief. Bioinform. 2010, 11:431-439.
11. Erlich J.C., Bialek M., Brody C.D. A cortical substrate for memory-guided orienting in the rat. Neuron 2011, 72:330-343.
12. Geurts A.M., Cost G.J., Freyvert Y., Zeitler B., Miller J.C., Choi V.M., Jenkins S.S., Wood A., Cui X., Meng X., et al. Knockout rats via embryo microinjection of zinc-finger nucleases. Science 2009, 325:433.
13. Girman S.V. Means of restricting movements of conscious rats during neurophysiological experiments. Zh. Vyssh. Nerv. Deiat. Im. I. P. Pavlova 1980, 30:1087-1089.
14. Girman S.V. Responses of neurons of primary visual cortex of awake unrestrained rats to visual stimuli. Neurosci. Behav. Physiol. 1985, 15:379-386.
15. Girman S.V., Sauvé Y., Lund R.D. Receptive field properties of single neurons in rat primary visual cortex. J.Neurophysiol. 1999, 82:301-311.
16. Harvey M.A., Bermejo R., Zeigler H.P. Discriminative whisking in the head-fixed rat: optoelectronic monitoring during tactile detection and discrimination tasks. Somatosens. Mot. Res. 2001, 18:211-222.
17. Harvey C.D., Collman F., Dombeck D.A., Tank D.W. Intracellular dynamics of hippocampal place cells during virtual navigation. Nature 2009, 461:941-946.
18. Harvey C.D., Coen P., Tank D.W. Choice-specific sequencesinparietal cortex during a virtual-navigation decision task. Nature 2012, 484:62-68.
19. Helmchen F., Fee M.S., Tank D.W., Denk W. A miniature head-mounted two-photon microscope. high-resolution brain imaging in freely moving animals. Neuron 2001, 31:903-912.
20. Hölscher C., Schnee A., Dahmen H., Setia L., Mallot H.A. Rats are able to navigate in virtual environments. J.Exp. Biol. 2005, 208:561-569.
21. Houweling A.R., Brecht M. Behavioural report of single neuron stimulation in somatosensory cortex. Nature 2008, 451:65-68.
22. Huang G., Tong C., Kumbhani D.S., Ashton C., Yan H., Ying Q.-L. Beyond knockout rats: new insights into finer genome manipulation in rats. Cell Cycle 2011, 10:1059-1066.
23. Huber D., Gutnisky D.A., Peron S., O'Connor D.H., Wiegert J.S., Tian L., Oertner T.G., Looger L.L., Svoboda K. Multiple dynamic representations in the motor cortex during sensorimotor learning. Nature 2012, 484:473-478.
24. Kerr J.N.D., Nimmerjahn A. Functional imaging in freely moving animals. Curr. Opin. Neurobiol. 2012, 22:45-53.
25. Kornblum H.I., Araujo D.M., Annala A.J., Tatsukawa K.J., Phelps M.E., Cherry S.R. in vivo imaging of neuronal activation and plasticity in the rat brain by high resolution positron emission tomography (microPET). Nat. Biotechnol. 2000, 18:655-660.
26. Macé E., Montaldo G., Cohen I., Baulac M., Fink M., Tanter M. Functional ultrasound imaging of the brain. Nat. Methods 2011, 8:662-664.
27. Miesenböck G. Optogenetic control of cells and circuits. Annu. Rev. Cell Dev. Biol. 2011, 27:731-758.
28. Miri A., Daie K., Burdine R.D., Aksay E., Tank D.W. Regression-based identification of behavior-encoding neurons during large-scale opticalimaging of neural activity at cellular resolution. J.Neurophysiol. 2011, 105:964-980.
29. Ohki K., Chung S., Ch'ng Y.H., Kara P., Reid R.C. Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex. Nature 2005, 433:597-603.
30. Parnavelas J.G., Burne R.A., Lin C.-S. Receptive field properties of neurons in the visual cortex of the rat. Neurosci. Lett. 1981, 27:291-296.
31. Piyawattanametha W., Cocker E.D., Burns L.D., Barretto R.P.J., Jung J.C., Ra H., Solgaard O., Schnitzer M.J. in vivo brain imaging using a portable 2.9g two-photon microscope based on a microelectromechanical systems scanning mirror. Opt. Lett. 2009, 34:2309-2311.
32. Pologruto T.A., Sabatini B.L., Svoboda K. ScanImage: flexiblesoftware for operating laser scanning microscopes. Biomed. Eng. Online 2003, 2:13.
33. Rickgauer J.P., Tank D.W. Two-photon excitation of channelrhodopsin-2 at saturation. Proc. Natl. Acad. Sci. USA 2009, 106:15025-15030.
34. Sawinski J., Wallace D.J., Greenberg D.S., Grossmann S., Denk W., Kerr J.N.D. Visually evoked activity in cortical cells imaged in freely moving animals. Proc. Natl. Acad. Sci. USA 2009, 106:19557-19562.
35. Schwarz C., Hentschke H., Butovas S., Haiss F., Stüttgen M.C., Gerdjikov T.V., Bergner C.G., Waiblinger C. The head-fixed behaving rat-procedures and pitfalls. Somatosens. Mot. Res. 2010, 27:131-148.
36. Stüttgen M.C., Rüter J., Schwarz C. Two psychophysical channels of whisker deflection in rats align with two neuronal classes of primary afferents. J.Neurosci. 2006, 26:7933-7941.
37. Tesson L., Usal C., Ménoret S., Leung E., Niles B.J., Remy S., Santiago Y., Vincent A.I., Meng X., Zhang L., et al. Knockout rats generated by embryo microinjection of TALENs. Nat. Biotechnol. 2011, 29:695-696.
38. Tian L., Hires S.A., Mao T., Huber D., Chiappe M.E., Chalasani S.H., Petreanu L., Akerboom J., McKinney S.A., Schreiter E.R., et al. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nat. Methods 2009, 6:875-881.
39. Uchida N., Mainen Z.F. Speed and accuracy of olfactory discrimination in the rat. Nat. Neurosci. 2003, 6:1224-1229.
40. Verhagen J.V., Wesson D.W., Netoff T.I., White J.A., Wachowiak M. Sniffing controls an adaptive filter of sensory input to the olfactory bulb. Nat. Neurosci. 2007, 10:631-639.
41. Winter Y., Schaefers A.T.U. A sorting system with automated gates permits individual operant experiments with mice from a social home cage. J.Neurosci. Methods 2011, 196:276-280.
42. Witten I.B., Steinberg E.E., Lee S.Y., Davidson T.J., Zalocusky K.A., Brodsky M., Yizhar O., Cho S.L., Gong S., Ramakrishnan C., et al. Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron 2011, 72:721-733.
43. Zhang F., Wang L.-P., Brauner M., Liewald J.F., Kay K., Watzke N., Wood P.G., Bamberg E., Nagel G., Gottschalk A., Deisseroth K. Multimodal fast optical interrogation of neural circuitry. Nature 2007, 446:633-639.