메뉴 건너뛰기




Volumn 37, Issue 11, 2013, Pages 1246-1258

Enhanced chondrogenesis through specific growth factors in a buffalo embryonic stem cell model

Author keywords

Bone morphogenetic proteins 2; Buffalo; Chondrogenesis; Embryonic stem cells; Fibroblast growth factor 10; Transforming growth factor beta1

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 2; FIBROBLAST GROWTH FACTOR 10; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84885863159     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1002/cbin.10153     Document Type: Article
Times cited : (2)

References (55)
  • 2
    • 80051779230 scopus 로고    scopus 로고
    • Enhanced chondrogenic marker expression of human mesenchymal stem cells by interaction with both TGF-beta3 and hyaluronic acid
    • Bhang SH, Jeon JY, La WG, Seong JY, Hwang JW, Ryu SE, Kim BS (2011) Enhanced chondrogenic marker expression of human mesenchymal stem cells by interaction with both TGF-beta3 and hyaluronic acid. Biotechnol Appl Biochem 58:271-6.
    • (2011) Biotechnol Appl Biochem , vol.58 , pp. 271-276
    • Bhang, S.H.1    Jeon, J.Y.2    La, W.G.3    Seong, J.Y.4    Hwang, J.W.5    Ryu, S.E.6    Kim, B.S.7
  • 3
    • 0027977006 scopus 로고
    • Transrepression of type II collagen by TGF-beta and FGF is protein kinase C dependent and is mediated through regulatory sequences in the promoter and first intron
    • Bradham DM, in der Wiesche B, Precht P, Balakir R, Horton W (1994) Transrepression of type II collagen by TGF-beta and FGF is protein kinase C dependent and is mediated through regulatory sequences in the promoter and first intron. J Cell Physiol 158:61-8.
    • (1994) J Cell Physiol , vol.158 , pp. 61-68
    • Bradham, D.M.1    in der Wiesche, B.2    Precht, P.3    Balakir, R.4    Horton, W.5
  • 4
    • 0021358883 scopus 로고
    • Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
    • Bradley A, Evans M, Kaufman MH, Robertson E (1984) Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309:255-6.
    • (1984) Nature , vol.309 , pp. 255-256
    • Bradley, A.1    Evans, M.2    Kaufman, M.H.3    Robertson, E.4
  • 5
    • 0030030944 scopus 로고    scopus 로고
    • Myf-5 and myoD genes are activated in distinct mesenchymal stem cells and determine different skeletal muscle cell lineages
    • Braun T, Arnold HH (1996) Myf-5 and myoD genes are activated in distinct mesenchymal stem cells and determine different skeletal muscle cell lineages. Embo J 15:310-8.
    • (1996) Embo J , vol.15 , pp. 310-318
    • Braun, T.1    Arnold, H.H.2
  • 6
    • 0032735947 scopus 로고    scopus 로고
    • Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis
    • Brown D, Wagner D, Li X, Richardson JA, Olson EN (1999) Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis. Development 126:4317-29.
    • (1999) Development , vol.126 , pp. 4317-4329
    • Brown, D.1    Wagner, D.2    Li, X.3    Richardson, J.A.4    Olson, E.N.5
  • 8
    • 8744240235 scopus 로고    scopus 로고
    • Substantiation of the use of L-carnitine for the treatment of alcoholism
    • Bykov IL, Belkovets AV (2004) [Substantiation of the use of L-carnitine for the treatment of alcoholism]. Eksp Klin Farmakol 67:51-5.
    • (2004) Eksp Klin Farmakol , vol.67 , pp. 51-55
    • Bykov, I.L.1    Belkovets, A.V.2
  • 12
    • 0035574614 scopus 로고    scopus 로고
    • Regulatory mechanisms in the pathways of cartilage and bone formation
    • de Crombrugghe B, Lefebvre V, Nakashima K (2001) Regulatory mechanisms in the pathways of cartilage and bone formation. Curr Opin Cell Biol 13:721-7.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 721-727
    • de Crombrugghe, B.1    Lefebvre, V.2    Nakashima, K.3
  • 13
    • 0029100688 scopus 로고
    • Formation of cartilage-like spheroids by micromass cultures of murine C3H10T1/2 cells upon treatment with transforming growth factor-beta 1
    • Denker AE, Nicoll SB, Tuan RS (1995) Formation of cartilage-like spheroids by micromass cultures of murine C3H10T1/2 cells upon treatment with transforming growth factor-beta 1. Differentiation 59:25-34.
    • (1995) Differentiation , vol.59 , pp. 25-34
    • Denker, A.E.1    Nicoll, S.B.2    Tuan, R.S.3
  • 15
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature 292:154-6.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 16
    • 0027952883 scopus 로고
    • Induction of chondrogenesis: requirement for synergistic interaction of basic fibroblast growth factor and transforming growth factor-beta
    • Frenz DA, Liu W, Williams JD, Hatcher V, Galinovic-Schwartz V, Flanders KC, Van de Water TR (1994) Induction of chondrogenesis: requirement for synergistic interaction of basic fibroblast growth factor and transforming growth factor-beta. Development 120:415-24.
    • (1994) Development , vol.120 , pp. 415-424
    • Frenz, D.A.1    Liu, W.2    Williams, J.D.3    Hatcher, V.4    Galinovic-Schwartz, V.5    Flanders, K.C.6    Van de Water, T.R.7
  • 17
    • 0029831470 scopus 로고    scopus 로고
    • Role of TGF beta s and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod
    • Ganan Y, Macias D, Duterque-Coquillaud M, Ros MA, Hurle JM (1996) Role of TGF beta s and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod. Development 122:2349-57.
    • (1996) Development , vol.122 , pp. 2349-2357
    • Ganan, Y.1    Macias, D.2    Duterque-Coquillaud, M.3    Ros, M.A.4    Hurle, J.M.5
  • 18
    • 11344286520 scopus 로고    scopus 로고
    • Embryonic stem cells in vitro -prospects for cell and developmental biology, embryotoxicology and cell therapy
    • Guan K, Schmidt MM, Ding Q, Chang H, Wobus AM (1999) Embryonic stem cells in vitro -prospects for cell and developmental biology, embryotoxicology and cell therapy. Altex 16:135-41.
    • (1999) Altex , vol.16 , pp. 135-141
    • Guan, K.1    Schmidt, M.M.2    Ding, Q.3    Chang, H.4    Wobus, A.M.5
  • 19
    • 24744456615 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 (TGFbeta1) regulates ATDC5 chondrogenic differentiation and fibronectin isoform expression
    • Han F, Adams CS, Tao Z, Williams CJ, Zaka R, Tuan RS, Norton PA, Hickok NJ (2005) Transforming growth factor-beta1 (TGFbeta1) regulates ATDC5 chondrogenic differentiation and fibronectin isoform expression. J Cell Biochem 95:750-62.
    • (2005) J Cell Biochem , vol.95 , pp. 750-762
    • Han, F.1    Adams, C.S.2    Tao, Z.3    Williams, C.J.4    Zaka, R.5    Tuan, R.S.6    Norton, P.A.7    Hickok, N.J.8
  • 20
    • 0029947439 scopus 로고    scopus 로고
    • Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro
    • Helgason CD, Sauvageau G, Lawrence HJ, Largman C, Humphries RK (1996) Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro. Blood 87:2740-9.
    • (1996) Blood , vol.87 , pp. 2740-2749
    • Helgason, C.D.1    Sauvageau, G.2    Lawrence, H.J.3    Largman, C.4    Humphries, R.K.5
  • 21
    • 62549085191 scopus 로고    scopus 로고
    • Fibrochondrogenesis of hESCs:growth factor combinations and cocultures
    • Hoben GM, Willard VP, Athanasiou KA (2009) Fibrochondrogenesis of hESCs:growth factor combinations and cocultures. Stem Cells Dev 18:283-92.
    • (2009) Stem Cells Dev , vol.18 , pp. 283-292
    • Hoben, G.M.1    Willard, V.P.2    Athanasiou, K.A.3
  • 23
    • 0024592992 scopus 로고
    • Stimulation of cartilage-matrix proteoglycan synthesis by morphologically transformed chondrocytes grown in the presence of fibroblast growth factor and transforming growth factor-beta
    • Inoue H, Kato Y, Iwamoto M, Hiraki Y, Sakuda M, Suzuki F (1989) Stimulation of cartilage-matrix proteoglycan synthesis by morphologically transformed chondrocytes grown in the presence of fibroblast growth factor and transforming growth factor-beta. J Cell Physiol 138:329-37.
    • (1989) J Cell Physiol , vol.138 , pp. 329-337
    • Inoue, H.1    Kato, Y.2    Iwamoto, M.3    Hiraki, Y.4    Sakuda, M.5    Suzuki, F.6
  • 24
    • 0021931033 scopus 로고
    • Sulfated proteoglycan synthesis by confluent cultures of rabbit costal chondrocytes grown in the presence of fibroblast growth factor
    • Kato Y, Gospodarowicz D (1985) Sulfated proteoglycan synthesis by confluent cultures of rabbit costal chondrocytes grown in the presence of fibroblast growth factor. J Cell Biol 100:477-85.
    • (1985) J Cell Biol , vol.100 , pp. 477-485
    • Kato, Y.1    Gospodarowicz, D.2
  • 26
    • 0034176844 scopus 로고    scopus 로고
    • Embryonic stem cell-derived chondrogenic differentiation in vitro:activation by BMP-2 and BMP-4
    • Kramer J, Hegert C, Guan K, Wobus AM, Muller PK, Rohwedel J (2000) Embryonic stem cell-derived chondrogenic differentiation in vitro:activation by BMP-2 and BMP-4. Mech Dev 92: 193-205.
    • (2000) Mech Dev , vol.92 , pp. 193-205
    • Kramer, J.1    Hegert, C.2    Guan, K.3    Wobus, A.M.4    Muller, P.K.5    Rohwedel, J.6
  • 27
    • 79952202612 scopus 로고    scopus 로고
    • Improved media compositions for the differentiation of embryonic stem cells into osteoblasts and chondrocytes
    • Kuske B, Savkovic V, zur Nieden NI (2011) Improved media compositions for the differentiation of embryonic stem cells into osteoblasts and chondrocytes.MethodsMol Biol 690:195-215.
    • (2011) MethodsMol Biol , vol.690 , pp. 195-215
    • Kuske, B.1    Savkovic, V.2    zur Nieden, N.I.3
  • 28
    • 79957657744 scopus 로고    scopus 로고
    • BMP2 promotes chondrocyte proliferation via the Wnt/ beta-catenin signaling pathway
    • Li X, Peng J, Wu M, Ye H, Zheng C, Wu G, Xu H, Chen X, Liu X (2011) BMP2 promotes chondrocyte proliferation via the Wnt/ beta-catenin signaling pathway. Mol Med Report 4:621-6.
    • (2011) Mol Med Report , vol.4 , pp. 621-626
    • Li, X.1    Peng, J.2    Wu, M.3    Ye, H.4    Zheng, C.5    Wu, G.6    Xu, H.7    Chen, X.8    Liu, X.9
  • 29
    • 0032804051 scopus 로고    scopus 로고
    • Effect of bone morphogenetic protein-12 gene transfer on mesenchymal progenitor cells
    • Lou J, Tu Y, Ludwig FJ, Zhang J, Manske PR (1999a) Effect of bone morphogenetic protein-12 gene transfer on mesenchymal progenitor cells. Clin Orthop Relat Res 333-9.
    • (1999) Clin Orthop Relat Res , pp. 333-339
    • Lou, J.1    Tu, Y.2    Ludwig, F.J.3    Zhang, J.4    Manske, P.R.5
  • 30
    • 0032973123 scopus 로고    scopus 로고
    • Gene therapy: adenovirus-mediated human bone morphogenetic protein-2 gene transfer induces mesenchymal progenitor cell proliferation and differentiation in vitro and bone formation in vivo
    • Lou J, Xu F, Merkel K, Manske P (1999b) Gene therapy: adenovirus-mediated human bone morphogenetic protein-2 gene transfer induces mesenchymal progenitor cell proliferation and differentiation in vitro and bone formation in vivo. J Orthop Res 17:43-50.
    • (1999) J Orthop Res , vol.17 , pp. 43-50
    • Lou, J.1    Xu, F.2    Merkel, K.3    Manske, P.4
  • 31
    • 7944230297 scopus 로고    scopus 로고
    • Roles of FGF-10 on the development of diathrodial limb joints
    • Lovinescu I, Koyama E, Pacifici M (2003) Roles of FGF-10 on the development of diathrodial limb joints. Penn Dent J (Phila) 103(5):9.
    • (2003) Penn Dent J (Phila) , vol.103 , Issue.5 , pp. 9
    • Lovinescu, I.1    Koyama, E.2    Pacifici, M.3
  • 32
    • 0028283476 scopus 로고
    • Recombinant bone morphogenetic protein-4, transforming growth factorbeta 1, and activin A enhance the cartilage phenotype of articular chondrocytes in vitro
    • Luyten FP, Chen P, Paralkar V, Reddi AH (1994) Recombinant bone morphogenetic protein-4, transforming growth factorbeta 1, and activin A enhance the cartilage phenotype of articular chondrocytes in vitro. Exp Cell Res 210:224-9.
    • (1994) Exp Cell Res , vol.210 , pp. 224-229
    • Luyten, F.P.1    Chen, P.2    Paralkar, V.3    Reddi, A.H.4
  • 34
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 78:7634-8.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 35
    • 0033517123 scopus 로고    scopus 로고
    • STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
    • Matsuda T, Nakamura T, Nakao K, Arai T, Katsuki M, Heike T, Yokota T (1999) STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. Embo J 18:4261-9.
    • (1999) Embo J , vol.18 , pp. 4261-4269
    • Matsuda, T.1    Nakamura, T.2    Nakao, K.3    Arai, T.4    Katsuki, M.5    Heike, T.6    Yokota, T.7
  • 36
    • 0026541206 scopus 로고
    • Chronic atropine administration up-regulates rat cortical muscarinic m1 receptor mRNA molecules:assessment with the RT/PCR
    • McKinney M, RobbinsM(1992) Chronic atropine administration up-regulates rat cortical muscarinic m1 receptor mRNA molecules:assessment with the RT/PCR. Brain Res Mol Brain Res 12:39-45.
    • (1992) Brain Res Mol Brain Res , vol.12 , pp. 39-45
    • McKinney, M.1    Robbins, M.2
  • 37
    • 0025949448 scopus 로고
    • Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing
    • Metsaranta M, Toman D, de Crombrugghe B, Vuorio E (1991) Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing. J Biol Chem 266: 16862-9.
    • (1991) J Biol Chem , vol.266 , pp. 16862-9
    • Metsaranta, M.1    Toman, D.2    de Crombrugghe, B.3    Vuorio, E.4
  • 39
    • 77950800100 scopus 로고    scopus 로고
    • Totipotency, pluripotency and nuclear reprogramming
    • Mitalipov S, Wolf D (2009) Totipotency, pluripotency and nuclear reprogramming. Adv Biochem Eng Biotechnol 114:185-99.
    • (2009) Adv Biochem Eng Biotechnol , vol.114 , pp. 185-199
    • Mitalipov, S.1    Wolf, D.2
  • 40
    • 80053177092 scopus 로고    scopus 로고
    • Chondrogenic differentiation of adult mesenchymal stem cells and embryonic cells in collagen scaffolds
    • Ng KK, Thatte HS, Spector M (2011) Chondrogenic differentiation of adult mesenchymal stem cells and embryonic cells in collagen scaffolds. J Biomed Mater Res A 99:275-82.
    • (2011) J Biomed Mater Res A , vol.99 , pp. 275-282
    • Ng, K.K.1    Thatte, H.S.2    Spector, M.3
  • 41
    • 1942504254 scopus 로고    scopus 로고
    • Growth factor regulation of human growth plate chondrocyte proliferation in vitro
    • Olney RC, Wang J, Sylvester JE, Mougey EB (2004) Growth factor regulation of human growth plate chondrocyte proliferation in vitro. Biochem Biophys Res Commun 317:1171-82.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 1171-1182
    • Olney, R.C.1    Wang, J.2    Sylvester, J.E.3    Mougey, E.B.4
  • 42
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts:somatic differentiation in vitro
    • Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A (2000) Embryonic stem cell lines from human blastocysts:somatic differentiation in vitro. Nat Biotechnol 18:399-404.
    • (2000) Nat Biotechnol , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 43
    • 0028179081 scopus 로고
    • Transforming growth factor-beta and bone morphogenetic protein-2 act by distinct mechanisms to promote chick limb cartilage differentiation in vitro
    • Roark EF, Greer K (1994) Transforming growth factor-beta and bone morphogenetic protein-2 act by distinct mechanisms to promote chick limb cartilage differentiation in vitro. Dev Dyn 200:103-16.
    • (1994) Dev Dyn , vol.200 , pp. 103-116
    • Roark, E.F.1    Greer, K.2
  • 44
    • 0032529848 scopus 로고    scopus 로고
    • Loss of beta1 integrin function results in a retardation of myogenic, but an acceleration of neuronal, differentiation of embryonic stem cells in vitro
    • Rohwedel J, Guan K, Zuschratter W, Jin S, Ahnert-Hilger G, Furst D, Fassler R, Wobus AM (1998) Loss of beta1 integrin function results in a retardation of myogenic, but an acceleration of neuronal, differentiation of embryonic stem cells in vitro. Dev Biol 201:167-84.
    • (1998) Dev Biol , vol.201 , pp. 167-184
    • Rohwedel, J.1    Guan, K.2    Zuschratter, W.3    Jin, S.4    Ahnert-Hilger, G.5    Furst, D.6    Fassler, R.7    Wobus, A.M.8
  • 45
    • 0029128423 scopus 로고
    • M-twist expression inhibits mouse embryonic stem cell-derived myogenic differentiation in vitro
    • Rohwedel J,HorakV,HebrokM, Fuchtbauer EM,Wobus AM(1995) M-twist expression inhibits mouse embryonic stem cell-derived myogenic differentiation in vitro. Exp Cell Res 220:92-100.
    • (1995) Exp Cell Res , vol.220 , pp. 92-100
    • Rohwedel, J.1    Horak, V.2    Hebrok, M.3    Fuchtbauer, E.M.4    Wobus, A.M.5
  • 47
    • 0036510743 scopus 로고    scopus 로고
    • Regulation of osteoblast, chondrocyte, and osteoclast functions by fibroblast growth factor (FGF)-18 in comparisonwith FGF-2 and FGF-10
    • Shimoaka T, Ogasawara T, Yonamine A, Chikazu D, Kawano H, Nakamura K, Itoh N, Kawaguchi H (2002) Regulation of osteoblast, chondrocyte, and osteoclast functions by fibroblast growth factor (FGF)-18 in comparisonwith FGF-2 and FGF-10. J Biol Chem 277:7493-500.
    • (2002) J Biol Chem , vol.277 , pp. 7493-7500
    • Shimoaka, T.1    Ogasawara, T.2    Yonamine, A.3    Chikazu, D.4    Kawano, H.5    Nakamura, K.6    Itoh, N.7    Kawaguchi, H.8
  • 49
    • 4444276765 scopus 로고    scopus 로고
    • STAT3 is dispensable for maintenance of self-renewal in nonhuman primate embryonic stem cells
    • Sumi T, Fujimoto Y, Nakatsuji N, Suemori H (2004) STAT3 is dispensable for maintenance of self-renewal in nonhuman primate embryonic stem cells. Stem Cells 22:861-72.
    • (2004) Stem Cells , vol.22 , pp. 861-872
    • Sumi, T.1    Fujimoto, Y.2    Nakatsuji, N.3    Suemori, H.4
  • 50
    • 75649105754 scopus 로고    scopus 로고
    • In vitro derivation of chondrogenic cells from human embryonic stem cells
    • Toh WS, Lee EH, Richards M, Cao T (2010) In vitro derivation of chondrogenic cells from human embryonic stem cells.Methods Mol Biol 584:317-31.
    • (2010) Methods Mol Biol , vol.584 , pp. 317-331
    • Toh, W.S.1    Lee, E.H.2    Richards, M.3    Cao, T.4
  • 51
    • 0017723046 scopus 로고
    • Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture
    • von der Mark K, Gauss V, von der Mark H, Muller P (1977) Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture.Nature 267:531-2.
    • (1977) Nature , vol.267 , pp. 531-532
    • von der Mark, K.1    Gauss, V.2    von der Mark, H.3    Muller, P.4
  • 52
    • 0026721147 scopus 로고
    • The bone morphogenetic protein family and osteogenesis
    • Wozney JM (1992) The bone morphogenetic protein family and osteogenesis. Mol Reprod Dev 32:160-7.
    • (1992) Mol Reprod Dev , vol.32 , pp. 160-167
    • Wozney, J.M.1
  • 53
    • 80052562270 scopus 로고    scopus 로고
    • Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation
    • Xie X, Qin J, Lin SH, Tsai SY, Tsai MJ (2011) Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation. Proc Natl Acad Sci USA 108: 14843-8.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 14843-8
    • Xie, X.1    Qin, J.2    Lin, S.H.3    Tsai, S.Y.4    Tsai, M.J.5
  • 54
    • 14644429806 scopus 로고    scopus 로고
    • Induction of chondro-, osteo-and adipogenesis in embryonic stem cells by bone morphogenetic protein-2:effect of cofactors on differentiating lineages
    • zur Nieden NI, Kempka G, Rancourt DE, Ahr HJ (2005a) Induction of chondro-, osteo-and adipogenesis in embryonic stem cells by bone morphogenetic protein-2:effect of cofactors on differentiating lineages. BMC Dev Biol 5:1.
    • (2005) BMC Dev Biol , vol.5 , pp. 1
    • zur Nieden, N.I.1    Kempka, G.2    Rancourt, D.E.3    Ahr, H.J.4
  • 55
    • 14644429806 scopus 로고    scopus 로고
    • Induction of chondro-, osteo-and adipogenesis in embryonic stem cells by bone morphogenetic protein-2:effect of cofactors on differentiating lineages
    • zur Nieden NI, Kempka G, Rancourt DE, Ahr HJ (2005b) Induction of chondro-, osteo-and adipogenesis in embryonic stem cells by bone morphogenetic protein-2:effect of cofactors on differentiating lineages. BMC Dev Biol 5:1.
    • (2005) BMC Dev Biol , vol.5 , pp. 1
    • zur Nieden, N.I.1    Kempka, G.2    Rancourt, D.E.3    Ahr, H.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.