LOX-1 deletion and macrophage trafficking in atherosclerosis

Biochemical and Biophysical Research Communications

Volumn 440, Issue 2, 2013, Pages 210-214

  Ding, Zufeng ^a   Mizeracki, Adam Milton ^a   Hu, Changping ^a   Mehta, Jawahar L ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Atherosclerosis; LOX 1; Macrophages

Indexed keywords

CHLORDANE; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1;

ADVENTITIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; ATHEROSCLEROSIS; CELL MIGRATION; CHOLESTEROL DIET; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ATHEROSCLEROSIS; LOX-1; MACROPHAGES;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; AORTA; ATHEROSCLEROSIS; CELL MOVEMENT; MACROPHAGES; MICE; MICE, KNOCKOUT; RECEPTORS, LDL; SCAVENGER RECEPTORS, CLASS E;

MUS;

EID: 84885858011     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.09.020     Document Type: Article

References (26)

1. Yang Z., Hall A.G. The financial burden of overweight and obesity among elderly americans: the dynamics of weight, longevity, and health care cost. Health Serv. Res. 2008, 43:849-868.
2. Hansson G.K. Concise review: inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 2005, 352:1685-1695.
3. Mehta J.L., Chen J., Hermonat P.L., et al. Oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders. Cardiovasc. Res. 2006, 69:36-45.
4. Ding Z., Liu S., Wang X., et al. Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis. Sci. Rep. 2013, 3:1077.
5. Li L., Sawamura T., Renier G. Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation. Circ. Res. 2004, 94:892-901.
6. Mehta J.L., Sanada N., Hu C.P., et al. Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ. Res. 2007, 100:1634-1642.
7. Conway J.P., Kinter M. Proteomic and transcriptomic analyses of macrophages with an increased resistance to oxidized low density lipoprotein (oxLDL)-induced cytotoxicity generated by chronic exposure to oxLDL. Mol. Cell. Proteomics 2005, 4:1522-1540.
8. Di Gregorio G.B., Yao-Borengasser A., Rasouli N., et al. Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone. Diabetes 2005, 54:2305-2313.
9. Sacks H.S., Fain J.N. Concise review: human epicardial adipose tissue: a review. Am. Heart J. 2007, 153:907-917.
10. Lohmann C., Schäfer N., Von Lukowicz T., et al. Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets. Atherosclerosis 2009, 207:360-367.
11. Galkina E., Kadl A., Sanders J., et al. Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially l-selectin dependent. J. Exp. Med. 2006, 203:1273-1282.
12. Bruun J.M., Helge J.W., Richelsen B., et al. Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects. Am. J. Physiol. Endocrinol. Metab. 2006, 290:E961-E967.
13. Gordon S., Keshav S., Chung L.P. Mononuclear phagocytes: tissue distribution and functional heterogeneity. Curr. Opin. Immunol. 1988, 1:26-35.
14. Roberts W., Kim C., Zhen L., et al. Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. Immunity 1999, 10:183-196.
15. Carstanjen D., Yamauchi A., Koornneef A., et al. Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways. J. Immunol. 2005, 174:4613-4620.
16. Libby P. Inflammation in atherosclerosis. Nature 2002, 420:868-874.
17. Itabe H., Takano T. Oxidized low density lipoprotein: the occurrence and metabolism in circulation and in foam cells. J. Atheroscler. Thromb. 2000, 7:123-131.
18. Ding Z., Wang X., Schnackenberg L., et al. Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7g. Int. J. Cardiol. 2013, (Epub ahead of print).
19. Honjo M., Nakamura K., Yamashiro K., et al. Lectin-like oxidized LDL receptor-1 is a cell-adhesion molecule involved in endotoxin-induced inflammation. Proc. Natl. Acad. Sci. USA 2003, 100:1274-1279.
20. Nakashima Y., Fujii H., Sumiyoshi S., et al. Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration. Arterioscler. Thromb. Vasc. Biol. 2007, 27:1159-1165.
21. Moreno P.R., Purushothaman K.R., Sirol M., et al. Concise review: neovascularization in human atherosclerosis. Circulation 2006, 113:2245-2252.
22. Vela D., Buja L.M., Madjid M., et al. The role of periadventitial fat in atherosclerosis. Arch. Pathol. Lab. Med. 2007, 131:481-487.
23. Moos M.P., John N., Gräbner R., et al. The lamina adventitia is the major site of immune cell accumulation in standard chow-fed apolipoprotein e-deficient mice. Arterioscler. Thromb. Vasc. Biol. 2005, 25:2386-2391.
24. Coleman R., Hayek T., Keidar S., et al. A mouse model for human atherosclerosis: long-term histopathological study of lesion development in the aortic arch of apolipoprotein E-deficient (E0) mice. Acta Histochem. 2006, 108:415-424.
25. Rekhter M.D., Hicks G.W., Brammer D.W., et al. Hypercholesterolemia causes mechanical weakening of rabbit atheroma: local collagen loss as a prerequisite of plaque rupture. Circ. Res. 2000, 86:101-108.
26. Adiguzel E., Ahmad P.J., Franco C., et al. Collagens in the progression and complications of atherosclerosis. Vasc. Med. 2009, 14:73-89.