In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

NeuroImage

Volumn 84, Issue , 2014, Pages 733-741

  Tsujikawa, Tetsuya ^a   Zoghbi, Sami S ^a   Hong, Jinsoo ^a   Donohue, Sean R ^a   Jenko, Kimberly J ^a   Gladding, Robert L ^a   Halldin, Christer ^b   Pike, Victor W ^a   Innis, Robert B ^a   Fujita, Masahiro ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Cannabinoid; PET; Receptor imaging

Indexed keywords

3 (4 CHLOROPHENYL) N [(4 CYANOPHENYL)SULFONYL] 4 PHENYL 4,5 DIHDYRO 1H PYRAZOLE 1 CARBOXAMIDINE C 11; CANNABINOID 1 RECEPTOR; FMPEP D2 F 18; MEPPEP C 11; MK 9470 F 18; OMAR C 11; TRACER; UNCLASSIFIED DRUG;

ACCURACY; ADULT; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CAUDATE NUCLEUS; CEREBELLUM; CINGULATE GYRUS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG STRUCTURE; DRUG UPTAKE; FEMALE; FRONTAL CORTEX; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LATERAL TEMPORAL CORTEX; LIPOPHILICITY; MALE; MEDIAL TEMPORAL CORTEX; NONHUMAN; NORMAL HUMAN; OCCIPITAL CORTEX; PARIETAL CORTEX; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PUTAMEN; RECEPTOR BINDING; RHESUS MONKEY; TEMPORAL CORTEX; THALAMUS;

CANNABINOID; CB(1) RECEPTORS; PET; RECEPTOR IMAGING;

ADULT; ANIMALS; BRAIN; CARBON RADIOISOTOPES; FEMALE; HUMANS; MACACA MULATTA; MALE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTOR, CANNABINOID, CB1;

EID: 84885738234     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2013.09.043     Document Type: Article

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