-
1
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
DOI 10.1038/346561a0
-
LA Matsuda SJ Lolait MJ Brownstein AC Young TI Bonner 1990 Structure of a cannabinoid receptor and functional expression of the cloned cDNA Nature 346 561 564 10.1038/346561a0 1:CAS:528:DyaK3cXls1Ghu7w%3D 2165569 (Pubitemid 20238806)
-
(1990)
Nature
, vol.346
, Issue.6284
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
2
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
DOI 10.1038/365061a0
-
S Munro KL Thomas M Abu-Shaar 1993 Molecular characterization of a peripheral receptor for cannabinoids Nature 365 61 65 10.1038/365061a0 1:CAS:528:DyaK3sXmsVWiurk%3D 7689702 (Pubitemid 23305569)
-
(1993)
Nature
, vol.365
, Issue.6441
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
3
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
DOI 10.1124/pr.54.2.161
-
AC Howlett F Barth TI Bonner G Cabral P Casellas WA Devane, et al. 2002 International Union of Pharmacology. XXVII. Classification of cannabinoid receptors Pharmacol Rev 54 161 202 10.1124/pr.54.2.161 1:CAS:528: DC%2BD38XltVOiuro%3D 12037135 (Pubitemid 34575709)
-
(2002)
Pharmacological Reviews
, vol.54
, Issue.2
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
Mechoulam, R.11
Pertwee, R.G.12
-
4
-
-
51349141952
-
Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
-
10.1038/nm.f.1869 1:CAS:528:DC%2BD1cXhtVyms7vM 18776886
-
I Katona TF Freund 2008 Endocannabinoid signaling as a synaptic circuit breaker in neurological disease Nat Med 14 923 930 10.1038/nm.f.1869 1:CAS:528:DC%2BD1cXhtVyms7vM 18776886
-
(2008)
Nat Med
, vol.14
, pp. 923-930
-
-
Katona, I.1
Freund, T.F.2
-
5
-
-
4544275181
-
The endocannabinoid system and its therapeutic exploitation
-
DOI 10.1038/nrd1495
-
V Di Marzo M Bifulco L De Petrocellis 2004 The endocannabinoid system and its therapeutic exploitation Nat Rev Drug Discov 3 771 784 10.1038/nrd1495 15340387 (Pubitemid 39242829)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.9
, pp. 771-784
-
-
Di Marzo, V.1
Bifulco, M.2
De Petrocellis, L.3
-
6
-
-
17144382751
-
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-Year experience from the RIO-Europe study
-
DOI 10.1016/S0140-6736(05)66374-X
-
LF Van Gaal AM Rissanen AJ Scheen O Ziegler S Rossner 2005 Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study Lancet 365 1389 1397 10.1016/S0140-6736(05)66374-X 15836887 (Pubitemid 40523733)
-
(2005)
Lancet
, vol.365
, Issue.9468
, pp. 1389-1397
-
-
Van Gaal, L.F.1
Rissanen, A.M.2
Scheen, A.J.3
Ziegler, O.4
Rossner, S.5
-
7
-
-
37449007904
-
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake
-
10.1016/j.cmet.2007.11.012 1:CAS:528:DC%2BD1cXnsFSntw%3D%3D 18177726
-
C Addy H Wright K Van Laere I Gantz N Erondu BJ Musser, et al. 2008 The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake Cell Metab 7 68 78 10.1016/j.cmet.2007.11.012 1:CAS:528:DC%2BD1cXnsFSntw%3D%3D 18177726
-
(2008)
Cell Metab
, vol.7
, pp. 68-78
-
-
Addy, C.1
Wright, H.2
Van Laere, K.3
Gantz, I.4
Erondu, N.5
Musser, B.J.6
-
8
-
-
33845769902
-
1 receptor in the primate neocortex: A regional and laminar analysis
-
DOI 10.1093/cercor/bhj136
-
SM Eggan DA Lewis 2007 Immunocytochemical distribution of the cannabinoid CB1 receptor in the primate neocortex: a regional and laminar analysis Cereb Cortex 17 175 191 10.1093/cercor/bhj136 16467563 (Pubitemid 44973906)
-
(2007)
Cerebral Cortex
, vol.17
, Issue.1
, pp. 175-191
-
-
Eggan, S.M.1
Lewis, D.A.2
-
9
-
-
0025236913
-
Cannabinoid receptor localization in brain
-
M Herkenham AB Lynn MD Little MR Johnson LS Melvin BR de Costa, et al. 1990 Cannabinoid receptor localization in brain Proc Natl Acad Sci U S A 87 1932 1936 10.1073/pnas.87.5.1932 1:CAS:528:DyaK3cXhsFWktLs%3D 2308954 (Pubitemid 20098086)
-
(1990)
Proceedings of the National Academy of Sciences of the United States of America
, vol.87
, Issue.5
, pp. 1932-1936
-
-
Herkenham, M.1
Lynn, A.B.2
Little, M.D.3
Johnson, M.R.4
Melvin, L.S.5
De Coste, B.R.6
Rice, K.C.7
-
10
-
-
42749088228
-
Specific detection of CB1 receptors; Cannabinoid CB1 receptor antibodies are not all created equal!
-
10.1016/j.jneumeth.2008.02.014 1:CAS:528:DC%2BD1cXlvVSnsro%3D 18406468
-
NL Grimsey CE Goodfellow EL Scotter MJ Dowie M Glass ES Graham 2008 Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal! J Neurosci Methods 171 78 86 10.1016/j.jneumeth.2008.02.014 1:CAS:528:DC%2BD1cXlvVSnsro%3D 18406468
-
(2008)
J Neurosci Methods
, vol.171
, pp. 78-86
-
-
Grimsey, N.L.1
Goodfellow, C.E.2
Scotter, E.L.3
Dowie, M.J.4
Glass, M.5
Graham, E.S.6
-
11
-
-
59649092456
-
Development of radioligands for in vivo imaging of type 1 cannabinoid receptors (CB1) in human brain
-
10.2174/138161208786549380 1:CAS:528:DC%2BD1MXmtV2quw%3D%3D 19075713
-
AG Horti K Van Laere 2008 Development of radioligands for in vivo imaging of type 1 cannabinoid receptors (CB1) in human brain Curr Pharm Des 14 3363 3383 10.2174/138161208786549380 1:CAS:528:DC%2BD1MXmtV2quw%3D%3D 19075713
-
(2008)
Curr Pharm des
, vol.14
, pp. 3363-3383
-
-
Horti, A.G.1
Van Laere, K.2
-
12
-
-
34547559603
-
18F] fluoroethoxy)phenyl]-1-methylpropyl}-2-methyl-2-[(5-methylpyridin-2-yl)oxy] propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use
-
DOI 10.1021/jm070131b
-
P Liu LS Lin TG Hamill JP Jewell TJ Lanza Jr RE Gibson, et al. 2007 Discovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-[4-(2-[18F]fluoroethoxy)phenyl]-1- methylpropyl}- 2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use J Med Chem 50 3427 3430 10.1021/jm070131b 1:CAS:528:DC%2BD2sXns1Cgsr8%3D 17608398 (Pubitemid 47195451)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.15
, pp. 3427-3430
-
-
Liu, P.1
Lin, L.S.2
Hamill, T.G.3
Jewell, J.P.4
Lanza Jr., T.J.5
Gibson, R.E.6
Krause, S.M.7
Ryan, C.8
Eng, W.9
Sanabria, S.10
Tong, X.11
Wang, J.12
Levorse, D.A.13
Owens, K.A.14
Fong, T.M.15
Shen, C.-P.16
Lao, J.17
Kumar, S.18
Yin, W.19
Payack, J.F.20
Springfield, S.A.21
Hargreaves, R.22
Burns, H.D.23
Goulet, M.T.24
Hagmann, W.K.25
more..
-
13
-
-
34547411013
-
18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor
-
DOI 10.1073/pnas.0703472104
-
HD Burns K Van Laere S Sanabria-Bohorquez TG Hamill G Bormans WS Eng, et al. 2007 [18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor Proc Natl Acad Sci U S A 104 9800 9805 10.1073/pnas.0703472104 1:CAS:528:DC%2BD2sXmsFSmsLc%3D 17535893 (Pubitemid 47175347)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.23
, pp. 9800-9805
-
-
Burns, H.D.1
Van Laere, K.2
Sanabria-Bohorquez, S.3
Hamill, T.G.4
Bormans, G.5
Eng, W.-S.6
Gibson, R.7
Ryan, C.8
Connolly, B.9
Patel, S.10
Krause, S.11
Vanko, A.12
Van Hecken, A.13
Dupont, P.14
De Lepeleire, I.15
Rothenberg, P.16
Stoch, S.A.17
Cote, J.18
Hagmann, W.K.19
Jewell, J.P.20
Lin, L.S.21
Liu, P.22
Goulet, M.T.23
Gottesdiener, K.24
Wagner, J.A.25
De Hoon, J.26
Mortelmans, L.27
Fong, T.M.28
Hargreaves, R.J.29
more..
-
14
-
-
40449098011
-
18F-MK-9470 in healthy subjects
-
DOI 10.2967/jnumed.107.047290
-
K Van Laere M Koole SM Sanabria Bohórquez K Goffin I Guenther MJ Belanger, et al. 2008 Whole-body biodistribution and radiation dosimetry of the human cannabinoid type-1 receptor ligand 18F-MK-9470 in healthy subjects J Nucl Med 49 439 445 10.2967/jnumed.107.047290 18287275 (Pubitemid 351355210)
-
(2008)
Journal of Nuclear Medicine
, vol.49
, Issue.3
, pp. 439-445
-
-
Van Laere, K.1
Koole, M.2
Bohorquez, S.M.S.3
Goffin, K.4
Guenther, I.5
Belanger, M.J.6
Cote, J.7
Rothenberg, P.8
De Lepeleire, I.9
Grachev, I.D.10
Hargreaves, R.J.11
Bormans, G.12
Burns, H.D.13
-
15
-
-
38749128371
-
Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET
-
10.1016/j.neuroimage.2007.10.053 18077184
-
K Van Laere K Goffin C Casteels P Dupont L Mortelmans J de Hoon, et al. 2008 Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET Neuroimage 39 1533 1541 10.1016/j.neuroimage.2007.10.053 18077184
-
(2008)
Neuroimage
, vol.39
, pp. 1533-1541
-
-
Van Laere, K.1
Goffin, K.2
Casteels, C.3
Dupont, P.4
Mortelmans, L.5
De Hoon, J.6
-
16
-
-
0028700063
-
Accelerated image reconstruction using ordered subsets of projection data
-
10.1109/42.363108 1:STN:280:DC%2BD1c%2FmsFCkuw%3D%3D 18218538
-
HM Hudson RS Larkin 1994 Accelerated image reconstruction using ordered subsets of projection data IEEE Trans Med Imaging 13 601 609 10.1109/42.363108 1:STN:280:DC%2BD1c%2FmsFCkuw%3D%3D 18218538
-
(1994)
IEEE Trans Med Imaging
, vol.13
, pp. 601-609
-
-
Hudson, H.M.1
Larkin, R.S.2
-
17
-
-
14844298745
-
Regional cerebral blood flow responses to smoking in tobacco smokers after overnight abstinence
-
DOI 10.1176/appi.ajp.162.3.567
-
JK Zubieta MM Heitzeg Y Xu RA Koeppe L Ni S Guthrie, et al. 2005 Regional cerebral blood flow responses to smoking in tobacco smokers after overnight abstinence Am J Psychiatry 162 567 577 10.1176/appi.ajp.162.3.567 15741475 (Pubitemid 40343925)
-
(2005)
American Journal of Psychiatry
, vol.162
, Issue.3
, pp. 567-577
-
-
Zubieta, J.-K.1
Heitzeg, M.M.2
Xu, Y.3
Koeppe, R.A.4
Ni, L.5
Guthrie, S.6
Domino, E.F.7
-
18
-
-
34247636712
-
Regional cerebral blood flow during gastric balloon distention in functional dyspepsia
-
DOI 10.1053/j.gastro.2007.03.037, PII S0016508507005616
-
J Vandenberghe P Dupont L Van Oudenhove G Bormans K Demyttenaere B Fischler, et al. 2007 Regional cerebral blood flow during gastric balloon distention in functional dyspepsia Gastroenterology 132 1684 1693 10.1053/j.gastro.2007.03.037 17484866 (Pubitemid 46677948)
-
(2007)
Gastroenterology
, vol.132
, Issue.5
, pp. 1684-1693
-
-
Vandenberghe, J.1
Dupont, P.2
Van Oudenhove, L.3
Bormans, G.4
Demyttenaere, K.5
Fischler, B.6
Geeraerts, B.7
Janssens, J.8
Tack, J.9
-
20
-
-
12444347361
-
11C]flumazenil kinetic analysis in human brain
-
DOI 10.1016/S1536-1632(03)00046-5, PII S1536163203000465
-
SM Sanabria-Bohórquez A Maes P Dupont G Bormans T de Groot A Coimbra, et al. 2003 Image-derived input function for [11C]flumazenil kinetic analysis in human brain Mol Imaging Biol 5 72 78 10.1016/S1536-1632(03)00046-5 14499147 (Pubitemid 36676013)
-
(2003)
Molecular Imaging and Biology
, vol.5
, Issue.2
, pp. 72-78
-
-
Sanabria-Bohorquez, S.M.1
Maes, A.2
Dupont, P.3
Bormans, G.4
De Groot, T.5
Coimbra, A.6
Eng, W.7
Laethem, T.8
De Lepeleire, I.9
Gambale, J.10
Vega, J.M.11
Burns, H.D.12
-
21
-
-
0025455847
-
Identifiability analysis and parameter identification of an in vivo ligand-receptor model from PET data
-
DOI 10.1109/10.55673
-
J Delforge A Syrota BM Mazoyer 1990 Identifiability analysis and parameter identification of an in vivo ligand-receptor model from PET data IEEE Trans Biomed Eng 37 653 661 10.1109/10.55673 1:STN:280:DyaK3czmvVWjsA%3D%3D 2394453 (Pubitemid 20293265)
-
(1990)
IEEE Transactions on Biomedical Engineering
, vol.37
, Issue.7
, pp. 653-661
-
-
Delforge, J.1
Syrota, A.2
Mazoyer, B.M.3
-
24
-
-
0028285918
-
Effects of hyperglycemia on FDG uptake in human brain and glioma
-
K Ishizu S Nishizawa Y Yonekura N Sadato Y Magata N Tamaki, et al. 1994 Effects of hyperglycemia on FDG uptake in human brain and glioma J Nucl Med 35 1104 1109 1:CAS:528:DyaK2cXlsFags7s%3D 8014665 (Pubitemid 24204108)
-
(1994)
Journal of Nuclear Medicine
, vol.35
, Issue.7
, pp. 1104-1109
-
-
Ishizu, K.1
Nishizawa, S.2
Yonekura, Y.3
Sadato, N.4
Magata, Y.5
Tamaki, N.6
Tsuchida, T.7
Okazawa, H.8
Miyatake, S.-I.9
Ishikawa, M.10
Kikuchi, H.11
Konishi, J.12
-
25
-
-
0029287133
-
Clarification of a fractional uptake concept
-
1:STN:280:DyaK2M3htlyhtA%3D%3D 7699475
-
JA Thie 1995 Clarification of a fractional uptake concept J Nucl Med 36 711 712 1:STN:280:DyaK2M3htlyhtA%3D%3D 7699475
-
(1995)
J Nucl Med
, vol.36
, pp. 711-712
-
-
Thie, J.A.1
-
26
-
-
0033729522
-
Graphical analysis of PET data applied to reversible and irreversible tracers
-
10.1016/S0969-8051(00)00137-2 1:STN:280:DC%2BD3M7htVyltw%3D%3D 11091109
-
J Logan 2000 Graphical analysis of PET data applied to reversible and irreversible tracers Nucl Med Biol 27 661 670 10.1016/S0969-8051(00)00137-2 1:STN:280:DC%2BD3M7htVyltw%3D%3D 11091109
-
(2000)
Nucl Med Biol
, vol.27
, pp. 661-670
-
-
Logan, J.1
-
27
-
-
68749088245
-
Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand
-
10.1016/j.neuroimage.2009.06.059 19573609
-
GE Terry J Liow SS Zoghbi J Hirvonen AG Farris A Lerner, et al. 2009 Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand Neuroimage 48 362 370 10.1016/j.neuroimage.2009.06.059 19573609
-
(2009)
Neuroimage
, vol.48
, pp. 362-370
-
-
Terry, G.E.1
Liow, J.2
Zoghbi, S.S.3
Hirvonen, J.4
Farris, A.G.5
Lerner, A.6
-
28
-
-
0029069587
-
Selective reduction of radiotracer trapping by deuterium substitution: Comparison of carbon-11-L-deprenyl and carbon-11-deprenyl-D2 for MAO B mapping
-
1:CAS:528:DyaK2MXntFSjtbc%3D 7790952
-
JS Fowler GJ Wang J Logan S Xie ND Volkow RR MacGregor, et al. 1995 Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-deprenyl and carbon-11-deprenyl-D2 for MAO B mapping J Nucl Med 36 1255 1262 1:CAS:528:DyaK2MXntFSjtbc%3D 7790952
-
(1995)
J Nucl Med
, vol.36
, pp. 1255-1262
-
-
Fowler, J.S.1
Wang, G.J.2
Logan, J.3
Xie, S.4
Volkow, N.D.5
MacGregor, R.R.6
-
29
-
-
77952099390
-
Imaging and quantification of cannabinoid CB1 receptors in human and monkey brain using 18F-labeled inverse agonist radioligands
-
in press
-
Terry GE, Hiervonen J, Liow JS, Zoghbi SS, Gladding R, Tauscher JT, et al. Imaging and quantification of cannabinoid CB1 receptors in human and monkey brain using 18F-labeled inverse agonist radioligands. J Nucl Med 2009;in press.
-
(2009)
J Nucl Med
-
-
Terry, G.E.1
Hiervonen, J.2
Liow, J.S.3
Zoghbi, S.S.4
Gladding, R.5
Tauscher, J.T.6
-
30
-
-
0031047273
-
Cannabinoid receptors in the human brain: A detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain
-
DOI 10.1016/S0306-4522(96)00428-9, PII S0306452296004289
-
M Glass M Dragunow RL Faull 1997 Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain Neuroscience 77 299 318 10.1016/S0306-4522(96)00428-9 1:CAS:528:DyaK2sXhs1Gms7w%3D 9472392 (Pubitemid 27079604)
-
(1997)
Neuroscience
, vol.77
, Issue.2
, pp. 299-318
-
-
Glass, M.1
Dragunow, M.2
Faull, R.L.M.3
|