Pulmonary hypertension after hematopoietic stem cell transplantation

Biology of Blood and Marrow Transplantation

Volumn 19, Issue 11, 2013, Pages 1546-1556

  Dandoy, Christopher E ^a   Hirsch, Russel ^a   Chima, Ranjit ^a   Davies, Stella M ^a   Jodele, Sonata ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Pulmonary arterial hypertension; Pulmonary hypertension; Pulmonary veno occlusive disease; Thrombotic microangiopathy

Indexed keywords

ANGIOPOIETIN 2; BERAPROST; BONE MORPHOGENETIC PROTEIN 9; BRAIN NATRIURETIC PEPTIDE; DEFIBROTIDE; ENDOTHELIN 1; METHYLPREDNISOLONE; N(G),N(G) DIMETHYLARGININE; NICARDIPINE; PENTRAXIN 3; PROSTACYCLIN; SILDENAFIL; TRANSFORMING GROWTH FACTOR BETA; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

ADOLESCENT; ANTICOAGULANT THERAPY; BRONCHIOLITIS OBLITERANS; CHILD; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPUTER ASSISTED TOMOGRAPHY; DIASTOLIC DYSFUNCTION; DIFFERENTIAL DIAGNOSIS; DISEASE CLASSIFICATION; DYSPNEA; ECHOCARDIOGRAPHY; EDEMA; ELECTROCARDIOGRAPHY; FAINTNESS; FAMILY HISTORY; FATTY ACID DESATURATION; FEMALE; GAUCHER DISEASE; GLYCOGEN STORAGE DISEASE; HEART CATHETERIZATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMODYNAMICS; HUMAN; HUMAN TISSUE; HYPOXIA; INFANT; INTERSTITIAL LUNG DISEASE; INTERSTITIAL PNEUMONIA; LANGERHANS CELL HISTIOCYTOSIS; LUNG ALVEOLUS HYPOVENTILATION; LUNG ARTERY PRESSURE; LUNG SARCOIDOSIS; LUNG VASCULAR RESISTANCE; MAJOR CLINICAL STUDY; MALE; MYELOPROLIFERATIVE DISORDER; NUCLEAR MAGNETIC RESONANCE IMAGING; ORGANIZING PNEUMONIA; OXYGEN THERAPY; PATHOPHYSIOLOGY; PRESCHOOL CHILD; PULMONARY ARTERY; PULMONARY HYPERTENSION; RESPIRATORY DISTRESS; RESPIRATORY FAILURE; REVIEW; SCHOOL CHILD; SLEEP DISORDERED BREATHING; SYSTOLIC DYSFUNCTION; TACHYPNEA; THORAX RADIOGRAPHY; THROMBOEMBOLISM; THROMBOTIC THROMBOCYTOPENIC PURPURA; VALVULAR HEART DISEASE; VEIN OCCLUSION;

PULMONARY ARTERIAL HYPERTENSION; PULMONARY HYPERTENSION; PULMONARY VENO-OCCLUSIVE DISEASE; THROMBOTIC MICROANGIOPATHY;

HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; HYPERTENSION, PULMONARY; RISK FACTORS; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, AUTOLOGOUS;

EID: 84885731580     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2013.07.017     Document Type: Review

References (73)

1. Troussard X.B.J., Cordonnier C., Fleury J., et al. Pulmonary veno-occlusive disease after bone marrow transplantation. Thorax 1984, 39:956-957.
2. Hackman R.M.D., Petersen F., Clark J. Pulmonary venoocclusive disease following bone marrow transplantation. Transplantation 1989, 47:989-992.
3. Bruckmann C.L.W., Roos R., Permanetter W., et al. Severe pulmonary vascular occlusive disease following bone marrow transplantation in Omenn syndrome. Eur J Pediatr 1991, 150:242-245.
4. Kuga T., Kohda K., Hirayama Y., et al. Pulmonary veno-occlusive disease accompanied by microangiopathic hemolytic anemia 1 year after a second bone marrow transplantation for acute lymphoblastic leukemia. Int J Hematol 1996, 64:143-150.
5. Williams L.M., Nelson S., Mason C.M., et al. Pulmonary veno-occlusive disease in an adult following bone marrow transplantation case report and review of the literature. CHEST J 1996, 109:1388-1391.
6. Seguchi M.H.N., Fujii Y., Azuno Y., et al. Pulmonary hypertension associated with pulmonary occlusive vasculopathy after allogeneic bone marrow transplantation. Transplantation 2000, 69:177-179.
7. Vaksmann G., Nelken B., Deshildre A., Rey C. Pulmonary arterial occlusive disease following chemotherapy and bone marrow transplantation for leukaemia. Eur J Pediatr 2002, 161:247-249.
8. Mukai M., Kondo M., Bohgaki T., et al. Pulmonary veno-occlusive disease following allogeneic peripheral blood stem cell transplantation for chronic myeloid leukaemia. Br J Haematol 2003, 123(1):1.
9. Trobaugh-Lotrario A.D., Greffe B., Deterding R., et al. Pulmonary veno-occlusive disease after autologous bone marrow transplant in a child with stage IV neuroblastoma: Case report and literature review. JPediatr Hematol Oncol 2003, 25:405-409.
10. Shankar S., Choi J.K., Dermody T.S., et al. Pulmonary hypertension complicating bone marrow transplantation for idiopathic myelofibrosis. JPediatr Hematol Oncol 2004, 26:393-397.
11. Steward C.G., Pellier I., Mahajan A., et al. Severe pulmonary hypertension: A frequent complication of stem cell transplantation for malignant infantile osteopetrosis. Br J Haematol 2004, 124:63-71.
12. Malhotra P., Varma S., Varma N., et al. Pulmonary veno-occlusive disease as a cause for reversible pulmonary hypertension in a patient with multiple myeloma undergoing peripheral blood stem cell transplantation. Am J Hematol 2005, 80:164-165.
13. Grigg A., Buchanan M., Whitford H. Late-onset pulmonary arterial hypertension in association with graft-versus-host disease after allogeneic stem-cell transplantation. Am J Hematol 2005, 80:38-42.
14. Limsuwan A., Pakakasama S., Rochanawutanon M., Hong-eng S. Pulmonary arterial hypertension after childhood cancer therapy and bone marrow transplantation. Cardiology 2006, 105:188-194.
15. Perkowska-Ptasinska A., Sulikowska-Rowinska A., Pazik J., et al. Thrombotic nephropathy and pulmonary hypertension following autologous bone marrow transplantation in a patient with acute lymphoblastic leukemia: Case report. Transplant Proc 2006, 38:295-296.
16. Gutman J.A.A.C., Madtes D.K., Schramm J., Delaney C. Pulmonary veno-occlusive disease following reduced-intensity cord blood transplantation. Bone Marrow Transplant 2008, 42:559.
17. Nakaoka H., Sakata Y., Yamamoto M., et al. Pulmonary hypertension associated with bone marrow transplantation. JCardiol Cases 2010, 2:e23-e27.
18. Limsuwan A., Pakakasama S., Hongeng S. Reversible course of pulmonary arterial hypertension related to bone marrow transplantation. Heart Vessels 2011, 26:557-561.
19. Hosokawa K.Y.H., Nishitsuji M., Kobayashi S., et al. Pulmonary veno-occlusive disease following reduced-intensity allogeneic bone marrow transplantation for acute myeloid leukemia. Intern Med 2012, 51:195-198.
20. Kawashima N., Ikoma M., Sekiya Y., et al. Successful treatment of pulmonary hypertension with beraprost and sildenafil after cord blood transplantation for infantile leukemia. Int J Hematol 2012, 1-4.
21. Zeilhofer U., Ashworth M., Amrolia P., et al. Pulmonary hypertension following haematopoietic stem cell transplantation for primary haemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2013, 60:521-523.
22. Jodele S., Hirsch R., Laskin B., et al. Pulmonary arterial hypertension in pediatric patients with hematopoietic stem cell transplant-associated thrombotic microangiopathy. Biol Blood Marrow Transplant 2013, 19:202-207.
23. Schechter T., Leucht S., Bouffet E., et al. Pulmonary hypertensive vasculopathy following tandem autologous transplantation in pediatric patients with central nervous system tumors. Biol Blood Marrow Transplant 2013, 19:235-239.
24. Soubani A.O.M.K., Hassoun P.M. Pulmonary complications of bone marrow transplantation. Chest 1996, 109:1066-1077.
25. MacNee W. Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part One. Am J Respir Crit Care Med 1994, 150:833-852.
26. Apostolakis S., Konstantinides S. The right ventricle in health and disease: Insights into physiology, pathophysiology and diagnostic management. Cardiology 2012, 121:263-273.
27. Bossone E., Bodini B.D., Mazza A., Allegra L. Pulmonary arterial hypertension: The key role of echocardiography. CHEST J 2005, 127:1836-1843.
28. Bossone E., D'Andrea A., D'Alto M., et al. Echocardiography in pulmonary arterial hypertension: From diagnosis to prognosis. JAm Soc Echocardiogr 2013, 26:1-14.
29. Members A.T.F., Galiè N., Hoeper M.M., et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 2009, 30:2493-2537.
30. Schannwell C.M.S.S., Strauer B.E. Diagnostics in pulmonary hypertension. JPhysiol Pharmacol 2007, 58:591-602.
31. Rosenzweig E.B., Barst R. Pulmonary arterial hypertension in children: A medical update. Curr Opin Pediatr 2008, 20:288-293.
32. Houtchens J., Martin D., Klinger J.R. Diagnosis and management of pulmonary arterial hypertension. Pulmonary Med 2011, 2011:845-864.
33. Rabinovitch M. Molecular pathogenesis of pulmonary arterial hypertension. JClin Invest 2012, 122:4306-4313.
34. Wahl S.V.E. Pulmonary hypertension in hemolytic anemias. Med Rep 2010, 2:10. 10.3410/M2-10.
35. Hill A., Sapsford R.J., Scally A., et al. Under-recognized complications in patients with paroxysmal nocturnal haemoglobinuria: Raised pulmonary pressure and reduced right ventricular function. Br J Haematol 2012, 158:409-414.
36. Laskin B.L., Goebel J., Davies S.M., Jodele S. Small vessels, big trouble in the kidneys and beyond: Hematopoietic stem cell transplantation-associated thrombotic microangiopathy. Blood 2011, 118:1452-1462.
37. Jodele S., Licht C., Goebel J., et al. Abnormalities in the alternative pathway of complement in children with hematopoietic stem cell transplant-associated thrombotic microangiopathy. Blood 2013, 10.1182/blood-2013-05-501445.
38. Heath D.S.N., Bishop J. Pulmonary veno-occlusive disease. Circulation 1966, 34:242-248.
39. Montani D., Price L.C., Dorfmuller P., et al. Pulmonary veno-occlusive disease. Eur Respir J 2009, 33:189-200.
40. Simonneau G., Robbins I.M., Beghetti M., et al. Updated clinical classification of pulmonary hypertension. JAm Coll Cardiol 2009, 54(1 Suppl):S43-S54.
41. Holcomb B.W., Loyd J.E., Ely E.W., et al. Pulmonary veno-occlusive disease. CHEST 2000, 118:1671.
42. Murdych T., Weisdorf D.J. Serious cardiac complications during bone marrow transplantation at the University of Minnesota, 1977-1997. Bone Marrow Transplant 2001, 28:283-287.
43. Ueda K.W.T., Maeda E., Ota S., et al. Outcome and treatment of late-onset noninfectious pulmonary complications after allogeneic haematopoietic SCT. Bone Marrow Transplant 2010, 45:1719-1727.
44. Nathan S.D., Shlobin O.A., Ahmad S., et al. Pulmonary hypertension in patients with bronchiolitis obliterans syndrome listed for retransplantation. Am J Transplant 2008, 8:1506-1511.
45. Hopkins N., McLoughlin P. The structural basis of pulmonary hypertension in chronic lung disease: Remodelling, rarefaction or angiogenesis?. JAnat 2002, 201:335-348.
46. Dingli D., Utz J.P., Krowka M.J., et al. Unexplained pulmonary hypertension in chronic myeloproliferative disorders. CHEST J 2001, 120:801-808.
47. Jaïs X., Ioos V., Jardim C., et al. Splenectomy and chronic thromboembolic pulmonary hypertension. Thorax 2005, 60:1031-1034.
48. Suri H., Yi E., Nowakowski G., Vassallo R. Pulmonary Langerhans cell histiocytosis. Orph J Rare Dis 2012, 7:16.
49. Corte T.J., Wells A.U., Nicholson A.G., et al. Pulmonary hypertension in sarcoidosis: A review. Respirology 2011, 16:69-77.
50. Mistry P.K., Sirrs S., Chan A., et al. Pulmonary hypertension in type 1 Gaucher's disease: Genetic and epigenetic determinants of phenotype and response to therapy. Mol Genet Metab 2002, 77:91-98.
51. Kramer M.R., Estenne M., Berkman N., et al. Radiation-induced pulmonary veno-occlusive disease. CHEST J 1993, 104:1282-1284.
52. Bunte M.C.P.M., Pritzker M., Burns L. Pulmonary veno-occlusive disease following hematopoietic stem cell transplantation: A rare model of endothelial dysfunction. Bone Marrow Transplant 2008, 41:677-686.
53. Pietra G.G., Capron F., Stewart S., et al. Pathologic assessment of vasculopathies in pulmonary hypertension. JAm Coll Cardiol 2004, 43(12 Suppl.):S25-S32.
54. Tuder R.M., Abman S.H., Braun T., et al. Development and pathology of pulmonary hypertension. JAm Coll Cardiol 2009, 54(1 Suppl.):S3-S9.
55. Miura A., Akagi S., Nakamura K., et al. Different sizes of centrilobular ground-glass opacities in chest high-resolution computed tomography of patients with pulmonary veno-occlusive disease and patients with pulmonary capillary hemangiomatosis. Cardiovasc Pathol 2013, 22(4):287-293.
56. Panoskaltsis-Mortari A., Griese M., Madtes D.K., et al. An official American Thoracic Society research statement: Noninfectious lung injury after hematopoietic stem cell transplantation: Idiopathic pneumonia syndrome. Am J Respir Crit Care Med 2011, 183:1262-1279.
57. Chima R.S., Abulebda K., Jodele S. Advances in critical care of the pediatric hematopoietic stem cell transplant patient. Pediatr Clin North Am 2013, 60:689-707.
58. Rich S., Dantzker D.R., Ayres S.M., et al. Primary pulmonary hypertension: A national prospective study. Ann Intern Med 1987, 107:216-223.
59. Ahearn G.S., Tapson V.F., Rebeiz A., Greenfield J.J.C. Electrocardiography to define clinical status in primary pulmonary hypertension and pulmonary arterial hypertension secondary to collagen vascular disease. CHEST J 2002, 122:524-527.
60. Stevens G.R., Fida N., Sanz J. Computed tomography and cardiac magnetic resonance imaging in pulmonary hypertension. Progr Cardiovasc Dis 2012, 55:161-171.
61. Resten A., Maitre S., Humbert M., et al. Pulmonary hypertension: CT of the chest in pulmonary venoocclusive disease. AJR. Am J Roentgenol 2004, 183:65-70.
62. Okajima Y.O.Y., Washko G., Hatabu H. Assessment of pulmonary hypertension: What CT and MRI can provide. Acad Radiol 2011, 18:437-453.
63. Milan A., Magnino C., Veglio F. Echocardiographic indexes for the non-invasive evaluation of pulmonary hemodynamics. JAm Soc Echocardiogr 2010, 23:225-239.
64. Ventetuolo C.E., Klinger J.R. WHO Group 1 pulmonary arterial hypertension: Current and investigative therapies. Progr Cardiovasc Dis 2012, 55:89-103.
65. Fuster V., Steele P.M., Edwards W.D., et al. Primary pulmonary hypertension: Natural history and the importance of thrombosis. Circulation 1984, 70:580-587.
66. Roberts D.H., Lepore J.J., Maroo A., et al. Oxygen therapy improves cardiac index and pulmonary vascular resistance in patients with pulmonary hypertension. CHEST 2001, 120:1547.
67. Checchia P.A., Bronicki R.A., Goldstein B. Review of inhaled nitric oxide in the pediatric cardiac surgery setting. Pediatr Cardiol 2012, 33:493-505.
68. Tonelli A.R., Alnuaimat H., Mubarak K. Pulmonary vasodilator testing and use of calcium channel blockers in pulmonary arterial hypertension. Respir Med 2010, 104:481-496.
69. Raja S.G.R.S. Treating pulmonary arterial hypertension: Current treatments and future prospects. Ther Adv Chron Dis 2011, 2:359-370.
70. Dupuis J., Hoeper M.M. Endothelin receptor antagonists in pulmonary arterial hypertension. Eur Respir J 2008, 31:407-415.
71. Members W.C., McLaughlin V.V., Archer S.L., et al. ACCF/AHA 2009Expert consensus document on pulmonary hypertension: A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: Developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation 2009, 119:2250-2294.
72. Sitbon O., Humbert M., Nunes H., et al. Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival. JAm Coll Cardiol 2002, 40:780-788.
73. Olschewski H., Walmrath D., Schermuly R., et al. Aerosolized prostacyclin and iloprost in severe pulmonary hypertension. Ann Intern Med 1996, 124:820-824.