Hemoglobin Vesicles as a Cellular-Type Hemoglobin-Based Oxygen Carrier

Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood

Volumn , Issue , 2011, Pages 381-390

  Sakai, Hiromi ^a,b   Horinouchi, Hirohisa ^c   Tsuchida, Eishun ^b   Kobayashi, Koichi ^c  

^a Waseda University   (Singapore)

^b WASEDA UNIVERSITY   (Japan)

^c KEIO UNIVERSITY   (Japan)

Author keywords

Chemically modified cell free Hb based oxygen carriers (HBOCs) polymer conjugated Hbs; CO, toxic gaseous molecule cytoprotective effect depending on dose; Concept of Hb encapsulation in liposomes; Encapsulation of Hb in vesicles retarding NO binding; Hb encapsulation retards gas reactions vasoconstriction, hypertension; HBOCs as a carrier of O2 and CO HBOCs as CO carriers; HbVs, artificial oxygen carriers encapsulating concentrated Hb solution; Hemoglobin (Hb), most abundant protein in blood essential protein; Hemoglobin vesicles a cellular type hemoglobin based oxygen carrier; Preclinical studies of HbV as transfusion alternative, and other therapeutics

Indexed keywords

EID: 84885719281     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781119975427.ch27     Document Type: Chapter

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