Ubiquitination-mediated autophagy against invading bacteria

Current Opinion in Cell Biology

Volumn 23, Issue 4, 2011, Pages 492-497

  Fujita, Naonobu ^a,b   Yoshimori, Tamotsu ^a,b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3;

AUTOPHAGY; BACTERIUM COLONY; CELL INVASION; DRUG TARGETING; ENDOCYTOSIS; ENDOSOME; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; LYSOSOME; MAMMAL CELL; MITOCHONDRION; NONHUMAN; PEROXISOME; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; REVIEW; UBIQUITINATION;

ANIMALS; AUTOPHAGY; BACTERIA; BACTERIAL INFECTIONS; HUMANS; LYSOSOMES; UBIQUITIN; UBIQUITINATION;

MAMMALIA;

EID: 79960735619     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2011.03.003     Document Type: Review

References (35)

1. Yoshimori T., Noda T. Toward unraveling membrane biogenesis in mammalian autophagy. Curr Opin Cell Biol 2008, 20:401-407.
2. Mizushima N., Levine B., Cuervo A.M., Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 2008, 451:1069-1075.
3. Komatsu M., Ichimura Y. Selective autophagy regulates various cellular functions. Genes Cells 2010, 15:923-933.
4. Shahnazari S., Brumell J.H. Mechanisms and consequences of bacterial targeting by the autophagy pathway. Curr Opin Microbiol 2011, 14:68-75.
5. Ciechanover A., Iwai K. The ubiquitin system: from basic mechanisms to the patient bed. IUBMB Life 2004, 56:193-201.
6. Yamaguchi H., Nakagawa I., Yamamoto A., Amano A., Noda T., Yoshimori T. An initial step of GAS-containing autophagosome-like vacuoles formation requires Rab7. PLoS Pathog 2009, 5:e1000670.
7. Collins C.A., De Maziere A., van Dijk S., Carlsson F., Klumperman J., Brown E.J. Atg5-independent sequestration of ubiquitinated mycobacteria. PLoS Pathog 2009, 5:e1000430.
8. Yoshikawa Y., Ogawa M., Hain T., Yoshida M., Fukumatsu M., Kim M., Mimuro H., Nakagawa I., Yanagawa T., Ishii T., et al. Listeria monocytogenes ActA-mediated escape from autophagic recognition. Nat Cell Biol 2009, 11:1233-1240.
9. Thurston T.L., Ryzhakov G., Bloor S., von Muhlinen N., Randow F. The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat Immunol 2009, 10:1215-1221.
10. Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010, 11:373-384.
11. Cossart P., Roy C.R. Manipulation of host membrane machinery by bacterial pathogens. Curr Opin Cell Biol 2010, 22:547-554.
12. Dupont N., Lacas-Gervais S., Bertout J., Paz I., Freche B., Van Nhieu G.T., van der Goot F.G., Sansonetti P.J., Lafont F. Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy. Cell Host Microbe 2009, 6:137-149.
13. Ogawa M., Yoshimori T., Suzuki T., Sagara H., Mizushima N., Sasakawa C. Escape of intracellular Shigella from autophagy. Science 2005, 307:727-731.
14. Zheng Y.T., Shahnazari S., Brech A., Lamark T., Johansen T., Brumell J.H. The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. J Immunol 2009, 183:5909-5916.
15. Birmingham C.L., Smith A.C., Bakowski M.A., Yoshimori T., Brumell J.H. Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole. J Biol Chem 2006, 281:11374-11383.
16. Ponpuak M., Davis A.S., Roberts E.A., Delgado M.A., Dinkins C., Zhao Z., Virgin HWt, Kyei G.B., Johansen T., Vergne I., et al. Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. Immunity 2010, 32:329-341.
17. Hanada T., Noda N.N., Satomi Y., Ichimura Y., Fujioka Y., Takao T., Inagaki F., Ohusmi Y. The ATG12-ATG5 conjugate has a novel e3-like activity for protein lipidation in autophagy. J Biol Chem 2007, 282:37298-37302.
18. Fujita N., Itoh T., Fukuda M., Noda T., Yoshimori T. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 2008, 19:2092-2100.
19. Ichimura Y., Kirisako T., Takao T., Satomi Y., Shimonishi Y., Ishihara N., Mizushima N., Tanida I., Kominami E., Ohsumi M., et al. A ubiquitin-like system mediates protein lipidation. Nature 2000, 408:488-492.
20. Kabeya Y., Mizushima N., Ueno T., Yamamoto A., Kirisako T., Noda T., Kominami E., Ohsumi Y., Yoshimori T. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000, 19:5720-5728.
21. Kirisako T., Ichimura Y., Okada H., Kabeya Y., Mizushima N., Yoshimori T., Ohsumi M., Takao T., Noda T., Ohsumi Y. The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 2000, 151:263-276.
22. Kirkin V., McEwan D.G., Novak I., Dikic I. A role for ubiquitin in selective autophagy. Mol Cell 2009, 34:259-269.
23. Cemma M., Kim P.K., Brumell J.H. The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway. Autophagy 2011, 7:22-26.
24. Kim P.K., Hailey D.W., Mullen R.T., Lippincott-Schwartz J. Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes. Proc Natl Acad Sci USA 2008, 105:20567-20574.
25. Geisler S., Holmstrom K.M., Skujat D., Fiesel F.C., Rothfuss O.C., Kahle P.J., Springer W. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 2010, 12:119-131.
26. Tanaka A. Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network. FEBS Lett 2010, 584:1386-1392.
27. Narendra D., Kane L.A., Hauser D.N., Fearnley I.M., Youle R.J. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy 2010, 6:1090-1106.
28. Okatsu K., Saisho K., Shimanuki M., Nakada K., Shitara H., Sou Y.S., Kimura M., Sato S., Hattori N., Komatsu M., et al. p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria. Genes Cells 2010, 15:887-900.
29. Itakura E., Mizushima N. Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 2010, 6:764-776.
30. Suzuki K., Kubota Y., Sekito T., Ohsumi Y. Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 2007, 12:209-218.
31. Suzuki K., Kamada Y., Ohsumi Y. Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae. Dev Cell 2002, 3:815-824.
32. Shintani T., Huang W.P., Stromhaug P.E., Klionsky D.J. Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway. Dev Cell 2002, 3:825-837.
33. Suzuki K., Kondo C., Morimoto M., Ohsumi Y. Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p. J Biol Chem 2010, 285:30019-30025.
34. Okamoto K., Kondo-Okamoto N., Ohsumi Y. Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 2009, 17:87-97.
35. Kanki T., Wang K., Cao Y., Baba M., Klionsky D.J. Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 2009, 17:98-109.