Novel biphasic role of resolvin D1 on expression of cyclooxygenase-2 in LIPOPOLYSACCHARIDE-STIMULATED LUNG FIBROBLASTS IS PARTLY THROUGH PI3K/AKT and ERK2 pathways

Mediators of Inflammation

Volumn 2013, Issue , 2013, Pages

  Wu, Derong ^a   Zheng, Shengxing ^a   Li, Wenjuan ^a   Yang, Li ^a   Liu, Yongjian ^a   Zheng, Xia ^a   Yang, Yi ^a   Yang, Liangmin ^a   Wang, Qian ^a   Smith, Fang Gao ^b   Jin, Shengwei ^a  

^a THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INTERLEUKIN 8; LIPID; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROTEIN KINASE B; RESOLVIN D1; UNCLASSIFIED DRUG; AKT1 PROTEIN, HUMAN; AKT1 PROTEIN, RAT; CCL2 PROTEIN, HUMAN; CCL2 PROTEIN, RAT; DOCOSAHEXAENOIC ACID; MAPK1 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; PTGS2 PROTEIN, RAT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LUNG FIBROBLAST; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; ANIMAL; CELL LINE; FIBROBLAST; GENE EXPRESSION REGULATION; LUNG; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CHEMOKINE CCL2; CYCLOOXYGENASE 2; DINOPROSTONE; DOCOSAHEXAENOIC ACIDS; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; LUNG; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3-KINASES; PROSTAGLANDIN D2; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION;

EID: 84885649234     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/964012     Document Type: Article

References (48)

1. Pugin J., Verghese G., Widmer M., Matthay M. A., The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Critical Care Medicine 1999 27 2 304 312 2-s2.0-0032911805 (Pubitemid 29113539)
2. Ware L. B., Matthay M. A., Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. The American Journal of Physiology-Lung Cellular and Molecular Physiology 2002 282 5 L924 L940 2-s2.0-0036080893 (Pubitemid 34654608)
3. Buckley C. D., Why does chronic inflammation persist: an unexpected role for fibroblasts. Immunology Letters 2011 138 1 12 14 2-s2.0-79957774659 10.1016/j.imlet.2011.02.010
4. Quesnel C., Marchand-Adam S., Fabre A., Marchal-Somme J., Philip I., Lasocki S., Leçon V., Crestani B., Dehoux M., Regulation of hepatocyte growth factor secretion by fibroblasts in patients with acute lung injury. The American Journal of Physiology-Lung Cellular and Molecular Physiology 2008 294 2 L334 L343 2-s2.0-39149141033 10.1152/ajplung.00096.2007 (Pubitemid 351253370)
5. Selige J., Tenor H., Hatzelmann A., Dunkern T., Cytokine-dependent balance of mitogenic effects in primary human lung fibroblasts related to cyclic AMP signaling and phosphodiesterase 4 inhibition. Journal of Cellular Physiology 2010 223 2 317 326
6. Smith R. S., Smith T. J., Blieden T. M., Phipps R. P., Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation. The American Journal of Pathology 1997 151 2 317 322 2-s2.0-0031201054
7. Marshall R. P., Webb S., Bellingan G. J., Montgomery H. E., Chaudhari B., McAnulty R. J., Humphries S. E., Hill M. R., Laurent G. J., Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. The American Journal of Respiratory and Critical Care Medicine 2002 166 5 646 650 2-s2.0-0036724329 10.1164/rccm.2108086 (Pubitemid 34971844)
8. Marshall R. P., Bellingan G., Webb S., Puddicombe A., Goldsack N., McAnulty R. J., Laurent G. J., Fibroproliferation occurs early in the acute respiratory distress syndrome and impacts on outcome. The American Journal of Respiratory and Critical Care Medicine 2000 162 5 1783 1788 2-s2.0-0033679132
9. Serhan C. N., Brain S. D., Buckley C. D., Gilroy D. W., Haslett C., O'Neill L. A. J., Perretti M., Rossi A. G., Wallace J. L., Resolution of inflammation: state of the art, definitions and terms. FASEB Journal 2007 21 2 325 332 2-s2.0-33846823024 10.1096/fj.06-7227rev (Pubitemid 46213480)
10. Andersson-Sjoland A., Nihlberg K., Eriksson L., Bjermer L., Westergren-Thorsson G., Fibrocytes and the tissue niche in lung repair. Respiratory Research 2011 12 article 76 2-s2.0-79958055758 10.1186/1465-9921-12- 76
11. 1 inhibit interstitial fibrosis in the obstructed kidney via inhibition of local fibroblast proliferation. Journal of Pathology 2012 228 506 519
12. Ware L. B., Matthay M. A., The acute respiratory distress syndrome. The New England Journal of Medicine 2000 342 18 1334 1349 2-s2.0-0034604129 10.1056/NEJM200005043421806 (Pubitemid 30408719)
13. Botting R., Ayoub S. S., COX-3 and the mechanism of action of para-cetamol/acetaminophen. Prostaglandins, Leukotrienes and Essential Fatty Acids 2005 72 2 85 87 10.1016/j.plefa.2004.10.005 (Pubitemid 40051224)
14. Wu C. Y., Chi P. L., Hsieh H. L., Luo S. F., Yang C. M., TLR4-dependent induction of vascular adhesion molecule-1 in rheumatoid arthritis synovial fibroblasts: roles of cytosolic phospholipase a 2 /cyclooxygenase-2. Journal of Cellular Physiology 2010 223 2 480 491 2-s2.0-77950799883 10.1002/jcp.22059
15. 2 (PCPP) axis in inflammostasis. Inflammation Research 2011 60 12 1083 1092 2-s2.0-84855245938 10.1007/s00011-011-0385-7
16. 2 is specifically up-regulated in individuals in long-term remission from ulcerative colitis. Proceedings of the National Academy of Sciences of the United States of America 2010 107 26 12023 12027 2-s2.0-77955387223 10.1073/pnas.1004982107
17. Serhan C. N., Hong S., Gronert K., Colgan S. P., Devchand P. R., Mirick G., Moussignac R. L., Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. Journal of Experimental Medicine 2002 196 8 1025 1037 2-s2.0-0037152160 10.1084/jem.20020760 (Pubitemid 35231761)
18. Krishnamoorthy S., Recchiuti A., Chiang N., Yacoubian S., Lee C., Yang R., Petasis N. A., Serhan C. N., Resolvin D1 binds human phagocytes with evidence for proresolving receptors. Proceedings of the National Academy of Sciences of the United States of America 2010 107 4 1660 1665 2-s2.0-76549124239 10.1073/pnas.0907342107
19. Norling L. V., Dalli J., Flower R. J., Serhan C. N., Perretti M., Resolvin D1 limits polymorphonuclear leukocytes recruitment to inflammatory loci: receptor-dependent actions. Arteriosclerosis, Thrombosis, and Vascular Biology 2012 32 8 1970 1978 2-s2.0-84859524046 10.1161/ATVBAHA.112.249508
20. Sun Y. P., Oh S. F., Uddin J., Yang R., Gotlinger K., Campbell E., Colgan S. P., Petasis N. A., Serhan C. N., Resolvin D1 and its aspirin-triggered 17R epimer: stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation. The Journal of Biological Chemistry 2007 282 13 9323 9334 2-s2.0-34248233132 10.1074/jbc.M609212200 (Pubitemid 47104612)
21. Duffield J. S., Hong S., Vaidya V. S., Lu Y., Fredman G., Serhan C. N., Bonventre J. V., Resolvin D series and protectin D1 mitigate acute kidney injury. Journal of Immunology 2006 177 9 5902 5911 2-s2.0-33745621719 (Pubitemid 44628803)
22. Recchiuti A., Krishnamoorthy S., Fredman G., Chiang N., Serhan C. N., MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits. FASEB Journal 2011 25 2 544 560 2-s2.0-79551625082 10.1096/fj.10-169599
23. Tian H., Lu Y., Sherwood A. M., Hongqian D., Hong S., Resolvins el and dl in choroid-retinal endothelial cells and leukocytes: biosynthesis and mechanisms of anti-inflammatory actions. Investigative Ophthalmology and Visual Science 2009 50 8 3613 3620 2-s2.0-68349113741 10.1167/iovs.08-3146
24. Kasuga K., Yang R., Porter T. F., Agrawal N., Petasis N. A., Irimia D., Toner M., Serhan C. N., Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. Journal of Immunology 2008 181 12 8677 8687 2-s2.0-58849111789
25. Wang B., Gong X., Wan J., Zhang L., Zhang Z., Li H., Min S., Resolvin D1 protects mice from LPS-induced acute lung injury. Pulmonary Pharmacology and Therapeutics 2011 24 4 434 441 2-s2.0-79956160340 10.1016/j.pupt.2011.04.001
26. Fukunaga K., Kohli P., Bonnans C., Fredenburgh L. E., Levy B. D., Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury. Journal of Immunology 2005 174 8 5033 5039 2-s2.0-17044377563
27. Bonnans C., Fukunaga K., Levy M. A., Levy B. D., Lipoxin A4 regulates bronchial epithelial cell responses to acid injury. The American Journal of Pathology 2006 168 4 1064 1072 2-s2.0-33645459968 10.2353/ajpath.2006.051056
28. Bonner J. C., Rice A. B., Ingram J. L., Moomaw C. R., Nyska A., Bradbury A., Sessoms A. R., Chulada P. C., Morgan D. L., Zeldin D. C., Langenbach R., Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis. The American Journal of Pathology 2002 161 2 459 470 2-s2.0-0036965875 (Pubitemid 36142155)
29. Meade E. A., Smith W. L., DeWitt D. L., Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. The Journal of Biological Chemistry 1993 268 9 6610 6614 2-s2.0-0027480087 (Pubitemid 23099364)
30. Tong X. M., Wang J. C., Shen Y., Xie J., Zhang J. J., Jin J. Y., Inhibition of inflammatory mediators and related signaling pathways by macrophage-stimulating protein in rheumatoid arthritis synovial fibroblasts. Inflammation Research 2011 60 9 823 829 2-s2.0-80052043181 10.1007/s00011-011- 0338-1
31. Li X., Tupper J. C., Bannerman D. D., Winn R. K., Rhodes C. J., Harlan J. M., Phosphoinositide 3 kinase mediates toll-like receptor 4-induced activation of NF- B in endothelial cells. Infection and Immunity 2003 71 8 4414 4420 2-s2.0-0043267638 10.1128/IAI.71.8.4414-4420.2003 (Pubitemid 36919907)
32. Sznajder J. I., Alveolar edema must be cleared for the acute respiratory distress syndrome patient to survive. The American Journal of Respiratory and Critical Care Medicine 2001 163 6 1293 1294 2-s2.0-0034992884 (Pubitemid 32506584)
33. Perkins G. D., McAuley D. F., Thickett D. R., Gao F., The β -agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial. The American Journal of Respiratory and Critical Care Medicine 2006 173 3 281 287 2-s2.0-32144437063 10.1164/rccm.200508-1302OC (Pubitemid 43209082)
34. Smith F. G., Perkins G. D., Gates S., Young D., McAuley D. F., Tunnicliffe W., Khan Z., Lamb S. E., Effect of intravenous β -2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial. The Lancet 2012 379 9812 229 235 2-s2.0-84856102590 10.1016/S0140-6736(11)61623-1
35. Spite M., Summers L., Porter T. F., Srivastava S., Bhatnagar A., Serhan C. N., Resolvin D1 controls inflammation initiated by glutathione-lipid conjugates formed during oxidative stress. The British Journal of Pharmacology 2009 158 4 1062 1073 2-s2.0-70149123025 10.1111/j.1476-5381.2009.00234.x
36. Hudert C. A., Weylandt K. H., Lu Y., Serhan C. N., Wang J., Hong S., Dignass A., Kang J. X., Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis. Proceedings of the National Academy of Sciences of the United States of America 2006 103 30 11276 11281 2-s2.0-33746625086 10.1073/pnas.0601280103 (Pubitemid 44156509)
37. Gadek J. E., DeMichele S. J., Karlstad M. D., Pacht E. R., Donahoe M., Albertson T. E., Van Hoozen C., Wennberg A. K., Nelson J. L., Noursalehi M., Enteral nutrition with eicosapentaenoic acid (EPA), γ -linolenic acid (GLA) and antioxidants reduces pulmonary inflammation and new organ failures in patients with acute respiratory distress syndrome. Enteral nutrition in ARDS study group. Critical Care Medicine 1999 27 8 1409 1420
38. Quesnel C., Nardelli L., Piednoir P., Leçon V., Marchal-Somme J., Lasocki S., Bouadma L., Philip I., Soler P., Crestani B., Dehoux M., Alveolar fibroblasts in acute lung injury: biological behaviour and clinical relevance. European Respiratory Journal 2010 35 6 1312 1321 2-s2.0-77953491239 10.1183/09031936.00074709
39. Gilroy D. W., Colville-Nash P. R., Willis D., Chivers J., Paul-Clark M. J., Willoughby D. A., Inducible cyclooxygenase may have anti-inflammatory properties. Nature Medicine 1999 5 6 698 701 2-s2.0-0033000906 10.1038/9550 (Pubitemid 29289435)
40. Meade E. A., Smith W. L., DeWitt D. L., Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. The Journal of Biological Chemistry 1993 268 9 6610 6614 2-s2.0-0027480087 (Pubitemid 23099364)
41. Rajakariar R., Yaqoob M. M., Gilroy D. W., COX-2 in inflammation and resolution. Molecular Interventions 2006 6 4 199 207 2-s2.0-33749036034 10.1124/mi.6.4.6 (Pubitemid 44455202)
42. Morham S. G., Langenbach R., Loftin C. D., Tiano H. F., Vouloumanos N., Jennette J. C., Mahler J. F., Kluckman K. O., Ledford A., Lee C. A., Smithies O., Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 1995 83 3 473 482 2-s2.0-0028807498
43. Dai J. N., Zong Y., Zhong L. M., Li Y., Zhang W., Bian L., Ai Q., Liu Y., Sun J., Lu D., Gastrodin inhibits expression of inducible no synthase, cyclooxygenase-2 and proinflammatory cytokines in cultured LPS-Stimulated microglia via MAPK pathways. PLoS ONE 2011 6 7 2-s2.0-79960170945 10.1371/journal.pone.0021891 e21891
44. Frazier W. J., Wang X., Wancket L. M., Li X. A., Meng X., Nelin L. D., Cato A. C. B., Liu Y., Increased inflammation, impaired bacterial clearance, and metabolic disruption after gram-negative sepsis in Mkp-1-deficient mice. Journal of Immunology 2009 183 11 7411 7419 2-s2.0-73349120613 10.4049/jimmunol.0804343
45. Zhang W. J., Wei H., Hagen T., Frei B., -lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway. Proceedings of the National Academy of Sciences of the United States of America 2007 104 10 4077 4082 2-s2.0-34247220265 10.1073/pnas.0700305104 (Pubitemid 47181581)
46. Xu C. Q., Liu B. J., Wu J. F., Xu Y., Duan X., Cao Y., Dong J., Icariin attenuates LPS-induced acute inflammatory responses: involvement of PI3K/Akt and NF B signaling pathway. European Journal of Pharmacology 2010 642 1-3 146 153 2-s2.0-77954624419 10.1016/j.ejphar.2010.05.012
47. Mebratu Y., Tesfaigzi Y., How ERK1/2 activation controls cell proliferation and cell death is subcellular localization the answer? Cell Cycle 2009 8 8 1168 1175 2-s2.0-65949119310
48. Vantaggiato C., Formentini I., Bondanza A., Bonini C., Naldini L., Brambilla R., ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially. Journal of Biology 2006 5 article 14 2-s2.0-33845904217 10.1186/jbiol38