Energy dependence of HCD on peptide fragmentation: Stepped collisional energy finds the sweet spot

Journal of the American Society for Mass Spectrometry

Volumn 24, Issue 11, 2013, Pages 1690-1699

  Diedrich, Jolene K ^a   Pinto, Antonio F M ^b   Yates III, John R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MINISTRY OF EDUCATION OF BRAZIL   (Brazil)

Author keywords

d Ions; Immonium ion; Leucine and isoleucine differentiation; Phosphorylation; Q Exactive; Stepped collision energy; TMT

Indexed keywords

COLLISION ENERGIES; COLLISIONAL DISSOCIATION; COLLISIONAL ENERGIES; PEPTIDE FRAGMENTATION; PEPTIDE IDENTIFICATION; PROTEIN IDENTIFICATION; Q EXACTIVE; TMT;

AMINO ACIDS; IONS; MOLECULAR BIOLOGY; PHOSPHORYLATION;

PEPTIDES;

GLUTAMYLLEUCYLGLYCYLGLUTAMINYLALANYLGLYCYLVALYLASPARTYLTHREONYLTYROSYLLEUCYLGLUTAMINYLTHREONYLLYSINE; GLYCYLISOLEUCYLLEUCYLPHENYLALANYLVALYLGLYCYLSERYLGLYCYLVALYLSERYLGLYCYLGLYCYLGLUATMYLGLUTAMYLGLYCYLALANYLARGININE; LEUCYLTHREONYLISOLEUCYLLEUCYLGLUTAMYLGLUTAMYLLEUCYLARGININE; PHOSPHOPEPTIDE; THREONYLARGINYLASPARTYLISOLEUCYLTYROSYLGLUTAMYLTHREONYLASPARTYLPHOSPHOTYROSINETYROSYLARGINYLLYSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL ACTIVATION; CELL LYSATE; CHEMICAL LABELING; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; ENERGY; FRAGMENTATION REACTION; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEOMICS; QUANTITATIVE ANALYSIS; TANDEM MASS TAG QUANTITATION;

AMINO ACID SEQUENCE; BRONCHI; CHROMATOGRAPHY, LIQUID; CYSTIC FIBROSIS; EPITHELIAL CELLS; HEK293 CELLS; HUMANS; PEPTIDE FRAGMENTS; PEPTIDES; PHOSPHORYLATION; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84885645216     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-013-0709-7     Document Type: Article

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