Activation markers of peripheral blood mononuclear cells in late pregnancy and after delivery: A pilot study

Annals of the Rheumatic Diseases

Volumn 64, Issue 2, 2005, Pages 318-320

  Ostensen M ^a   Sicher, P ^a   Forger F ^a   Villiger, P M ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CXCR3; HLA DR ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; NONSTEROID ANTIINFLAMMATORY AGENT; SALAZOSULFAPYRIDINE;

ARTICLE; BLOOD SAMPLING; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNE RESPONSE; PERINATAL PERIOD; PERIPHERAL BLOOD MONONUCLEAR CELL; PILOT STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL; THIRD TRIMESTER PREGNANCY;

ADULT; ARTHRITIS, RHEUMATOID; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNITY, CELLULAR; LYMPHOCYTE ACTIVATION; PILOT PROJECTS; POSTPARTUM PERIOD; PREGNANCY; PREGNANCY COMPLICATIONS; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TH2 CELLS;

EID: 13244294176     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2004.022558     Document Type: Article

References (13)

1. Wegmon TG, Lin H, Guilbert L, Mossmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon? Immunol Today 1993;14:353-6.
2. Østensen M, Fuhrer L, Mathieu R, Seitz M, Villiger PM. A prospective study of pregnant patients with rheumatoid arthritis and ankylosing spondylitis using validated instruments. Ann Rheum Dis 2004;63:1212-17.
3. Mosmann TR, Sad S. The expanding universe of T cell subsets TH1, TH2 and more. Immunol Today 1996;17:138-40.
4. Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998;187:875-83.
5. Ruth JH, Rottman JB, Katschke KJ, Qin S, Wu L, LaRosa G, et al. Selective lymphocyte chemokine receptor expression in the rheumatoid joint. Arthritis Rheum 2001;44:2750-60.
6. Wedderburn LR, Robinson N, Patel A, Varsani H, Woo P. Selective recruitment of polarized T cells expressing CCR5 and CXCR3 to the inflamed joints of children with juvenile idiopathic arthritis. Arthritis Rheum 2000;43:765-74.
7. Elenkov U, Wilder RL, Bakalov VK, Link AA, Dimitrov MA, Fisher S, et al. IL-12, TNF-alpha, and hormonal changes during late pregnancy and early postpartum: implications for autoimmune disease activity during these times. J Clin Endocrinol Metab 2001;86:4933-8.
8. Tsuda H, Michimata T, Hayakawa S, Tanebe K, Saqkai M, Fujimura M, et al. A Th2 chemokine, TARC, produced by trophoblasts and endometrial gland cells, regulates the infiltration of CCR4+ T lymphocytes into human deciduas at early pregnancy. Am J Reprod Immunol 2002;48:1-8.
9. Munoz-Valle JF, Vazquez-Del Mercado M, Garcia-Iglesias T, Orozco-Barocio G, Bernard-Medina G, et al. T(H)1/T(H)2 cytokine profile, metallopratease-9 activity and hormonal status in pregnant rheumatoid arthritis and systemic lupus erytrtematosus patients. Clin Exp Immunol 2003;131:377-84.
10. Matthiesen L, Berg G, Ernerudh J, Hakansson L. Lymphocyte subsets and mitogen stimulation of blood lymphocytes in normal pregnancy. Am J Reprod Immunol 1996;35:70-9.
11. Kühnert M, Strohmeier R, Stegmüller M, Halberstadt E. Changes in lymphocyte subsets during normal pregnancy. Eur J Obstet Gynecol 1998;76:147-51.
12. Mahmoud F, Abul H, Omu A, Al-Rayes S, Haines D, Whaley K. Pregnancy-associated changes in peripheral blood lymphocyte subpopulations in normal Kuwaiti women. Gynecol Obstet Invest 2001;52:232-6.
13. Kuhnert M, Schmidt S. Changes in lymphocyte subsets during pregnancy and post-partum in cases of beginning eclampsia. J Perinat Med 2000;28:389-98.