Ubiquitin E3 ligase CRL4CDT2/DCAF2 as a potential chemotherapeutic target for ovarian surface epithelial cancer

Journal of Biological Chemistry

Volumn 288, Issue 41, 2013, Pages 29680-29691

  Pan, Wei Wei ^a,b,d   Zhou, Jian Jie ^c   Yu, Chao ^a   Xu, Ying ^d   Guo, Lian Jun ^d   Zhang, Hai Yi ^a   Zhou, Dawang ^c   Song, Fang Zhou ^b   Fan, Heng Yu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c XIAMEN UNIVERSITY   (China)

^d JIAXING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-CANCER AGENTS; APOPTOSIS INDUCTION; CHEMOTHERAPEUTIC DRUGS; DOSE-DEPENDENT MANNER; OVARIAN CANCER CELLS; PHARMACOLOGICAL EFFECTS; POTENTIAL DRUG TARGETS; TUMOR SUPPRESSION;

CELL DEATH; CHEMICAL ACTIVATION; ENZYMES; HISTOLOGY; TUMORS;

DISEASES;

CULLIN RING UBIQUITIN LIGASE 4; PEVONEDISTAT; REPLICATION LICENSING FACTOR CDT1; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; CANCER CELL; CANCER CHEMOTHERAPY; CELL CYCLE ARREST; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; DRUG TARGETING; ENZYME SUBSTRATE; EPITHELIUM; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; HUMAN TISSUE; OVARY CANCER; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; TISSUE DISTRIBUTION;

APOPTOSIS; CANCER THERAPY; CDT2; DNA DAMAGE; E3 UBIQUITIN LIGASE; MLN4924; OVARIAN CANCER;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLOPENTANES; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, NUDE; NEOPLASMS, GLANDULAR AND EPITHELIAL; NUCLEAR PROTEINS; OVARIAN NEOPLASMS; PYRIMIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UBIQUITIN-PROTEIN LIGASES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84885609279     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.495069     Document Type: Article

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