Heat shock protein 70 (HSP70) expression is associated with poor prognosis in intestinal type gastric cancer

Virchows Archiv

Volumn 463, Issue 4, 2013, Pages 489-495

  Lee, Hyoun Wook ^a   Lee, Eun Hee ^a   Kim, Seok Hyun ^a   Roh, Mee Sook ^b   Jung, Sang Bong ^c   Choi, Young Cheol ^a  

^a Sungkyunkwan University   (South Korea)

^b Dong A University   (South Korea)

^c Gimhae College University   (South Korea)

Author keywords

Gastric cancer; HSP70; Immunohistochemistry; Intestinal type; Prognosis

Indexed keywords

HEAT SHOCK PROTEIN 70;

ARTICLE; CANCER CELL; CANCER CLASSIFICATION; CANCER GROWTH; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; STOMACH CANCER; TISSUE MICROARRAY;

ADENOCARCINOMA; ADULT; AGED; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; STOMACH NEOPLASMS; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84885575140     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-013-1461-x     Document Type: Article

References (34)

1. Howson CP, Hiyama T, Wynder EL (1986) The decline of gastric cancer: epidemiology of an unplanned triumph. Epidemiol Rev 8:1-27
2. Akoh JA, Macintyre IM (1992) Improving survival in gastric cancer: review of 5-year survival rates in English language publications from 1970. Br J Surg 79:293-299
3. Hundahl SA, Menck HR, Mansour EG, Winchester DP (1997) The National Cancer Data Base report on gastric carcinoma. Cancer 80:2333-2341
4. Tabernero J, Macarulla T, Ramos FJ, Baselga J (2005) Novel targeted therapies in the treatment of gastric and esophageal cancer. Ann Oncol 16:1740-1748
5. Lee W, Patel JH, Lockhart AC (2009) Novel targets in esophageal and gastric cancer: beyond antiangiogenesis. Expert Opin Investig Drugs 18:1351-1364
6. Neckers L, Workman P (2012) Hsp90 molecular chaperone inhibitors: are we there yet? Clin Cancer Res 18:64-76
7. Goloudina AR, Demidov ON, Garrido C (2012) Inhibition of HSP70: a challenging anti-cancer strategy. Cancer Lett 325:117-124
8. Schlesinger MJ (1990) Heat shock proteins. J Biol Chem 265:12111-12114
9. Hendrick JP, Hartl FU (1993) Molecular chaperone functions of heat-shock proteins. Annu Rev Biochem 62:349-384
10. Hartl FU (1996) Molecular chaperones in cellular protein folding. Nature 381:571-579
11. Lindquist S, Craig EA (1988) The heat-shock proteins. Annu Rev Genet 22:631-677
12. Calderwood SK, Khaleque MA, Sawyer DB, Ciocca DR (2006) Heat shock proteins in cancer: chaperones of tumorigenesis. Trends Biochem Sci 31:164-172
13. Khalil AA, Kabapy NF, Deraz SF, Smith C (2011) Heat shock proteins in oncology: diagnostic biomarkers or therapeutic targets? Biochim Biophys Acta 1816:89-104
14. Lazaris AC, Chatzigianni EB, Panoussopoulos D, Tzimas GN, Davaris PS, Golematis BC (1997) Proliferating cell nuclear antigen and heat shock protein 70 immunolocalization in invasive ductal breast cancer not otherwise specified. Breast Cancer Res Treat 43:43-51
15. Bauer K, Nitsche U, Slotta-Huspenina J, Drecoll E, von Weyhern CH, Rosenberg R, Höfler H, Langer R (2012) High HSP27 and HSP70 expression levels are independent adverse prognostic factors in primary resected colon cancer. Cell Oncol 35:197-205
16. Santarosa M, Favaro D, Quaia M, Galligioni E (1997) Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients. Eur J Cancer 33:873-877
17. Tavassol F, Starke OF, Kokemüller H, Wegener G, Müller-Tavassol CC, Gellrich NC, Eckardt A (2011) Prognostic significance of heat shock protein 70 (HSP70) in patients with oral cancer. Head Neck Oncol 3:10
18. Maehara Y, Oki E, Abe T, Tokunaga E, Shibahara K, Kakeji Y, Sugimachi K (2000) Overexpression of the heat shock protein HSP70 family and p53 protein and prognosis for patients with gastric cancer. Oncology 58:144-151
19. Canöz O, Belenli O, Patiroglu TE (2002) General features of gastric carcinomas and comparison of HSP70 and NK cell immunoreactivity with prognostic factors. Pathol Oncol Res 8:262-269
20. Isomoto H, Oka M, Yano Y, Kanazawa Y, Soda H, Terada R, Yasutake T, Nakayama T, Shikuwa S, Takeshima F, Udono H, Murata I, Ohtsuka K, Kohno S (2003) Expression of heat shock protein (Hsp) 70 and Hsp 40 in gastric cancer. Cancer Lett 198:219-228
21. Lauren PA, Nevalainen TJ (1993) Epidemiology of intestinal and diffuse types of gastric carcinoma. Cancer 71:2926-2933
22. Komoto K, Haruma K, Kamada T, Tanaka S, Yoshihara M, Sumii K, Kajiyama G, Talley NJ (1998) Helicobacter pylori infection and gastric neoplasia: correlations with histological gastritis and tumor histology. Am J Gastroenterol 93:1271-1276
23. Ohata H, Kitauchi S, Yoshimura N, Mugitani K, Iwane M, Nakamura H, Yoshikawa A, Yanaoka K, Arii K, Tamai H, Shimizu Y, Takeshita T, Mohara O, Ichinose M (2004) Progression of chronic atrophic gastritis associated with Helicobacter pylori infection increases risk of gastric cancer. Int J Cancer 109:138-143
24. Grabiec J, Owen DA (1985) Carcinoma of the stomach in young persons. Cancer 56:388-390
25. Zanghieri G, Di Gregorio C, Sacchetti C, Fante R, Sassatelli R, Cannizzo G, Carriero A, Ponz de Leon M (1990) Familial occurrence of gastric cancer in the 2-years experience of a population-based registry. Cancer 66:2047-2051
26. Dunbier A, Guilford P (2001) Hereditary diffuse gastric cancer. Adv Cancer Res 83:55-65
27. Washington K (2010) 7th edition of the AJCC cancer staging manual: stomach. Ann Surg Oncol 17:3077-3079
28. Targosz A, Brzozowski T, Pierzchalski P, Szczyrk U, Ptak-Belowska A, Konturek SJ, Pawlik W (2012) Helicobacter pylori promotes apoptosis, activates cyclooxygenase (COX)-2 and inhibits heat shock protein HSP70 in gastric cancer epithelial cells. Inflamm Res 61:955-966
29. Axsen WS, Styer CM, Solnick JV (2009) Inhibition of heat shock protein expression by Helicobacter pylori. Microb Pathog 47:231-236
30. Targosz A, Pierzchalski P, Krawiec A, Szczyrk U, Brzozowski T, Konturek SJ, Pawlik WW (2006) Helicobacter pylori inhibits expression of heat shock protein 70 (HSP70) in human epithelial cell line. Importance of Cag A protein. J Physiol Pharmacol 57:265-278
31. Tokunaga Y, Shirahase H, Hoppou T, Kitaoka A, Tokuka A, Ohsumi K (2000) Density of Helicobacter pylori infection evaluated semiquantitatively in gastric cancer. J Clin Gastroenterol 31:217-221
32. Marunouchi T, Hosoya H (1993) Regulation of hsc70 expression in the human histiocytic lymphoma cell line, U937. Cell Struct Funct 18:437-447
33. Lazaris AC, Theodoropoulos GE, Davaris PS, Panoussopoulos D, Nakopoulou L, Kittas C, Golemantis BC (1995) Heat shock protein 70 and HLA-DR molecules tissue expression. Dis Colon Rectum 38:739-745
34. Sugerman PB, Savage NW, Xu LJ, Walsh LJ, Seymour GJ (1995) Heat shock protein expression in oral epithelial dysplasia and squamous cell carcinoma. Eur J Cancer B Oral Oncol 31B:63-67