Overexpression of the heat shock protein HSP70 family and p53 protein and prognosis for patients with gastric cancer

Oncology

Volumn 58, Issue 2, 2000, Pages 144-151

  Maehara, Yoshihiko ^a,b   Oki, Eiji ^a   Abe, Toru ^b   Tokunaga, Eriko ^a   Shibahara, Kotaro ^b   Kakeji, Yoshihiro ^b   Sugimachi, Keizo ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Gastric cancer; Heat shock protein; p53; Prognosis

Indexed keywords

HEAT SHOCK PROTEIN; PROTEIN P53;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DIAGNOSTIC VALUE; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; STOMACH CANCER; STRESS;

EID: 0033994048     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000012091     Document Type: Article

References (42)

1. Morimoto RI: Heat shock: The role of transient inducible responses in cell damage, transformation, and differentiation. Cancer Cells 1991; 3:295-301.
2. Ellis RJ: The molecular chaperone concept. Semin Cell Biol 1990;1:1-9.
3. Kost SL, Smith DF, Sullivan WP, Welch WJ, Toft DO: Binding of heat shock proteins to the avian progesterone receptor. Mol Cell Biol 1989;9:3829-3838.
4. Pinhasi-Kimhi O, Michalovitz D, Ben-Zeev A, Oren M: Specific interaction between the p53 cellular tumour antigen and major heat shock proteins. Nature 1986;320:182-184.
5. Hinds PW, Finlay CA, Frey AB, Levine AJ: Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines. Mol Cell Biol 1987;7:2863-2869.
6. Finlay CA, Hinds PW, Tan T-H, Eliyahu TD, Oren M, Levine AJ: Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 1988;8:531-539.
7. r 73,000 heat shock cognate protein. Cancer Res 1993;53:1702-1705.
8. Margulis BA, Welsh M: Analysis of protein binding to heat shock protein 70 in pancreatic islet cells exposed to elevated temperatures or interleukin 1β. J Biol Chem 1991;266:9295-9298.
9. Koskinen PJ, Sisitonen L, Evan G, Morimoto R, Alitalo K: Nuclear colocalization of cellular and viral myc proteins with HSP70 in myc-overexpressing cells. J Virol 1991;65:842-851.
10. Abd El All H, Rey A, Duvillard P: Expression of heat shock protein 70 and c-myc in cervical carcinoma. Anticancer Res 1998;18:1533-1536.
11. Walter G, Carbone A, Welch WJ: Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein. J Virol 1987; 61:405-410.
12. Welch WJ, Feramisco JR: Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells. J Biol Chem 1984;259:4501-4513.
13. r of 63,000, 56,000, and 50,000. J Biol Chem 1991; 266:6708-6713.
14. Harris CC, Hollstein M: Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 1993;329:1318-1327.
15. Gannon JV, Greaves R, Iggo R, Lane DP: Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J 1990;9: 1595-1602.
16. Levine AJ, Momand J, Finlay CA: The p53 tumour suppressor gene. Nature 1991;351: 453-456.
17. Velazquez JM, Lindquist S: hsp70: Nuclear concentration during environmental stress and cytoplasmic storage during recovery. Cell 1984; 36:655-662.
18. Li GC, Li L, Liu Y-K, Mak JY, Chen LL, Lee WM: Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding gene. Proc Natl Acad Sci USA 1991;88:1681-1685.
19. Ciocca DR, Fuqua SAW, Lock-Lim S, Toft DO, Welch WJ, McGuire WL: Response of human breast cancer cells to heat shock and chemotherapeutic drugs. Cancer Res 1992;52: 3648-3654.
20. Ciocca DR, Clark GM, Tandon AK, Fuqua SAW, Welch WJ, McGuire WL: Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: Prognostic implications. J Natl Cancer Inst 1993;85:570-574.
21. Jäättelä M: Over-expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells. Int J Cancer 1995;60:689-693.
22. Bozzetti F, Bonfanti G, Bufalino R, Menotti V, Persano S, Andreola S, Doci R, Gennari L: Adequacy of margins of resection in gastrectomy for cancer. Ann Surg 1982;196:685-690.
23. Maehara Y, OkuyamaT, Moriguchi S, Orita H, Kusumoto H, Korenaga D, Sugimachi K: Prophylactic lymph node dissection in patients with advanced gastric cancer promotes increased survival time. Cancer 1992;70:392-395.
24. Korenaga D, Okamura T, Baba H, Saito A, Sugimachi K: Results of resection of gastric cancer extending to adjacent organs. Br J Surg 1988;75:12-15.
25. Japanese Research Society for Gastric Cancer: The general rules for the gastric cancer study in surgery and pathology. Part I. Clinical classification. Jpn J Surg 1981;11:127-139. Part II. Histological classification of gastric cancer. Jpn J Surg 1981;11:140-145.
26. Japanese Research Society for Gastric Cancer: The general rules for the gastric cancer study in surgery and pathology. Part I. Clinical classification. Jpn J Surg 1981;11:127-139. Part II. Histological classification of gastric cancer. Jpn J Surg 1981;11:140-145.
27. Japanese Research Society for Gastric Cancer: The General Rules for Gastric Cancer Study, ed 12 (in Japanese). Tokyo, Kanehara, 1993.
28. Elledge RM, Clark GM, Fuqua SAW, Yu YY, Allred DC: p53 protein accumulation detected by five different antibodies: Relationship to prognosis and heat shock protein 70 in breast cancer. Cancer Res 1994;54:3752-3757.
29. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
30. Dixon WJ (ed): BMDP Statistical Software. Berkeley, University of California Press, 1988.
31. Kakeji Y, Korenaga D, Tsujitani S, Baba H, Anai H, Maehara Y, Sugimachi K: Gastric cancer with p53 overexpression has high potential for metastasising to lymph nodes. Br J Cancer 1993;67:589-593.
32. Multihoff G, Botzler C, Wiesnet M, Müller E, Meier T, Wilmanns W, Issels RD: A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells. Int J Cancer 1995;61:272-279.
33. Blachere NE, Srivastave PK: Heat shock protein-based cancer vaccines and related thoughts on immunogenicity of human tumors. Cancer Biol 1995;6:349-355.
34. Heike M, Noll B, Meyer zum Büschenfelde KH: Heat shock protein-peptide complexes for use in vaccines. J Leukoc Biol 1996;60:153-158.
35. Randell Brown C, Martin RL, Hansen WJ, Beckmann RP, Welch WJ: The constitutive and stress inducible forms of hsp 70 exhibit functional similarities and interact with one another in an ATP-dependent fashion. J Cell Biol 1993;120:1101-1112.
36. Ehrhart JC, Duthu A, Ullrich S, Appella E, May P: Specific interaction between a subset of the p53 protein family and heat shock protein hsp72/hsc73 in a human osteosarcoma cell line. Oncogene 1988;3:595-603.
37. Lazaris AC, Theodoropoulos GE, Davaris PS, Panoussopoulos D, Nakopoulou L, Kittas C, Golemantis BC: Heat shock protein 70 and HLA-DR molecules tissue expression. Dis Colon Rectum 1995;38:739-745.
38. Sugerman PB, Savage NW, Xu U, Walsh LJ, Seymour GJ: Heat shock protein expression in oral epithelial dysplasia and squamous cell carcinoma. Eur J Cancer B Oral Oncol 1995;31B: 63-67.
39. Marunouchi T, Hosoya H: Regulation of hsc70 expression in the human histiocytic lymphoma cell line, U937. Cell Struct Funct 1993;18:437-447.
40. Twomey BM, McCallum S, Isenberg DA, Latchman DS: Elevation of heat shock protein synthesis and hsp gene transcription during monocyte to macrophage differentiation of U937 cells. Clin Exp Immunol 1993;93:178-183.
41. Lee CS, Montebello J, Rush M, Georgiou T, Wawryk S, Rode J: Overexpression of heat shock protein (hsp) 70 associated with abnormal p53 expression in cancer of the pancreas. Zentralbl Pathol 1994;140:259-264.
42. Takahashi M, Mikami T, Watanabe Y, Okazaki M, Okazaki Y, Okazaki A, Sato T, Asaishi K, Hirata K, Narimatsu E, Mori M, Sato N, Kikuchi K: Correlation of heat shock protein 70 expression with estrogen receptor levels in invasive human breast cancer. Am J Clin Pathol 1994;101:519-525.