Structural and biochemical characterization of the essential DsbA-like disulfide bond forming protein from Mycobacterium tuberculosis

BMC Structural Biology

Volumn 13, Issue 1, 2013, Pages

  Chim, Nicholas ^a   Harmston, Christine A ^a   Guzman, David J ^a   Goulding, Celia W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Disulfide bond; DsbA; Mycobacterium tuberculosis; Oxidoreductase; Vitamin K epoxide reductase; X ray crystallography

Indexed keywords

BACTERIAL PROTEIN; CYSTEINE; DSBA PROTEIN; DSBE PROTEIN; DSBF PROTEIN; ISOMERASE; THIOREDOXIN; UNCLASSIFIED DRUG; VKOR PROTEIN;

ALPHA HELIX; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; ENZYME ACTIVITY; HOST PATHOGEN INTERACTION; IN VITRO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION REDUCTION STATE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DISULFIDES; GENES, BACTERIAL; ISOMERASES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES; PROTEIN REFOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEOME; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; THIOREDOXINS;

EID: 84885496417     PISSN: None     EISSN: 14726807     Source Type: Journal    
DOI: 10.1186/1472-6807-13-23     Document Type: Article

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