PPAR-γ activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1

European Journal of Pharmacology

Volumn 715, Issue 1-3, 2013, Pages 196-203

  Hou, Xiaoyang ^a,b   Zhang, Ying ^d   Shen, Ying H ^b   Liu, Tongbao ^a   Song, Shangming ^a   Cui, Lianqun ^a   Bu, Peili ^c  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c SHANDONG UNIVERSITY   (China)

^d Department of Cardiology   (China)

Author keywords

Activator protein 1; Cardiac fibroblast; Differentiation; Peroxisome proliferator activated; Receptor

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ANGIOTENSIN II; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CYCLIN D1; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; FIBROSIS; G1 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSCRIPTION; IN VITRO STUDY; MYOFIBROBLAST; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C FOS; ONCOGENE C JUN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; RAT;

ACTIVATOR PROTEIN-1; CARDIAC FIBROBLAST; CYCLIN D(1); DIFFERENTIATION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-Γ;

ANGIOTENSIN II; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; COLLAGEN TYPE I; COLLAGEN TYPE III; CYCLIN D1; FIBROBLASTS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; MYOFIBROBLASTS; PHENOTYPE; PPAR GAMMA; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; RNA, MESSENGER; THIAZOLIDINEDIONES; TRANSCRIPTION FACTOR AP-1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84885485624     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.05.021     Document Type: Article

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