The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety

European Journal of Pharmacology

Volumn 715, Issue 1-3, 2013, Pages 105-110

  Grivas, Vasilios ^a   Markou, Athina ^b   Pitsikas, Nikolaos ^a  

^a UNIVERSITY OF THESSALY   (Greece)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anxiety; Light dark test; LY379268; Open field test; Rat

Indexed keywords

4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; GROOMING; LOCOMOTION; MALE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TRANQUILIZING ACTIVITY;

ANXIETY; LIGHT/DARK TEST; LY379268; MGLU(2/3) RECEPTOR; OPEN FIELD TEST; RAT;

AMINO ACIDS; ANIMALS; ANXIETY; BICYCLO COMPOUNDS, HETEROCYCLIC; DARKNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; LOCOMOTION; MALE; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 84885480473     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.05.048     Document Type: Article

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