Reduced sense of agency in chronic schizophrenia with predominant negative symptoms

Psychiatry Research

Volumn 209, Issue 3, 2013, Pages 386-392

  Maeda, Takaki ^a   Takahata, Keisuke ^a,c   Muramatsu, Taro ^a   Okimura, Tsukasa ^a   Koreki, Akihiro ^a   Iwashita, Satoru ^b   Mimura, Masaru ^a   Kato, Motoichiro ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Sakuragaoka Memorial Hospital   (Japan)

^c NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Dopamine; Glutamate; Optimal cue integration; Post diction; Prediction; Self disturbance; Sense of agency

Indexed keywords

ACTION LINKED EXPERIMENT; ADULT; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; EVENT PRIOR TO ACTION EXPERIMENT; FEMALE; GLOBAL ASSESSMENT OF FUNCTIONING; HUMAN; MALE; MENTAL TEST; NEGATIVE SYNDROME; OPTIMAL CUE INTEGRATION FRAMEWORK; PARANOID SCHIZOPHRENIA; POSITIVE AND NEGATIVE SYNDROME SCALE; POSITIVE SYNDROME; POSTDICTIVE PROCESS; PREDICTIVE PROCESS; PRIORITY JOURNAL; RESIDUAL SCHIZOPHRENIA; RESPONSE TIME; SELF CONTROL; SELF DISTURBANCE; SENSE OF AGENCY; SENSORIMOTOR INTEGRATION; TEMPORAL BIAS;

DOPAMINE; GLUTAMATE; OPTIMAL CUE INTEGRATION; POST-DICTION; PREDICTION; SELF-DISTURBANCE; SENSE OF AGENCY;

ADULT; ANALYSIS OF VARIANCE; CHRONIC DISEASE; FEMALE; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; REACTION TIME; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SENSATION DISORDERS; STATISTICS AS TOPIC; STATISTICS, NONPARAMETRIC;

EID: 84885468810     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2013.04.017     Document Type: Article

References (56)

1. Blakemore S.J. The perception of self-produced sensory stimuli in patients with auditory hallucinations and passivity experiences: evidence for a breakdown in self-monitoring. Psychological Medicine 2000, 30:1131-1139.
2. Blakemore S.J., Wolpert D.M., Frith C.D. Abnormalities in the awareness of action. Trends in Cognitive Sciences 2002, 6:237-242.
3. Carlsson A. The current status of the dopamine hypothesis of schizophrenia. Neuropsychopharmacology 1988, 1:179-186.
4. Carlsson A., Hansson L.O., Waters N., Carlsson M.L. A glutamatergic deficiency model of schizophrenia. British Journal of Psychiatry 1999, 174(Suppl. 37):2-6.
5. Corlett P.R., Honey G.D., Fletcher P.C. From prediction error to psychosis: ketamine as a pharmacological model of delusions. Journal of Psychopharmacology 2007, 21:238-252.
6. Corlett P.R., Frith C.D., Fletcher P.C. From drugs to deprivation: a Bayesian framework for understanding models of psychosis. Psychopharmacology (Berlin) 2009, 206:515-530.
7. Corlett P.R., Taylor J.R., Wang X.J., Fletcher P.C., Krystal J.H. Toward a neurobiology of delusions. Progress in Neurobiology 2010, 92:345-369.
8. Corlett P.R., Honey G.D., Krystal J.H., Fletcher P.C. Glutamatergic model psychoses: prediction error, learning, and inference. Neuropsychopharmacology 2011, 36:294-315.
9. Crow T.J. Molecular pathology of schizophrenia: more than one disease processes?. British Medical Journal 1980, 280:66-68.
10. Daprati E., Franck N., Georgieff N., Proust J., Pacherie E., Dalery J., Jeannerod M. Looking for the agent: an investigation into consciousness of action and self-consciousness in schizophrenic patients. Cognition 1997, 65:71-86.
11. Davis K.L., Kahn R.S., Ko G., Davidson M. Dopamine in schizophrenia: a review and reconceptualization. American Journal of Psychiatry 1991, 148:1474-1486.
12. Desantis A., Roussel C., Waszak F. On the influence of causal beliefs on the feeling of agency. Consciousness and Cognition 2011, 20:1011-1020.
13. Fletcher P.C., Frith C.D. Perceiving is believing: a Bayesian approach to explaining the positive symptoms of schizophrenia. Nature Reviews Neuroscience 2009, 10:48-58.
14. Franck N., Farrer C., Georgieff N., Marie-Cardine M., Daléry J., d'Amato T., Jeannerod M. Defective recognition of one's own actions in patients with schizophrenia. American Journal of Psychiatry 2001, 158:454-459.
15. Frith C.D., Blakemore S.J., Wolpert D.M. Explaining the symptoms of schizophrenia: abnormalities in the awareness of action. Brain Research Reviews 2000, 31:357-363.
16. Gallagher S. Philosophical conceptions of the self: implications for cognitive science. Trends in Cognitive Sciences 2000, 4:14-21.
17. Gallagher S. Neurocognitive models of schizophrenia: a neurophenomenological critique. Psychopathology 2004, 37:8-19.
18. Georgieff N., Jeannerod M. Beyond consciousness of external reality: a ''who'' system for consciousness of action and self-consciousness. Consciousness and Cognition 1998, 7:465-477.
19. Goff D.C., Coyle J.T. The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. American Journal of Psychiatry 2001, 158:1367-1377.
20. Gross G., Huber G., Klosterkotter J., Linz M. BSABS: Bonn Scale for the Assessment of Basic Symptoms (1st Complete English Edition) 2008, Shaker Verlag, Aachen.
21. Haggard P., Clark S., Kalogeras J. Voluntary action and conscious awareness. Nature Neuroscience 2002, 5:382-385.
22. Haggard P., Martin F., Taylor-Clarke M., Jeannerod M., Franck N. Awareness of action in schizophrenia. Neuroreport 2003, 14:1081-1085.
23. Haggard P. Conscious intention and motor cognition. Trends in Cognitive Sciences 2005, 9:290-295.
24. Haggard P. Conscious intention and the sense of agency. Disorders of Volition 2006, 175-192. MIT Press, Massachusetts. N. Sebanz, W. Prinz (Eds.).
25. Hauser M., Knoblich G., Repp B.H., Lautenschlager M., Gallinat J., Heinz A., Voss M. Altered sense of agency in schizophrenia and the putative psychotic prodrome. Psychiatry Research 2011, 186:170-176.
26. Hauser M., Moore J.W., de Millas W., Gallinat J., Heinz A., Haggard P., Voss M. Sense of agency is altered in patients with a putative psychotic prodrome. Schizophrenia Research 2011, 126:20-27.
27. Huber G. Das Konzept substratnaher Basissymptome und seine Bedeutung für Therie und Therapie schizophrener Erkrankungen. Nervenarzt 1983, 54:23-32.
28. Kapur S. Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. American Journal of Psychiatry 2003, 160:13-23.
29. Kay S.R. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin 2007, 13:261-276.
30. Libet B., Gleason C.A., Wright E.W., Pearl D.K. Time of conscious intention to act in relation to onset of cerebral activity (readiness-potential). The unconscious initiation of a freely voluntary act. Brain 1983, 106:623-642.
31. Lindner A., Their P., Kircher T.T., Haarmeier T., Leube D.T. Disorders of agency in schizophrenia correlate with an inability to compensate for the sensory consequences of actions. Current Biology 2005, 15:1119-1124.
32. Maeda T., Kato M., Muramatsu T., Iwashita S., Mimura M., Kashima H. Aberrant sense of agency in patients with schizophrenia: forward and backward over-attribution of temporal causality during intentional action. Psychiatry Research 2012, 198:1-6.
33. Moore J.W., Haggard P. Awareness of action: inference and prediction. Consciousness and Cognition 2008, 17:136-144.
34. Moore J.W., Wegner D.M., Haggard P. Modulating the sense of agency with external cues. Consciousness and Cognition 2009, 18:1056-1064.
35. Moore J.W., Schneider S.A., Schwingenschuh P., Moretto G., Bhatia K.P., Haggard P. Dopaminergic medication boosts action-effect binding in Parkinson's disease. Neuropsychologia 2010, 48:1125-1132.
36. Moore J.W., Turner D.C., Corlett P.R., Arana F.S., Morgan H.L., Absalom A.R., Adapa R., de Wit S., Everitt J.C., Gardner J.M., Pigott J.S., Haggard P., Fletcher P.C. Ketamine administration in healthy volunteers reproduces aberrant agency experiences associated with schizophrenia. Cognitive Neuropsychiatry 2011, 6:1-18.
37. Moore J.W., Fletcher P.C. Sense of agency in health and disease: a review of cue integration approaches. Consciousness and Cognition 2012, 21:59-68.
38. Moore J.W., Obhi S.S. Intentional binding and the sense of agency: a review. Consciousness and Cognition 2012, 21:546-561.
39. Morgan H.L., Turner D.C., Corlett P.R., Absalom A.R., Adapa R., Arana F.S., Pigott J.S., Gardner J.M., Everitt J.C., Haggard P., Fletcher P.C. Exploring the impact of ketamine on the experience of illusory body ownership. Biological Psychiatry 2011, 69:35-41.
40. Nelson B., Yung A.R., Bechdolf A., McGorry P.D. The phenomenological critique and self-disturbance: implications for ultra-high risk ("prodrome") research. Schizophrenia Bulletin 2008, 34:381-392.
41. Nelson B., Fornito A., Harrison B.J., Yücel M., Sass L.A., Yung A.R., Thompson A., Wood S.J., Pantelis C., McGorry P.D. A disturbed sense of self in the psychosis prodrome: linking phenomenology and neurobiology. Neuroscience and Biobehavioral Reviews 2009, 33:807-817.
42. Nelson B., Thompson A., Yung A.R. Basic self-disturbance predicts psychosis onset in the ultra high risk for psychosis "prodromal" population. Schizophrenia Bulletin 2012, 38:1277-1287.
43. Ortuño F., Guillén-Grima F., López-García P., Gómez J., Pla J. Functional neural networks of time perception: challenge and opportunity for schizophrenia research. Schizophrenia Research 2011, 125:129-135.
44. Parnas J., Handest P. Phenomenology of anomalous self experience in early schizophrenia. Comprehensive Psychiatry 2003, 44:121-134.
45. Schultze-Lutter Frauke Subjective symptoms of schizophrenia in research and the clinic: the basic symptom concept. Schizophrenia Bulletin 2009, 35:5-8.
46. Sass L.A., Parnas J. Schizophrenia, consciousness, and the self. Schizophrenia Bulletin 2003, 29:427-444.
47. Shergill S., Samson G., Bays P.M., Frith C.D., Wolpert D.M. Evidence for sensory prediction deficits in schizophrenia. American Journal of Psychiatry 2005, 162:2384-2386.
48. Stephens G.L., Graham G. When Self-consciousness Breaks 2000, MIT Press, Massachusetts.
49. Synofzik M., Vosgerau G., Newen A. Beyond the comparator model: a multifactorial two step account of agency. Consciousness and Cognition 2008, 17:219-239.
50. Synofzik M., Vosgerau G., Linder A. Me or not me- an optimal integration of agency cues?. Consciousness and Cognition 2009, 18:1065-1068.
51. Synofzik M., Their P., Leube D.T., Schlotterbeck P., Lindner A. Misattributions of agency in schizophrenia are based on imprecise predictions about the sensory consequences of one's actions. Brain 2010, 133(Pt. 1):262-271.
52. Synofzik M., Voss M. Disturbance of the sense of agency in schizophrenia. Neuropsychology of the Sense of Agency 2010, 145-155. Springer Verlag, Italia. M. Balconi (Ed.).
53. Takahata K., Takahashi H., Maeda T., Umeda S., Suhara T., Mimura M., Kato M. It's not my fault: postdictive modulation of intentional binding by monetary gains and losses. Plos One 2012, 7(12):e53421.
54. Tsakiris M., Schütz-Bosbach S., Gallagher S. On agency and body-ownership: phenomenological and neurocognitive reflections. Consciousness and Cognition 2007, 16:645-660.
55. Voss M., Moore J.W., Hauser M., Gallinat J., Heinz A., Haggard P. Altered awareness of action in schizophrenia: a specific deficit in predicting action consequences. Brain 2010, 133:3104-3112.
56. Wegner D.M., Sparrow B. Authorship processing. The Cognitive Neurosciences III 2004, 1201-1209. MIT Press, Cambrige, MA. M. Gazzaniga (Ed.).