RelB and the aryl hydrocarbon receptor: Dendritic cell tolerance at the epithelial interface

Immunology and Cell Biology

Volumn 91, Issue 9, 2013, Pages 543-544

  Thomas, Ranjeny ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 6 FORMYLINDOLO[3,2 B]CARBAZOLE; AROMATIC HYDROCARBON RECEPTOR; CARBAZOLE DERIVATIVE; CD103 ANTIGEN; CD11B ANTIGEN; CD1C ANTIGEN; CD8 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CCR6; CYTOKINE; ENDOTOXIN; INDIRUBIN; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 22; KYNURENINE; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR RELB; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANTIGEN PRESENTATION; CELL DIFFERENTIATION; CELL SURVIVAL; DENDRITIC CELL; EPITHELIUM; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; LANGERHANS CELL; LYMPHOCYTE PROLIFERATION; LYMPHOID ORGAN; MEMORY T LYMPHOCYTE; NONHUMAN; NOTE; ORGANOGENESIS; POLLUTANT; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; DENDRITIC CELLS; FEMALE; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; NF-KAPPA B; RECEPTORS, ARYL HYDROCARBON; TRANSCRIPTION FACTOR RELB;

EID: 84885445788     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2013.51     Document Type: Note

References (11)

1. Gerbal-Chaloin S, Iankova I, Maurel P, Daujat- Chavanieu M. Nuclear receptors in the cross-talk of drug metabolism and inflammation. Drug Metabol Rev 2013; 45: 122-144.
2. Millet P, McCall C, Yoza B. RelB: an outlier in leukocyte biology. J Leukocyte Biol (e-pub ahead of print 6 August 2013; doi:10.1189/jlb.0513305).
3. Shih VF, Davis-Turak J, Macal M, Huang JQ, Ponomarenko J, Kearns JD et al. Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-kappaB pathways. Nat Immunol 2012; 13: 1162-1170.
4. Martin E, O'Sullivan B, Low P, Thomas R. Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. Immunity 2003; 18: 155-167. (Pubitemid 36120696)
5. Vogel CFA, Wu D, Goth SR, Baek J, Lollies A, Domhardt R et al. Aryl hydrocarbon receptor signaling regulates NF-kB RelB activation during dendriticcell differentiation. Immunol Cell Biol 2013; 91: 568-575.
6. O'Sullivan BJ, Pai S, Street S, An X, MacDonald KP, Wong M et al. Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. J Immunol 2011; 187: 4018-4030.
7. Stefanova I, Dorfman JR, Germain RN. Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature 2002; 420: 429-434. (Pubitemid 35415655)
8. Cobbold SP, Adams E, Nolan KF, Regateiro FS, Waldmann H. Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link. Immunol Rev 2010; 236: 203-218.
9. Schlitzer A, McGovern N, Teo P, Zelante T, Atarashi K, Low D et al. IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity 2013; 38: 970-983.
10. Wu L, D'Amico A, Winkel KD, Suter M, Lo D, Shortman K. RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells. Immunity 1998; 9: 839-847. (Pubitemid 29024463)
11. Shklovskaya E, O'Sullivan BJ, Ng LG, Roediger B, Thomas R, Weninger W et al. Langerhans cells are precommitted to immune tolerance induction. Proc Natl Acad Sci USA 2011; 108: 18049-18054.