Hypoglycemic effect of polysaccharides with different molecular weight of Pseudostellaria heterophylla

BMC Complementary and Alternative Medicine

Volumn 13, Issue , 2013, Pages

  Hu, Juan ^a,b   Pang, Wensheng ^b,c   chen, Jinlong ^b   Bai, Shaowei ^b   Zheng, Zhenzhu ^a   Wu, Xiaohua ^d  

^a Fujian Academy of Traditional Chinese Medicine   (China)

^b FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c Internal Medicine of Second People's Hospital of Fujian Province   (China)

^d Fujian Lijiexun Pharmaceutical Co Ltd   (China)

Author keywords

Anti diabetes; Biomarkers; Molecular weight range; Polysaccharides; Pseudostellaria heterophylla

Indexed keywords

ADIPONECTIN; ALLOXAN; ARABINOSE; C REACTIVE PROTEIN; GALACTOSE; GALACTURONIC ACID; GLUCOSE; INSULIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; LEPTIN; MONOSACCHARIDE; ORAL ANTIDIABETIC AGENT; POLYSACCHARIDE; STREPTOZOCIN; TUMOR NECROSIS FACTOR ALPHA;

ALLOXAN DIABETES MELLITUS; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; CARBOHYDRATE ANALYSIS; CHINESE HERB; CHINESE MEDICINE; CONTROLLED STUDY; DOUBLE ANTIBODY SANDWICH ENZYME LINKED IMMUNOSORBENT ASSAY; DRUG MEGADOSE; GEL PERMEATION CHROMATOGRAPHY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TOLERANCE TEST; LOW DRUG DOSE; MALE; MOLECULAR WEIGHT; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PHENOL SULPHURIC ACID METHOD; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PSEUDOSTELLARIA HETEROPHYLLA; RAT; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; CARYOPHYLLACEAE; DIABETES MELLITUS, EXPERIMENTAL; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; GLUCOSE TOLERANCE TEST; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INTERLEUKIN-10; INTERLEUKIN-2; MALE; MICE; MOLECULAR WEIGHT; POLYSACCHARIDES; RATS; RATS, WISTAR; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885444877     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-13-267     Document Type: Article

References (26)

1. Holst JJ, Vilsb¢II T. Combining GLP-1 receptor agonists with insulin: therapeutic rationales and clinical findings. Diabetes Obes Metab 2013, 15(1):3-14.
2. Fang JG, Wei HK, Sun YY, Zhang XD, Liu WY, Chang QT, Wang RH, Gong YW. Regulation of podocalyxin expression in the kidney of streptozotocin-induced diabetic rats with Chinese herbs (Yishen capsule). BMC Complement Altern Med 2013, 76:1-6.
3. Li YJ, Xu HX. Research Progress on Anti · diabetic Chinese Medicines. Zhong Yao Cai 2006, 29(6):621-625.
4. Grant SJ, Chang DHT, Liu JX, Wong V, Kiat H, Bensoussan A. Chinese herbal medicine for impaired glucose tolerance: a randomized placebo controlled trial. BMC Complement Altern Med 2013, 104:1-8.
5. Teugwa CM, Boudjeko T, Tchinda BT, Mejiato PC, Zofou D. Anti-hyperglycaemic globulins from selected Cucurbitaceae seeds used as antidiabetic medicinal plants in Africa. BMC Complement Altern Med 2013, 63:1-7.
6. Guo XY, Yoshitomi H, Gao M, Qin LL, Duan Y, Sun W, Xu TH, Xie PF, Zhou JX, Huang LS, Liu TH. Guava leaf extracts promote glucose metabolism in SHRSP.Z-Leprfa/Izm rats by improving insulin resistance in skeletal muscle. BMC Complement Altern Med 2013, 52:1-8.
7. Pierre W, Gildas AJH, Ulrich MC, Modeste W-N, Benoît NT, Albert K. Hypoglycemic and hypolipidemic effects of Bersama engleriana leaves in nicotinamide/streptozotocin-induced type 2 diabetic rats. BMC Complement Altern Med 2012, 264:1-6.
8. Manya K, Champion B, Dunning T. The use of complementary and alternative medicine among people living with diabetes in Sydney. BMC Complement Altern Med 2012, 2:1-5.
9. Jiang ZS, Ni Q, Zhou XZ, Xing WJ, Ling L, Liu BY. Study on drug law of Type 2 diabetes based on structured clinical information acquisition system. J Shandong University of TCM 2007, 31(3):159-203.
10. Chen WN, Jiang M, Zheng G, Guo HT, Zhou Q, Lv AP. Exploring rules of Chinese patent medicines and Western medicines in treatment of type 2 diabetes with text mining. Chinese J Exp Tradit Med Formulae 2011, 17(21):299-302.
11. Ni Q, Chen SB, Zhou XZ, Wei ZX, Gao YB, Li Y, Wang XM, Li P, Lin L, Liu BY. Study of relationship between formula (herbs) and syndrome about Type 2 diabetes mellitus affiliated metabolic syndrome based on free-scale networks. Chinese Journal of Information on TCM 2006, 13(11):19-22.
12. Liu M, Wu K, Mao XQ, Wu Y, Ouyang JP. Astragalus polysaccharide improves insulin sensitivity in KKAy mice: Regulation of PKB/GLUT4 signaling in skeletal muscle. J Ethnopharmacol 2010, 127(1):32-37. 10.1016/j.jep.2009.09.055, 19800959.
13. Li WL, Zheng HC, Bukuru J, De-Kimpe N. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. J Ethnopharmacol 2004, 92(1):1-21. 10.1016/j.jep.2003.12.031, 15099842.
14. Chan CH, Ngoh GC, Yusoff R. Brief review on anti diabetic plants: Global distribution, active ingredients, extraction techniques and acting mechanisms. Pharmacogn Rev 2012, 6(11):22-28. 10.4103/0973-7847.95854, 3358964, 22654401.
15. Commission P. Pharmacopoeia of the People's Republic of China; Medical Science and Technology Press: Beijing. China 2010, 1:62-63.
16. Pang WS, Lin SD, Dai QW, Zhang HC, Hu J. Antitussive activity of pseudostellaria heterophylla (Miq.) pax extracts and improvement in lung function via adjustment of multi-cytokine levels. Molecules 2011, 16(4):3360-3370.
17. Xia LZ, Xu XX, Zhang R. Efects of Pseudostellaria Polysaccharides on Glucose and Lipid Metabolism in Diabetic Rats. China Pharmaceuticals 2009, l8:17-18.
18. Ni SD, Xia LZ, Xu XX, Zhang R. Efect of pseudostellaria polysaccharides in diabetic mice by alloxan. Anhui Medical and Pharmaceutical 2010, 14(5):521-522.
19. Xu JL, Xu AR, Ying JY, Ma WC, Chen YN. Effect of Pseudostellaria Polysaccharides on Glucose and Insulin Metabolism on Diabetic Rats. Chinese Arch Tradit Chinese Medicine 2012, 30(2):423-424.
20. Badawi A, Klip A, Haddad P, Cole DEC, Garcia BB, El-Sohemy A, Karmali M. Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention. Diabetes, Metab Syndr Obes 2010, 3:173-186. 3047967, 21437087.
21. Li YK, Jin RM, Wang QM. Experimental Methodology of TCM Pharmacology 2006, 603-607. Shanghai, China: Shanghai Science and Technology Press.
22. Ankur R, Shahjad A. Alloxan induced diabetes: mechanisms and effects. Int J Res Pharm Biomed Sci 2012, 3(2):819-823.
23. Duseja A, Thumburu KK, Das A, Dhiman RK, Chawla YK, Bhadada S, Bhansali A. Insulin tolerance test is comparable to homeostasis model assessment for insulin resistance in patients with nonalcoholic fatty liver disease. Indian J Gastroenterol 2007, 26(4):170-173.
24. Marianne BS, Jeffrey T, Géraldine P, Lorella M, Jan AE, Julie KC, Francois P, Philippe AH, Gordon CW, Marc YD. Increased Interleukin (IL)-1β Messenger Ribonucleic Acid Expression in β-Cells of Individuals with Type 2 Diabetes and Regulation of IL-1β in Human Islets by Glucose and Autostimulation. Clin Endocrinol Metab 2008, 93(10):4065-4074.
25. Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001, 7:941-946. 10.1038/90984, 11479627.
26. Ravipati S, Rajkuma B. Role of Leptin in Diabetes Mellitus. Indian J Fundam Appl Life Sci 2011, 1(2):209-214.