Effects of exercise with or without blueberries in the diet on cardio-metabolic risk factors: An exploratory pilot study in healthy subjects

Upsala Journal of Medical Sciences

Volumn 118, Issue 4, 2013, Pages 247-255

  Nyberg, Sofia ^a   Gerring, Edvard ^a   Gjellan, Solveig ^a   Vergara, Marta ^a   Lindström, Torbjörn ^a   Nystrom, Fredrik H ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Blueberries; Cholesterol; Exercise; Glucose; Running; Troponin

Indexed keywords

ANTIOXIDANT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; TROPONIN T;

ADULT; ARTICLE; BLOOD; BLUEBERRY; CARDIOVASCULAR DISEASE; CHEMISTRY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET; EXERCISE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; MALE; METABOLISM; MIDDLE AGED; NORMAL HUMAN; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; YOUNG ADULT;

ADULT; ANTIOXIDANTS; BLOOD GLUCOSE; BLUEBERRY PLANT; CARDIOVASCULAR DISEASES; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CROSS-OVER STUDIES; DIET; EXERCISE; FEMALE; HEALTHY VOLUNTEERS; HUMANS; INSULIN; MALE; MIDDLE AGED; PILOT PROJECTS; RISK FACTORS; TRIGLYCERIDES; TROPONIN T; YOUNG ADULT;

EID: 84885443990     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.3109/03009734.2013.825348     Document Type: Article

References (32)

1. Orchard TJ, Temprosa M, Goldberg R, Haffner S, Ratner R, Marcovina S, et al. The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann Intern Med. 2005; 142:611-19.
2. Saravia SG, Knebel F, Schroeckh S, Ziebig R, Lun A, Weimann A, et al. Cardiac troponin T release and inflammation demonstrated in marathon runners. Clin Lab. 2010; 56:51-8.
3. Goussetis E, Spiropoulos A, Tsironi M, Skenderi K, Margeli A, Graphakos S, et al. Spartathlon, a 246 kilometer foot race: effects of acute inflammation induced by prolonged exercise on circulating progenitor reparative cells. Blood Cells Mol Dis. 2009;42:294-9.
4. Neubauer O, Konig D, Wagner KH. Recovery after an Iron-man triathlon: sustained inflammatory responses and muscular stress. Eur J Appl Physiol. 2008;104:417-26.
5. Nakajima K, Kusuhara M, Yonemura A, Ayaori M, Saionji K, Tamai S, et al. Increasing physical fitness does not proportionally decrease circulating C-reactive protein level in men with varying fitness. Metabolism. 2008;57:650-7.
6. Margeli A, Skenderi K, Tsironi M, Hantzi E, Matalas AL, Vrettou C, et al. Dramatic elevations of interleukin-6-and acute-phase reactants in athletes participating in the ultradistance foot race spartathlon: severe systemic inflammation and lipid and lipoprotein changes in protracted exercise. J Clin Endocrinol Metab. 2005;90:3914-18.
7. Mattusch F, Dufaux B, Heine O, Mertens I, Rost R. Reduction of the plasma concentration of C-reactive protein following nine months of endurance training. Int J Sports Med. 2000;21:21-4.
8. Mingels AM, Jacobs LH, Kleijnen VW, Laufer EM, Winkens B, Hofstra L, et al. Cardiac troponin T elevations, using highly sensitive assay, in recreational running depend on running distance. Clin Res Cardiol. 2010;99:385-91.
9. Fu F, Nie J, Tong TK. Serum cardiac troponin T in adolescent runners: effects of exercise intensity and duration. Int J Sports Med. 2009;30:168-72.
10. de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA. 2010;304:2503-12.
11. Halliwell B. Antioxidants in human health and disease. Annu Rev Nutr. 1996;16:33-50.
12. Nichter M, Thompson JJ. For my wellness, not just my illness: North Americans' use of dietary supplements. Cult Med Psychiatry. 2006;30:175-222.
13. Velicer CM, Ulrich CM. Vitamin and mineral supplement use among US adults after cancer diagnosis: a systematic review. J Clin Oncol. 2008;26:665-73.
14. Spencer EH, Bendich A, Frank E. Vitamin and mineral supplement use among US medical students: a longitudinal study. J Am Diet Assoc. 2006;106:1975-83.
15. Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA. 2007;297:842-57.
16. Erlund I, Koli R, Alfthan G, Marniemi J, Puukka P, Mustonen P, et al. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr. 2008;87:323-31.
17. Ristow M, Zarse K, Oberbach A, Kloting N, Birringer M, Kiehntopf M, et al. Antioxidants prevent health-promoting effects of physical exercise in humans. Proc Natl Acad Sci U S A. 2009;106:8665-70.
18. Lyons MM, Yu C, Toma RB, Cho SY, Reiboldt W, Lee J, et al. Resveratrol in raw and baked blueberries and bilberries. J Agric Food Chem. 2003;51:5867-70.
19. Rodriguez-Mateos A, Cifuentes-Gomez T, Tabatabaee S, Lecras C, Spencer JP. Procyanidin, anthocyanin, and chloro-genic acid contents of highbush and lowbush blueberries. J Agric Food Chem. 2012; Epub ahead of print.
20. Wang SY, Chen CT, Sciarappa W, Wang CY, Camp MJ. Fruit quality, antioxidant capacity, and flavonoid content of organically and conventionally grown blueberries. J Agric Food Chem. 2008;56:5788-94.
21. Erlingsson S, Herard S, Dahlqvist Leinhard O, Lindstrom T, Lanne T, Borga M, et al. Men develop more intraabdominal obesity and signs of the metabolic syndrome after hyperali-mentation than women. Metabolism. 2009;58:995-1001.
22. Kechagias S, Ernersson A, Dahlqvist O, Lundberg P, Lindstrom T, Nystrom FH. Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects. Gut. 2008;57:649-54.
23. Duttaroy S, Thorell D, Karlsson L, Borjesson M. A singlebout of one-hour spinning exercise increases troponin T in healthy subjects. Scand Cardiovasc J. 2012;46:2-6.
24. Higashida K, Kim SH, Higuchi M, Holloszy JO, Han DH. Normal adaptations to exercise despite protection against oxida-tive stress. Am J Physiol Endocrinol Metab. 2011;301:E779-84.
25. Wallhuss A, Isik M, Nystrom FH. Comparison of the subjective sense of high or low metabolism and objectively measured resting metabolic rate. Scand J Clin Lab Invest. 2010; 70:334-7.
26. Lof M, Forsum E. Validation of energy intake by dietary recall against different methods to assess energy expenditure. J Hum Nutr Diet. 2004;17:471-80.
27. Kristal AR, Vizenor NC, Patterson RE, Neuhouser ML, Shattuck AL, McLerran D. Precision and bias of food frequency-based measures of fruit and vegetable intakes. Cancer Epidemiol Biomarkers Prev. 2000;9:939-44.
28. Yfanti C, Nielsen AR, Akerstrom T, Nielsen S, Rose AJ, Richter EA, et al. Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training. Am J Physiol Endocrinol Metab. 2011;300:E761-70.
29. Kurth-Kraczek EJ, Hirshman MF, Goodyear LJ, Winder WW. 5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle. Diabetes. 1999;48:1667-71.
30. Basu A, Rhone M, Lyons TJ. Berries: emerging impact on cardiovascular health. Nutr Rev. 2010;68:168-77.
31. Shukitt-Hale B. Blueberries and neuronal aging. Gerontology. 2012;58:518-23.
32. Kay CD, Holub BJ. The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxi-dant status in human subjects. Br J Nutr. 2002;88:389-98.