Arylthioamides as H2S donors: L-cysteine-activated releasing properties and vascular effects in vitro and in vivo

ACS Medicinal Chemistry Letters

Volumn 4, Issue 10, 2013, Pages 904-908

  Martelli, Alma ^a   Testai, Lara ^a   Citi, Valentina ^a   Marino, Alice ^a   Pugliesi, Isabella ^a   Barresi, Elisabetta ^a   Nesi, Giulia ^a   Rapposelli, Simona ^a   Taliani, Sabrina ^a   Da Settimo, Federico ^a   Breschi, Maria C ^a   Calderone, Vincenzo ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

cardiovascular system; hybrid drugs; Hydrogen sulphide; hypertension; potassium channels; thioamide; vascular smooth muscle

Indexed keywords

ARYLTHIOAMIDE DERIVATIVE; CYSTEINE; DIALLYL DISULFIDE; HYDROGEN SULFIDE; P HYDROXYBENZOTHIOAMIDE; THIOAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CARDIOVASCULAR DISEASE; CHROMATOGRAPHY; CONCENTRATION RESPONSE; CRYSTALLIZATION; DRUG EFFECT; DRUG HALF LIFE; DRUG RELEASE; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; SYSTOLIC BLOOD PRESSURE; VASCULAR RING; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

RATTUS;

EID: 84885443948     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml400239a     Document Type: Article

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