Effect of hydrogen sulphide-donating sildenafil (ACS6) on erectile function and oxidative stress in rabbit isolated corpus cavernosum and in hypertensive rats

BJU International

Volumn 103, Issue 11, 2009, Pages 1522-1529

  Shukla, Nilima ^a   Rossoni, Giuseppe ^b   Hotston, Matthew ^a   Sparatore, Anna ^c   Del Soldato, Piero ^d   Tazzari, Valerio ^d   Persad, Raj ^a   Angelini, Gianni D ^a   Jeremy, Jamie Y ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b University of Bristol ^*  (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d CTG Pharma SRL   (Italy)

Author keywords

Erectile dysfunction; Hydrogen sulphide; Sildenafil

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 8 ISOPROSTANE; BUTHIONINE SULFOXIMINE; CARBACHOL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; GLUTATHIONE; GLUTATHIONINE; HYDROGEN SULPHIDE DONATING SILDENAFIL; INTERLEUKIN 1BETA; PHOSPHODIESTERASE V; PHOSPHODIESTERASE V INHIBITOR; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SILDENAFIL; SODIUM HYDROSULFIDE; SULFIDE; SUPEROXIDE; THROMBOXANE A2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS CAVERNOSUM; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERTENSION; IN VIVO STUDY; MALE; NONHUMAN; OXIDATIVE STRESS; PENIS ERECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; RAT; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 5; DOWN-REGULATION; ERECTILE DYSFUNCTION; MALE; MUSCLE RELAXATION; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; PENILE ERECTION; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; PURINES; RABBITS; RATS; SULFONES;

EID: 65549108325     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2009.08415.x     Document Type: Article

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