Contributions of the Complementarity Determining Regions to the Thermal Stability of a Single-Domain Antibody

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Zabetakis, Dan ^a   Anderson, George P ^a   Bayya, Nikhil ^b   Goldman, Ellen R ^a  

^a NAVAL RESEARCH LABORATORY   (United States)

^b AMERICAN SOCIETY FOR ENGINEERING EDUCATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NANOBODY; SINGLE DOMAIN ANTIBODY A3; SINGLE DOMAIN ANTIBODY C8; SINGLE DOMAIN ANTIBODY D1; UNCLASSIFIED DRUG;

ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; MELTING POINT; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN MODIFICATION; PROTEIN STABILITY; THERMOSTABILITY;

AMINO ACID SEQUENCE; ANTIBODY AFFINITY; COMPLEMENTARITY DETERMINING REGIONS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN ENGINEERING; PROTEIN STABILITY; SINGLE-DOMAIN ANTIBODIES; TEMPERATURE; TRANSITION TEMPERATURE;

EID: 84885437046     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077678     Document Type: Article

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