-
1
-
-
0041631073
-
P21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD
-
12897128 10.1128/MCB.23.16.5526-5539.2003 1:CAS:528:DC%2BD3sXmt1Srtro%3D
-
Cotteret S, Jaffer ZM, Beeser A, Chernoff J (2003) p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD. Mol Cell Biol 23(16):5526-5539
-
(2003)
Mol Cell Biol
, vol.23
, Issue.16
, pp. 5526-5539
-
-
Cotteret, S.1
Jaffer, Z.M.2
Beeser, A.3
Chernoff, J.4
-
2
-
-
78449248030
-
P21-activated kinase 5 inhibits camptothecin-induced apoptosis in colorectal carcinoma cells
-
20567954 10.1007/s13277-010-0071-3 1:CAS:528:DC%2BC3cXht1OmtrvO
-
Wang X, Gong W, Qing H, Geng Y, Wang X, Zhang Y et al (2010) p21-activated kinase 5 inhibits camptothecin-induced apoptosis in colorectal carcinoma cells. Tumour Biol 31(6):575-582
-
(2010)
Tumour Biol
, vol.31
, Issue.6
, pp. 575-582
-
-
Wang, X.1
Gong, W.2
Qing, H.3
Geng, Y.4
Wang, X.5
Zhang, Y.6
-
3
-
-
0035842895
-
A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization
-
11733543 10.1083/jcb.200104123 1:CAS:528:DC%2BD3MXptVejsbk%3D
-
Cau J, Faure S, Comps M, Delsert C, Morin N (2001) A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization. J Cell Biol 155(6):1029-1042
-
(2001)
J Cell Biol
, vol.155
, Issue.6
, pp. 1029-1042
-
-
Cau, J.1
Faure, S.2
Comps, M.3
Delsert, C.4
Morin, N.5
-
4
-
-
38449120482
-
Signal transduction in Alzheimer disease: P21-activated kinase signaling requires C-terminal cleavage of APP at Asp664
-
17986220 10.1111/j.1471-4159.2007.05031.x 1:CAS:528:DC%2BD1cXivFaksLg%3D
-
Nguyen TV, Galvan V, Huang W, Banwait S, Tang H, Zhang J et al (2008) Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664. J Neurochem 104(4):1065-1080
-
(2008)
J Neurochem
, vol.104
, Issue.4
, pp. 1065-1080
-
-
Nguyen, T.V.1
Galvan, V.2
Huang, W.3
Banwait, S.4
Tang, H.5
Zhang, J.6
-
5
-
-
33846818859
-
Crystal structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs
-
17292838 10.1016/j.str.2007.01.001 1:CAS:528:DC%2BD2sXhs1Smsro%3D
-
Eswaran J, Lee WH, Debreczeni JE, Filippakopoulos P, Turnbull A, Fedorov O et al (2007) Crystal structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs. Structure 15(2):201-213
-
(2007)
Structure
, vol.15
, Issue.2
, pp. 201-213
-
-
Eswaran, J.1
Lee, W.H.2
Debreczeni, J.E.3
Filippakopoulos, P.4
Turnbull, A.5
Fedorov, O.6
-
6
-
-
0035341895
-
The Ste20 group kinases as regulators of MAP kinase cascades
-
11316611 10.1016/S0962-8924(01)01980-8 1:CAS:528:DC%2BD3MXislGntrk%3D
-
Dan I, Watanabe NM, Kusumi A (2001) The Ste20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol 11(5):220-230
-
(2001)
Trends Cell Biol
, vol.11
, Issue.5
, pp. 220-230
-
-
Dan, I.1
Watanabe, N.M.2
Kusumi, A.3
-
7
-
-
33645815687
-
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
-
16581795 10.1128/MCB.26.8.3215-3230.2006 1:CAS:528:DC%2BD28Xjs1SltLo%3D
-
Cotteret S, Chernoff J (2006) Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties. Mol Cell Biol 26(8):3215-3230
-
(2006)
Mol Cell Biol
, vol.26
, Issue.8
, pp. 3215-3230
-
-
Cotteret, S.1
Chernoff, J.2
-
8
-
-
0036135015
-
PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells
-
11756552 10.1128/MCB.22.2.567-577.2002 1:CAS:528:DC%2BD38XhvVeqsw%3D%3D
-
Dan C, Nath N, Liberto M, Minden A (2002) PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells. Mol Cell Biol 22(2):567-577
-
(2002)
Mol Cell Biol
, vol.22
, Issue.2
, pp. 567-577
-
-
Dan, C.1
Nath, N.2
Liberto, M.3
Minden, A.4
-
9
-
-
44149122564
-
ROCK, PAK, and Toll of synapses in Alzheimer's disease
-
18466762 10.1016/j.bbrc.2008.04.148 1:CAS:528:DC%2BD1cXmsFyrsL4%3D
-
Salminen A, Suuronen T, Kaarniranta K (2008) ROCK, PAK, and Toll of synapses in Alzheimer's disease. Biochem Biophys Res Commun 371(4):587-590
-
(2008)
Biochem Biophys Res Commun
, vol.371
, Issue.4
, pp. 587-590
-
-
Salminen, A.1
Suuronen, T.2
Kaarniranta, K.3
-
10
-
-
33750146478
-
Signaling from MARK to tau: Regulation, cytoskeletal crosstalk, and pathological phosphorylation
-
17047359 10.1159/000095258 1:CAS:528:DC%2BD28XhtV2hu7jI
-
Timm T, Matenia D, Li XY, Griesshaber B, Mandelkow EM (2006) Signaling from MARK to tau: regulation, cytoskeletal crosstalk, and pathological phosphorylation. Neurodegener Dis 3(4-5):207-217
-
(2006)
Neurodegener Dis
, vol.3
, Issue.4-5
, pp. 207-217
-
-
Timm, T.1
Matenia, D.2
Li, X.Y.3
Griesshaber, B.4
Mandelkow, E.M.5
-
11
-
-
58149465743
-
Epidemiology of ovarian cancer
-
19107446 10.1007/978-1-60327-492-0-20
-
Permuth-Wey J, Sellers TA (2009) Epidemiology of ovarian cancer. Methods Mol Biol 472:413-437
-
(2009)
Methods Mol Biol
, vol.472
, pp. 413-437
-
-
Permuth-Wey, J.1
Sellers, T.A.2
-
12
-
-
0346057794
-
Resistance to chemotherapy in advanced ovarian cancer: Mechanisms and current strategies
-
14661043 10.1038/sj.bjc.6601497 1:CAS:528:DC%2BD3sXpsFOns7c%3D
-
Vasey PA (2003) Resistance to chemotherapy in advanced ovarian cancer: mechanisms and current strategies. Br J Cancer 89(Suppl 3):S23-S28
-
(2003)
Br J Cancer
, vol.89
, Issue.SUPPL. 3
-
-
Vasey, P.A.1
-
13
-
-
0015211527
-
Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
-
5553076 10.1021/ja00738a045 1:CAS:528:DyaE3MXktVKisLc%3D
-
Wani MC, Taylor HL, Wall ME, Coggon P, McPhail AT (1971) Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J Am Chem Soc 93(9):2325-2327
-
(1971)
J Am Chem Soc
, vol.93
, Issue.9
, pp. 2325-2327
-
-
Wani, M.C.1
Taylor, H.L.2
Wall, M.E.3
Coggon, P.4
McPhail, A.T.5
-
14
-
-
0028857271
-
A "quickscore" method for immunohistochemical semiquantitation: Validation for oestrogen receptor in breast carcinomas
-
7490328 10.1136/jcp.48.9.876 1:STN:280:DyaK28%2Fps1arsQ%3D%3D
-
Detre S, Saclani Jotti G, Dowsett M (1995) A "quickscore" method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas. J Clin Pathol 48(9):876-878
-
(1995)
J Clin Pathol
, vol.48
, Issue.9
, pp. 876-878
-
-
Detre, S.1
Saclani Jotti, G.2
Dowsett, M.3
-
15
-
-
84865983430
-
Characterization and in vitro bioactivity evaluation of paclitaxel-loaded polyester nanoparticles
-
22713593 1:CAS:528:DC%2BC38Xht1GiurbM
-
Lopez-Gasco P, Iglesias I, Benedi J, Lozano R, Blanco MD (2012) Characterization and in vitro bioactivity evaluation of paclitaxel-loaded polyester nanoparticles. Anticancer Drugs 23(9):947-958
-
(2012)
Anticancer Drugs
, vol.23
, Issue.9
, pp. 947-958
-
-
Lopez-Gasco, P.1
Iglesias, I.2
Benedi, J.3
Lozano, R.4
Blanco, M.D.5
-
16
-
-
0346462998
-
P21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells
-
14530270 10.1074/jbc.M309937200 1:CAS:528:DC%2BD2cXhtV2jtA%3D%3D
-
Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK et al (2004) p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. J Biol Chem 279(2):1422-1428
-
(2004)
J Biol Chem
, vol.279
, Issue.2
, pp. 1422-1428
-
-
Balasenthil, S.1
Sahin, A.A.2
Barnes, C.J.3
Wang, R.A.4
Pestell, R.G.5
Vadlamudi, R.K.6
-
17
-
-
33646940460
-
Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients
-
16705121 10.1093/jnci/djj185 1:CAS:528:DC%2BD28XkvVSrs78%3D
-
Holm C, Rayala S, Jirstrom K, Stal O, Kumar R, Landberg G (2006) Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients. J Natl Cancer Inst 98(10):671-680
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.10
, pp. 671-680
-
-
Holm, C.1
Rayala, S.2
Jirstrom, K.3
Stal, O.4
Kumar, R.5
Landberg, G.6
-
18
-
-
2542452838
-
Pak-1 expression increases with progression of colorectal carcinomas to metastasis
-
15161701 10.1158/1078-0432.CCR-03-0210 1:CAS:528:DC%2BD2cXkt1Ghsb0%3D
-
Carter JH, Douglass LE, Deddens JA, Colligan BM, Bhatt TR, Pemberton JO et al (2004) Pak-1 expression increases with progression of colorectal carcinomas to metastasis. Clin Cancer Res 10(10):3448-3456
-
(2004)
Clin Cancer Res
, vol.10
, Issue.10
, pp. 3448-3456
-
-
Carter, J.H.1
Douglass, L.E.2
Deddens, J.A.3
Colligan, B.M.4
Bhatt, T.R.5
Pemberton, J.O.6
-
19
-
-
0037107548
-
PAK4 is activated via PI3K in HGF-stimulated epithelial cells
-
12244132 10.1242/jcs.00080 1:CAS:528:DC%2BD38Xos12ktb4%3D
-
Wells CM, Abo A, Ridley AJ (2002) PAK4 is activated via PI3K in HGF-stimulated epithelial cells. J Cell Sci 115(Pt 20):3947-3956
-
(2002)
J Cell Sci
, vol.115
, Issue.PART 20
, pp. 3947-3956
-
-
Wells, C.M.1
Abo, A.2
Ridley, A.J.3
-
20
-
-
24344494856
-
PAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin
-
16014608 10.1091/mbc.E05-01-0081 1:CAS:528:DC%2BD2MXpvFKltrc%3D
-
Matenia D, Griesshaber B, Li XY, Thiessen A, Johne C, Jiao J et al (2005) PAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin. Mol Biol Cell 16(9):4410-4422
-
(2005)
Mol Biol Cell
, vol.16
, Issue.9
, pp. 4410-4422
-
-
Matenia, D.1
Griesshaber, B.2
Li, X.Y.3
Thiessen, A.4
Johne, C.5
Jiao, J.6
-
21
-
-
85047695282
-
Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain
-
12032833 10.1038/sj.onc.1205478 1:CAS:528:DC%2BD38Xks12nsrY%3D
-
Pandey A, Dan I, Kristiansen TZ, Watanabe NM, Voldby J, Kajikawa E et al (2002) Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain. Oncogene 21(24):3939-3948
-
(2002)
Oncogene
, vol.21
, Issue.24
, pp. 3939-3948
-
-
Pandey, A.1
Dan, I.2
Kristiansen, T.Z.3
Watanabe, N.M.4
Voldby, J.5
Kajikawa, E.6
-
22
-
-
68949207907
-
Combined inhibition of PAK7, MAP3K7 and CK2alpha kinases inhibits the growth of MiaPaCa2 pancreatic cancer cell xenografts
-
19363471 10.1038/cgt.2009.22 1:CAS:528:DC%2BD1MXksVentb0%3D
-
Giroux V, Iovanna JL, Garcia S, Dagorn JC (2009) Combined inhibition of PAK7, MAP3K7 and CK2alpha kinases inhibits the growth of MiaPaCa2 pancreatic cancer cell xenografts. Cancer Gene Ther 16(9):731-740
-
(2009)
Cancer Gene Ther
, vol.16
, Issue.9
, pp. 731-740
-
-
Giroux, V.1
Iovanna, J.L.2
Garcia, S.3
Dagorn, J.C.4
-
23
-
-
78449309713
-
Chemoresistance testing of human ovarian cancer cells and its in vitro model
-
20736059 10.1016/j.tiv.2010.08.010 1:CAS:528:DC%2BC3cXhsVGntrjK
-
Brigulova K, Cervinka M, Tosner J, Sedlakova I (2010) Chemoresistance testing of human ovarian cancer cells and its in vitro model. Toxicol In Vitro 24(8):2108-2115
-
(2010)
Toxicol in Vitro
, vol.24
, Issue.8
, pp. 2108-2115
-
-
Brigulova, K.1
Cervinka, M.2
Tosner, J.3
Sedlakova, I.4
-
24
-
-
84864553897
-
Correlation of pretreatment drug induced apoptosis in ovarian cancer cells with patient survival and clinical response
-
22873358 10.1186/1479-5876-10-162 1:CAS:528:DC%2BC38XhvVShsr%2FM
-
Salom E, Penalver M, Homesley H, Burrell M, Garrett A, Presant CA et al (2012) Correlation of pretreatment drug induced apoptosis in ovarian cancer cells with patient survival and clinical response. J Transl Med 10(1):162
-
(2012)
J Transl Med
, vol.10
, Issue.1
, pp. 162
-
-
Salom, E.1
Penalver, M.2
Homesley, H.3
Burrell, M.4
Garrett, A.5
Presant, C.A.6
-
25
-
-
51849136395
-
P21 activated kinase 5 activates Raf-1 and targets it to mitochondria
-
18465753 10.1002/jcb.21809 1:CAS:528:DC%2BD1cXhtFGns7%2FE
-
Wu X, Carr HS, Dan I, Ruvolo PP, Frost JA (2008) p21 activated kinase 5 activates Raf-1 and targets it to mitochondria. J Cell Biochem 105(1):167-175
-
(2008)
J Cell Biochem
, vol.105
, Issue.1
, pp. 167-175
-
-
Wu, X.1
Carr, H.S.2
Dan, I.3
Ruvolo, P.P.4
Frost, J.A.5
|