CCR2 Regulates the Uptake of Bone Marrow-Derived Fibroblasts in Renal Fibrosis

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Xia, Yunfeng ^a,b   Entman, Mark L ^a   Wang, Yanlin ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CALVASCULIN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR2; COLLAGEN; COLLAGEN TYPE 1; CXCL16 CHEMOKINE; FIBRONECTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROCOLLAGEN; PROCOLLAGEN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL INFILTRATION; CHIMERA; CONTROLLED STUDY; CXCL16 GENE; EPITHELIUM CELL; FIBROBLAST; GENE DELETION; HEMATOPOIETIC STEM CELL; INFLAMMATION; KIDNEY FIBROSIS; KIDNEY TUBULE EPITHELIUM; KNOCKOUT MOUSE; LIGAND BINDING; MACROPHAGE; MALE; MCP 1 GENE; MESENCHYME CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BONE MARROW; CELL LINE; CHEMOKINE CCL2; CHEMOKINE CXCL6; COLLAGEN TYPE I; FIBROBLASTS; GENE DELETION; GENE EXPRESSION REGULATION; KIDNEY; KIDNEY DISEASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOFIBROBLASTS; RECEPTORS, CCR2;

EID: 84885397149     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077493     Document Type: Article

References (39)

1. Schainuck LI, Striker GE, Cutler RE, Benditt EP, (1970) Structural-functional correlations in renal disease. II. The correlations. Hum Pathol 1: 631-641. PubMed: 5521736.
2. Nath KA, (1998) The tubulointerstitium in progressive renal disease. Kidney Int 54: 992-994. PubMed: 9734628.
3. Eddy AA, (2000) Molecular basis of renal fibrosis. Pediatr Nephrol 15: 290-301. PubMed: 11149129.
4. Neilson EG, (2006) Mechanisms of disease: Fibroblasts--a new look at an old problem. Nat Clin Pract Nephrol 2: 101-108. PubMed: 16932401.
5. Strutz F, Müller GA, (2006) Renal fibrosis and the origin of the renal fibroblast. Nephrol Dial Transplant 21: 3368-3370. PubMed: 16887850.
6. Liu Y, (2006) Renal fibrosis: new insights into the pathogenesis and therapeutics. Kidney Int 69: 213-217. PubMed: 16408108.
7. Sakai N, Wada T, Yokoyama H, Lipp M, Ueha S, et al. (2006) Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis. Proc Natl Acad Sci U S A 103: 14098-14103. PubMed: 16966615.
8. Grimm PC, Nickerson P, Jeffery J, Savani RC, Gough J, et al. (2001) Neointimal and tubulointerstitial infiltration by recipient mesenchymal cells in chronic renal-allograft rejection. N Engl J Med 345: 93-97. PubMed: 11450677.
9. Broekema M, Harmsen MC, van Luyn MJ, Koerts JA, Petersen AH, et al. (2007) Bone marrow-derived myofibroblasts contribute to the renal interstitial myofibroblast population and produce procollagen I after ischemia/reperfusion in rats. J Am Soc Nephrol 18: 165-175. PubMed: 17135399.
10. Chen G, Lin SC, Chen J, He L, Dong F, et al. (2011) CXCL16 recruits bone marrow-derived fibroblast precursors in renal fibrosis. J Am Soc Nephrol 22: 1876-1886. PubMed: 21816936.
11. Li J, Deane JA, Campanale NV, Bertram JF, Ricardo SD, (2007) The contribution of bone marrow-derived cells to the development of renal interstitial fibrosis. Stem Cells 25: 697-706. PubMed: 17170067.
12. Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A, (1994) Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med 1: 71-81. PubMed: 8790603.
13. Niedermeier M, Reich B, Rodriguez Gomez M, Denzel A, Schmidbauer K, et al. (2009) CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes. Proc Natl Acad Sci U S A 106: 17892-17897. PubMed: 19815530.
14. Shao DD, Suresh R, Vakil V, Gomer RH, Pilling D, (2008) Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation. J Leukoc Biol 83: 1323-1333. PubMed: 18332234.
15. Haudek SB, Trial J, Xia Y, Gupta D, Pilling D, et al. (2008) Fc receptor engagement mediates differentiation of cardiac fibroblast precursor cells. Proc Natl Acad Sci U S A 105: 10179-10184. PubMed: 18632582.
16. Yang J, Lin SC, Chen G, He L, Hu Z, et al. (2013) Adiponectin Promotes Monocyte-to-Fibroblast Transition in Renal Fibrosis. J Am Soc Nephrol (. (2013)) PubMed: 23833260.
17. Metz CN, (2003) Fibrocytes: a unique cell population implicated in wound healing. Cell Mol Life Sci 60: 1342-1350. PubMed: 12943223.
18. Quan TE, Cowper S, Wu SP, Bockenstedt LK, Bucala R, (2004) Circulating fibrocytes: collagen-secreting cells of the peripheral blood. Int J Biochem Cell Biol 36: 598-606. PubMed: 15010326.
19. Abe R, Donnelly SC, Peng T, Bucala R, Metz CN, (2001) Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J Immunol 166: 7556-7562. PubMed: 11390511.
20. Lebleu VS, Taduri G, O'Connell J, Teng Y, Cooke VG, et al. (2013) Origin and function of myofibroblasts in kidney fibrosis. Nat Med 19: 1047-1053. PubMed: 23817022.
21. Murphy PM, (1994) The molecular biology of leukocyte chemoattractant receptors. Annu Rev Immunol 12: 593-633. PubMed: 8011292.
22. Xu J, Lin SC, Chen J, Miao Y, Taffet GE, et al. (2011) CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis. Am J Physiol Heart Circ Physiol 301: H538-H547. PubMed: 21572015.
23. Kisseleva T, Uchinami H, Feirt N, Quintana-Bustamante O, Segovia JC, et al. (2006) Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J Hepatol 45: 429-438. PubMed: 16846660.
24. Yang J, Chen J, Yan J, Zhang L, Chen G, et al. (2012) Effect of interleukin 6 deficiency on renal interstitial fibrosis. PLOS ONE 7: e52415. PubMed: 23272241.
25. Haudek SB, Cheng J, Du J, Wang Y, Hermosillo-Rodriguez J, et al. (2010) Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy. J Mol Cell Cardiol 49: 499-507. PubMed: 20488188.
26. Abel S, Hundhausen C, Mentlein R, Schulte A, Berkhout TA, et al. (2004) The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10. J Immunol 172: 6362-6372. PubMed: 15128827.
27. Picard N, Baum O, Vogetseder A, Kaissling B, Le Hir M, (2008) Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat. Histochem Cell Biol 130: 141-155. PubMed: 18449560.
28. Qi W, Chen X, Poronnik P, Pollock CA, (2006) The renal cortical fibroblast in renal tubulointerstitial fibrosis. Int J Biochem Cell Biol 38: 1-5. PubMed: 16230044.
29. Powell DW, Mifflin RC, Valentich JD, Crowe SE, Saada JI, et al. (1999) Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol 277: C1-C9. PubMed: 10409103.
30. Iwano M, Plieth D, Danoff TM, Xue C, Okada H, et al. (2002) Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 110: 341-350. PubMed: 12163453.
31. Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A, (2003) Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494. PubMed: 14617750.
32. Zeisberg M, Kalluri R, (2004) The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med 82: 175-181. PubMed: 14752606.
33. Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R, (2008) Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. J Am Soc Nephrol 19: 2282-2287. PubMed: 18987304.
34. Chesney J, Bacher M, Bender A, Bucala R, (1997) The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ. Proc Natl Acad Sci U S A 94: 6307-6312. PubMed: 9177213.
35. Chesney J, Bucala R, (1997) Peripheral blood fibrocytes: novel fibroblast-like cells that present antigen and mediate tissue repair. Biochem Soc Trans 25: 520-524. PubMed: 9191147.
36. Phillips RJ, Burdick MD, Hong K, Lutz MA, Murray LA, et al. (2004) Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. J Clin Invest 114: 438-446. PubMed: 15286810.
37. Moore BB, Kolodsick JE, Thannickal VJ, Cooke K, Moore TA, et al. (2005) CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury. Am J Pathol 166: 675-684. PubMed: 15743780.
38. Haudek SB, Xia Y, Huebener P, Lee JM, Carlson S, et al. (2006) Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice. Proc Natl Acad Sci U S A 103: 18284-18289. PubMed: 17114286.
39. Eddy AA, (2005) Progression in chronic kidney disease. Adv Chronic Kidney Dis 12: 353-365. PubMed: 16198274.