Proton pump inhibitors are not the key for therapying non-steroidal anti-inflammatory drugs-induced small intestinal injury

Rheumatology International

Volumn 33, Issue 10, 2013, Pages 2513-2521

  Zhang, Shuo ^a   Chao, Guan Qun ^a   Lu, Bin ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Enteropathy; Mechanical barrier; Non steroidal anti inflammatory drugs; Proton pump inhibitors

Indexed keywords

DICLOFENAC; EPIDERMAL GROWTH FACTOR; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PANTOPRAZOLE; PROTON PUMP INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; CLINICAL PRACTICE; CONTROLLED STUDY; DRUG EFFECT; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE INJURY; INTESTINE ULCER; JEJUNUM; MALE; NONHUMAN; PHOTOMETRY; PORTAL VEIN BLOOD; PRIORITY JOURNAL; RAT; SMALL INTESTINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DICLOFENAC; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; OMEPRAZOLE; PROTON PUMP INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84885389586     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-013-2756-6     Document Type: Article

References (34)

1. Baum C, Kennedy DL, Forbes MB (1985) Utilization of non-steroidal anti-inflammatory drugs. Arthr Rheum 28:686-692
2. O'Brien VM, Bagdy GF (1985) Rare adverse reactions to non-steroidal anti-inflammatory drugs. J Rheumatol 12:13-20
3. Baltoyiannis G, Christodoulos N, Mitsis M, Stephanou D, Ioannou H, Nousias V, Kappas AM (2001) A comparative experimental study of the effects of diclofenac and ketoprofen on the small-bowel mucosa of canines. Res Exp Med (Berl) 200(2):125-135
4. Allison MC, Howatson AG, Torrance CJ, Lee FD, Russell RI (1992) Gastrointestinal damage associated with the use of non-steroidal anti-inflammatory drugs. N Engl J Med 327:749-754
5. Bjarnason I, Zanelli G, Smith T, Prouse P, Williams P, Smethurst P, Delacey G, Gumpel MJ, Levi AJ (1987) Nonsteroidal anti-inflammatory drug-induced intestinal inflammation in humans. Gastroenterology 93:480-489
6. Sidhu R, Sanders DS, McAlindon ME, Kapur K (2006) Capsule endoscopy for the evaluation of nonsteroidal anti-inflammatory drug induced enteropathy: United Kingdom pilot data. Gastrointest Endosc 64:1035
7. Maiden L, Thjodleifsson B, Seigal A, Bjarnason II, Scott D, Birgisson S et al (2007) Long-term effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective agents on the small bowel: a cross-sectional capsule enteroscopy study. Clin Gastroenterol Hepatol 5:1040-1045
8. Lai KC, Lam SK, Chu KM, Hui WM, Kwok KF, Wong BC, Hu HC, Wong WM, Chan OO, Chan CK (2003) Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in nonsteroidal anti-inflammatory drug users: a randomized trial. Aliment Pharmacol Ther 18:829-836
9. Simon WA, Sturm E, Hartmann HJ, Weser U (2006) Hydroxyl radical scavenging reactivity of proton pump inhibitors. Biochem Pharmacol 71:1337-1341
10. Kuroda M, Yoshida N, Ichikawa H, Takagi T, Okuda T, Naito Y, Okanoue T, Yoshikawa T (2006) Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis. Int J Mol Med 17:89-93
11. Thomson RD, Lestina LS, Bensen SP, Toor A, Maheshwari Y, Ratcliffe NR (2002) Lansoprazole associated microscopic colitis: a case series. Am J Gastroenterol 97:2908-2913
12. Goldstein JL, Eisen GM, Lewis B, Gralnek IM, Zlotnick S, Fort JG (2005) Investigators. Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole and placebo. Clin Gastroenterol Hepatol 3:133-141
13. Graham DY, Opekun AR, Willingham FF et al (2005) Visible small-intestinal mucosal injury in chronic NSAID users. Clin Gastroenterol Hepatol 3:55-59
14. Maiden L, Thjodleifsson B, Theodors A et al (2005) A quantitative analysis of NSAID-induced small bowel pathology by capsule endoscopy. Gastroenterology 128:1172-1178
15. Fujimora S, Gudis K, Takahashi Y et al (2010) Distribution of small intestinal mucosal injuries as a result of NSAID administration. Eur J Clin Invest 40:504-510
16. Chan FK, Lanas A, Scheiman J, Berger MF, Nguyen H, Goldstein JL (2010) Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial. Lancet 376(9736):173-179
17. McCarthy DM (2009) GI bleeding: problems that persist. Gastrointest Endosc 70:225-228
18. Wallace JL, Keenan CM, Gale D, Shoupe TS (1992) Exacerbation of experimental colitis by nonsteroidal antiinflammatory drugs is not related to elevated leukotriene B4 synthesis. Gastroenterology 102:18-27
19. Chin CJ, Mcardle AH, Brown R et al (1970) Intestinal mucosal lesions in low flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg 101:478-483
20. Whiteland JL, Shimeld C, Nicholls SM, Easty DL, Williams NA, Hill TJ (1997) Immunohistochemical detection of cytokines in paraffin-embedded mouse tissues. J Immunol Methods 210:103-108
21. Wolfe MM, Lichtenstein DR, Singh G (1999) Gastrointestinal toxicity of nonsteroidal anti-inflammatory drugs. N Engl J Med 340:1888-1899
22. Bjarnason I, Hayllar J, MacPherson AJ et al (1993) Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology 104:1832-1847
23. Wallace JL (2008) Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn't the stomach digest itself? Physiol Rev 88:1547-1565
24. Sigthorsson G, Crane R, Simon T, Hoover M, Quan H, Bolognese J, Bjarnason I (2000) COX-2 inhibition with rofecoxib does not increase intestinal permeability in healthy subjects: a double blind crossover study comparing rofecoxib with placebo and indomethacin. Gut 47:527-532
25. Lanas A, Scarpignato C (2006) Microbial flora in NSAID-induced intestinal damage: a role for antibiotics? Digestion 73(S):136-150
26. Reuter BK, Davies NM, Wallace JL (1997) Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria and enterohepatic circulation. Gastroenterology 112:109-117
27. Thiefin G, Beaugerie L (2005) Toxic effects of nonsteroidal antiinflammatory drugs on the small bowel, colon, and rectum. Joint Bone Spine 72:286-294
28. Langtry HD, Wilde MI (1998) Omeprazole. A review of its use in Helicobacter pylori infection, gastro-esophageal reflux disease and peptic ulcers impaired by non-steroidal anti-inflammatory drugs. Drugs 56:447-486
29. Hawkey CJ, Karrasch JA, Szczepañski L, Walker DG, Barkun A, Swannell AJ, Yeomans ND (1998) Omeprazole compared with misoprostol for ulcers associated with nonsteroidal anti-inflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) study Group. N Engl J Med 338:727-734
30. Wallace JL, Syer S, Denou E, de Palma G, Vong L, McKnight W, Jury J, Bolla M, Bercik P, Collins SM, Verdu E, Ongini E (2011) Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis. Gastroenterology 141(4):1314-1322
31. Playford RJ, Wright NA (1996) Why is epidermal growth factor present in the gut lumen? Gut 38:303-305
32. Buret A, Olson ME, Gall DG, Hardin JA (1998) Effects of orally administered epidermal growth factor on enteropathogenic Escherichia coli infection in rabbits. Infect Immun 66:4917-4923
33. Hardin JA, Chung B, O'Loughlin EV, Gall DG (1999) The effect of epidermal growth factor on brush border surface area and function in the distal remnant following resection in the rabbit. Gut 44:26-32
34. Riegler M, Sedivy R, Sogukoglu T, Cosentini E, Bischof G, Teleky B, Feil W, Schiessel R, Hamilton G, Wenzl E (1996) Epidermal growth factor promotes rapid response to epithelial injury in rabbit duodenum in vitro. Gastroenterology 111:28-36