Mutant MCP-1 protein delivery from layer-by-layer coatings onorthopedic implants to modulate inflammatory response

Biomaterials

Volumn 34, Issue 38, 2013, Pages 10287-10295

  Keeney, Michael ^a   Waters, Heather ^a   Barcay, Katherine ^a   Jiang, Xinyi ^a   Yao, Zhenyu ^a   Pajarinen, Jukka ^a   Egashira, Kensuke ^c   Goodman, Stuart B ^a,b   Yang, Fan ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Controlled drug release; Inflammation; Macrophage; Titanium; Wear debris

Indexed keywords

CONTROLLED DRUG RELEASE; FLUORESCENCE IMAGING; INFLAMMATION; INFLAMMATORY RESPONSE; POLYELECTROLYTE SOLUTIONS; PROSTHETIC LOOSENING; TOTAL JOINT REPLACEMENT; WEAR DEBRIS;

ARTHROPLASTY; DEGRADATION; JOINTS (ANATOMY); MACROPHAGES; POLYELECTROLYTES; PROTEINS; SCANNING ELECTRON MICROSCOPY; TITANIUM;

COATINGS;

7ND PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MUTANT PROTEIN; POLYELECTROLYTE; POLYMER; TITANIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHROPLASTY; ARTICLE; AUTOFLUORESCENCE IMAGING; BIOLOGICAL ACTIVITY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DEGRADATION; FEMALE; FEMUR; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; INFLAMMATION; JOINT PROSTHESIS; MACROPHAGE; MACROPHAGE MIGRATION; MALE; MOUSE; NONHUMAN; ORTHOPEDIC IMPLANT; PH; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURGICAL TECHNIQUE; TOTAL KNEE REPLACEMENT;

CONTROLLED DRUG RELEASE; INFLAMMATION; MACROPHAGE; TITANIUM; WEAR DEBRIS;

ANIMALS; CELL LINE; CHEMOKINE CCL2; FEMALE; HUMANS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; ORTHOPEDICS; PROSTHESES AND IMPLANTS;

EID: 84885388708     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.09.028     Document Type: Article

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